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The map label for this gene is adhR [H]

Identifier: 226225139

GI number: 226225139

Start: 2648754

End: 2649176

Strand: Reverse

Name: adhR [H]

Synonym: Lm4b_02560

Alternate gene names: 226225139

Gene position: 2649176-2648754 (Counterclockwise)

Preceding gene: 226225140

Following gene: 226225138

Centisome position: 90.95

GC content: 40.9

Gene sequence:

>423_bases
ATGAATATCAAACAAGCGGCTGATATGTTTGGTTTAACAGTAGATACGTTGCGTTATTATGAGCGGGTCGGTGTTATTCC
GCCAGTCCATCGTAACGAAAGTGGTTACCGGGACTATAAAACGAGTGACTTGAACTGGGTTTATCTCGTGAAGAATTTAC
GGAATGCGGGATTATCGGTAGAATCGTTAATTGAGTTTGCGACACTTGCGCAGCTCAGAGAGACGCAAAATGTCGAAGCG
GCGCAAAAACAAGTACTGGTTGACCAACTAAAAGAATTAGACGAAAAATTAGCCGAGATGAAGAAGGTCAGAGAACTACT
CGTGTACAAAATCGATTCGTACGATAGTCACATTGCGCAGTTTAAAGCTGGCGAATTAAATGCAGATAATGTAGAAAAAT
TATGGAAACGGGACAAATTTTAA

Upstream 100 bases:

>100_bases
TTTTTTCTTTTCTCAAAAAAATAAACTCAAATTCCTTGCCTTGGTGTGAACTCCAGGGTTTATAATTCTATATGTAAAGA
ACGAAACGAGGTGATGGAGG

Downstream 100 bases:

>100_bases
AGATAAGAGGAGGATTTTCAAATGAAAACAGTGAAATTAAACAATGGTGTAGAAGTACCTATTTTAGGATTTGGGACATA
TCAAATTACAGATGCTGCTG

Product: transcription regulator (MerR family)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MNIKQAADMFGLTVDTLRYYERVGVIPPVHRNESGYRDYKTSDLNWVYLVKNLRNAGLSVESLIEFATLAQLRETQNVEA
AQKQVLVDQLKELDEKLAEMKKVRELLVYKIDSYDSHIAQFKAGELNADNVEKLWKRDKF

Sequences:

>Translated_140_residues
MNIKQAADMFGLTVDTLRYYERVGVIPPVHRNESGYRDYKTSDLNWVYLVKNLRNAGLSVESLIEFATLAQLRETQNVEA
AQKQVLVDQLKELDEKLAEMKKVRELLVYKIDSYDSHIAQFKAGELNADNVEKLWKRDKF
>Mature_140_residues
MNIKQAADMFGLTVDTLRYYERVGVIPPVHRNESGYRDYKTSDLNWVYLVKNLRNAGLSVESLIEFATLAQLRETQNVEA
AQKQVLVDQLKELDEKLAEMKKVRELLVYKIDSYDSHIAQFKAGELNADNVEKLWKRDKF

Specific function: Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon, the yraC and its own promoter region; binding is unchanged in the presence of aldehydes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=108, Percent_Identity=30.5555555555556, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16283; Mature: 16283

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKQAADMFGLTVDTLRYYERVGVIPPVHRNESGYRDYKTSDLNWVYLVKNLRNAGLSV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCH
ESLIEFATLAQLRETQNVEAAQKQVLVDQLKELDEKLAEMKKVRELLVYKIDSYDSHIAQ
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FKAGELNADNVEKLWKRDKF
HCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MNIKQAADMFGLTVDTLRYYERVGVIPPVHRNESGYRDYKTSDLNWVYLVKNLRNAGLSV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCH
ESLIEFATLAQLRETQNVEAAQKQVLVDQLKELDEKLAEMKKVRELLVYKIDSYDSHIAQ
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FKAGELNADNVEKLWKRDKF
HCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9384377 [H]