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The map label for this gene is resA [H]

Identifier: 226947488

GI number: 226947488

Start: 306259

End: 306825

Strand: Direct

Name: resA [H]

Synonym: CLM_0322

Alternate gene names: 226947488

Gene position: 306259-306825 (Clockwise)

Preceding gene: 226947487

Following gene: 226947489

Centisome position: 7.37

GC content: 27.16

Gene sequence:

>567_bases
TTGAAAAATAATAAAAGATATATATATATAAGTGTTATAATGTTAGTTTTACTTGTAGGGGTCAAATTTGGATATGATTA
TTTATCAAATAATTACAAAAGTAATGAAGCTATTAATAATGTATCAGATAAAAATTCTAGTTTTCAGCCAGCAGTAGATT
TTACAGTTTATGATAAAGATAATAATGAAGTAAAGTTATCAGATTATAAAGGGAAGAAGGCTGTAGTAGTAAATTTCTGG
GCAAGCTGGTGTTCTCCATGTAAGTATGAGATGCCACATTTTCAAGAAGCAACAAATAAATATAATAATGAGGATTTAGA
AATACTAATGGTAAATCTTACAGACGGAATGAGGGAAACCAAAGGGTCCGCAGAGGGATTTATGAAAGAAGAAGGTTATA
ATATGAACGTGATGTTTGATATAAATCTTGATGCAGCTAATAAATATCAATTAAATGCTATTCCAAGAACAGTATTTATA
GATAAAGAAGGAAATTTGGTGTATGATCATGTAGGAATCATTGATAAAGAAATACTTGATGAAAATATAAATAAGATAAT
TAATTAA

Upstream 100 bases:

>100_bases
AGGGGGGCTGCTAATTATTATAGGGATAATGATGATGACTGGTTACCTAAACTTATTATTATCGATATTGGCATTTTAAA
TTATAAAAGGAGCGATAAAT

Downstream 100 bases:

>100_bases
GTACTCATATGGAGGTATAATTTTATGAAAGAAACTATACTTGTTATAGATGATGAAGTTAAGATAATAGAAGTTATAAA
ATTGTATTTAGAAAATGAGG

Product: antioxidant, AhpC/TSA family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MKNNKRYIYISVIMLVLLVGVKFGYDYLSNNYKSNEAINNVSDKNSSFQPAVDFTVYDKDNNEVKLSDYKGKKAVVVNFW
ASWCSPCKYEMPHFQEATNKYNNEDLEILMVNLTDGMRETKGSAEGFMKEEGYNMNVMFDINLDAANKYQLNAIPRTVFI
DKEGNLVYDHVGIIDKEILDENINKIIN

Sequences:

>Translated_188_residues
MKNNKRYIYISVIMLVLLVGVKFGYDYLSNNYKSNEAINNVSDKNSSFQPAVDFTVYDKDNNEVKLSDYKGKKAVVVNFW
ASWCSPCKYEMPHFQEATNKYNNEDLEILMVNLTDGMRETKGSAEGFMKEEGYNMNVMFDINLDAANKYQLNAIPRTVFI
DKEGNLVYDHVGIIDKEILDENINKIIN
>Mature_188_residues
MKNNKRYIYISVIMLVLLVGVKFGYDYLSNNYKSNEAINNVSDKNSSFQPAVDFTVYDKDNNEVKLSDYKGKKAVVVNFW
ASWCSPCKYEMPHFQEATNKYNNEDLEILMVNLTDGMRETKGSAEGFMKEEGYNMNVMFDINLDAANKYQLNAIPRTVFI
DKEGNLVYDHVGIIDKEILDENINKIIN

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 21691; Mature: 21691

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNKRYIYISVIMLVLLVGVKFGYDYLSNNYKSNEAINNVSDKNSSFQPAVDFTVYDKD
CCCCCEEEEHHHHHHHHHHHHHCCHHHHCCCCCCCHHHCCCCCCCCCCCCEEEEEEEECC
NNEVKLSDYKGKKAVVVNFWASWCSPCKYEMPHFQEATNKYNNEDLEILMVNLTDGMRET
CCEEEEECCCCCEEEEEEEHHHHCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCHHHC
KGSAEGFMKEEGYNMNVMFDINLDAANKYQLNAIPRTVFIDKEGNLVYDHVGIIDKEILD
CCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCEEEEEECCCCEEEEECCCHHHHHHH
ENINKIIN
HHHHHHCC
>Mature Secondary Structure
MKNNKRYIYISVIMLVLLVGVKFGYDYLSNNYKSNEAINNVSDKNSSFQPAVDFTVYDKD
CCCCCEEEEHHHHHHHHHHHHHCCHHHHCCCCCCCHHHCCCCCCCCCCCCEEEEEEEECC
NNEVKLSDYKGKKAVVVNFWASWCSPCKYEMPHFQEATNKYNNEDLEILMVNLTDGMRET
CCEEEEECCCCCEEEEEEEHHHHCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCHHHC
KGSAEGFMKEEGYNMNVMFDINLDAANKYQLNAIPRTVFIDKEGNLVYDHVGIIDKEILD
CCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCEEEEEECCCCEEEEECCCHHHHHHH
ENINKIIN
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA