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The map label for this gene is cssR [H]

Identifier: 226947519

GI number: 226947519

Start: 341182

End: 341856

Strand: Direct

Name: cssR [H]

Synonym: CLM_0353

Alternate gene names: 226947519

Gene position: 341182-341856 (Clockwise)

Preceding gene: 226947518

Following gene: 226947520

Centisome position: 8.21

GC content: 28.74

Gene sequence:

>675_bases
ATGGGAAGAAAAGTCTATCTTGTTGAAGATGAAAAAAGTCTGAATATATTATTAGAAAAGTATCTACAACGTGAAGGGTA
TGAAGTAACTACTTTTTTTAATGGAAGCTCTGCAATAGAGAGAATAAAAGATGTCCCAGATCTTTGGATATTAGATATAA
TGTTACCTGATATAGATGGATATCAAATAATTAAAGCTGTAAAAGAAAACAATAAAAATACTCCAGTTATTTTTATGTCT
GCGAGGAATGAGGAACTGGATAGAGTGGTGGGATTAGAATTAGGAAGTGATGATTATTTATCAAAGCCATTTTTACCTAG
AGAGCTTATAATAAGAACTAATAAACTTATGGAAAGAATTTATGGGAAAAGTAATAATTCTATGGACATAATTACAAATA
TTGGAGAGTACAAAATAAGTAAAAGACAAAGAGCTGTTTTTTTCGGAGAAAAAGAAATTCAACTAACAAACAAAGAGTTT
GAACTATTAAATTTTTTTGTAGAGAATAGAAACAATGTTATATCTAGAGAACAAATTTTAATTAGTATTTGGGGAGATGA
TTATTTCGGATCCGATAGAGTTATTGATGATACAATTAGGAGATTGCGCAAAAAGATGGATAAGTTAGATCTTGAAACTG
TATATGGATATGGTTATAAATTGGTGGTTAAATGA

Upstream 100 bases:

>100_bases
TTACTAATGTCATAGATGTAAAGCAAATGGCGACTGTAAAATTAAAAATAAGGTTTAATGGATAAACTAAAATACTGGAT
TATATTTTGAGGTGATAAAG

Downstream 100 bases:

>100_bases
TGAGGAGATTAAGATTTAAATCGTTAACAATGAGGATATGGACAACATTCACTGCTATAATTTTAATAATAATATGTAGT
ATTTCATTTTTATATTTAGT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MGRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIERIKDVPDLWILDIMLPDIDGYQIIKAVKENNKNTPVIFMS
ARNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERIYGKSNNSMDIITNIGEYKISKRQRAVFFGEKEIQLTNKEF
ELLNFFVENRNNVISREQILISIWGDDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK

Sequences:

>Translated_224_residues
MGRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIERIKDVPDLWILDIMLPDIDGYQIIKAVKENNKNTPVIFMS
ARNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERIYGKSNNSMDIITNIGEYKISKRQRAVFFGEKEIQLTNKEF
ELLNFFVENRNNVISREQILISIWGDDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK
>Mature_223_residues
GRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIERIKDVPDLWILDIMLPDIDGYQIIKAVKENNKNTPVIFMSA
RNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERIYGKSNNSMDIITNIGEYKISKRQRAVFFGEKEIQLTNKEFE
LLNFFVENRNNVISREQILISIWGDDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK

Specific function: Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=35.8744394618834, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=35.3448275862069, Blast_Score=146, Evalue=9e-37,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=32.6086956521739, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=33.3333333333333, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=36.5957446808511, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=35.2173913043478, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=32.8947368421053, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=33.6283185840708, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=30.5936073059361, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=31.2775330396476, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=30.7359307359307, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=31.2217194570136, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=27.6018099547511, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI145693140, Length=211, Percent_Identity=29.3838862559242, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790299, Length=101, Percent_Identity=35.6435643564356, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788550, Length=102, Percent_Identity=32.3529411764706, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787487, Length=129, Percent_Identity=28.6821705426357, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26328; Mature: 26197

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIERIKDVPDLWILDIMLPDIDG
CCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCEEEEEEECCCCCH
YQIIKAVKENNKNTPVIFMSARNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERI
HHHHHHHHHCCCCCCEEEEECCCCCHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
YGKSNNSMDIITNIGEYKISKRQRAVFFGEKEIQLTNKEFELLNFFVENRNNVISREQIL
HCCCCCCEEEEECCCHHHHCCCCEEEEECCCEEEEECHHHHHHHHHHHCCCCEECCEEEE
ISIWGDDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK
EEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHEEECCCEEEEEC
>Mature Secondary Structure 
GRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIERIKDVPDLWILDIMLPDIDG
CCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCEEEEEEECCCCCH
YQIIKAVKENNKNTPVIFMSARNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERI
HHHHHHHHHCCCCCCEEEEECCCCCHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
YGKSNNSMDIITNIGEYKISKRQRAVFFGEKEIQLTNKEFELLNFFVENRNNVISREQIL
HCCCCCCEEEEECCCHHHHCCCCEEEEECCCEEEEECHHHHHHHHHHHCCCCEECCEEEE
ISIWGDDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK
EEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9639930; 9384377; 11555295 [H]