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The map label for this gene is atpD

Identifier: 226225077

GI number: 226225077

Start: 2578863

End: 2580284

Strand: Reverse

Name: atpD

Synonym: Lm4b_02498

Alternate gene names: 226225077

Gene position: 2580284-2578863 (Counterclockwise)

Preceding gene: 226225078

Following gene: 226225076

Centisome position: 88.59

GC content: 40.72

Gene sequence:

>1422_bases
ATGTCTAAAGGACAAGTAATCCAAGTTATGGGTCCAGTTGTAGACGTTAAATTTGAAGGTGGAAACTTACCTGAAATCTA
CAATGCCCTAGTTATTGAATATAAATCTGATGCAGAAGAAGCACCAACTAGCCAACTTACTTTAGAAGTAGCCATCCAAT
TAGGTGATGACGTTGTTCGTACAATCGCAATGGCATCAACAGATGGTGTTCAAAGAGGTATGGAAGTTATTGATACTGGG
AGCCCAATTACAGTTCCTGTAGGTACAGTAACTCTTGGTCGTGTATTTAATGTATTAGGAAACACCATCGATTTGGACGA
ACCACTTCCAAGCGATATTAAACGTAACAAAATTCACCGCGAAGCTCCAACTTTCGATCAATTAGCAACAACAACAGAAA
TTCTTGAAACAGGAATTAAAGTAGTTGACTTGTTAGCGCCATACCTAAAAGGTGGTAAAATCGGACTGTTCGGTGGTGCG
GGTGTAGGTAAAACCGTTCTAATTCAAGAGCTTATCCATAATATCGCACAAGAACACGGTGGTATTTCAGTGTTCGCGGG
CGTTGGAGAACGTACTCGTGAAGGGAACGACCTTTACTTTGAAATGAAAGATTCTGGTGTTATTGAAAAAACAGCGATGG
TATTCGGTCAAATGAACGAGCCACCAGGTGCGCGTATGCGTGTTGCCTTAACTGGTTTAACAATTGCTGAATATTTCCGT
GATGAAGAACATCAAGATGTACTTTTATTCATTGATAATATTTTCCGTTTCACACAAGCTGGTTCAGAGGTTTCGGCTTT
ACTAGGTCGTATGCCATCTGCGGTAGGTTACCAACCAACCCTAGCTACTGAAATGGGTCAATTACAAGAACGTATTACAT
CTACTAACGTTGGATCCGTTACTTCTATCCAAGCGATTTATGTACCAGCCGATGACTATACTGACCCGGCTCCGGCTACA
ACTTTCGCCCATCTAGATGCAACAACTAACTTGGAACGTAAATTAACGGAACAAGGTATTTATCCAGCGGTAGATCCACT
TGCTTCTACATCTCGTGCGCTTTCTCCTGATATCGTTGGAGAAGAACACTATGCAGTAGCAACGGAAGTACAGCGTTTAT
TACAAAGATATAAAGAATTACAAGATATCATCGCAATCTTAGGTATGGATGAGTTATCTGACGAAGATAAACAATCCGTT
TCCCGTGCGCGTCGTGTACAATTCTTCTTATCACAAAATTTCCACGTTGCAGAACAATTTACAGGTCAAAAAGGTTCTTA
TGTTCCTGTTAAAGAAACAGTTAAAGGATTCAAAGACCTATTAGCCGGAAAATACGACCATATTCCTGAAGATGCATTCC
GTTCAGTTGGACGCATTGAGGATGTTCTTGAAAAAGCAAAAGACATGGGCGTTGAAGTCTGA

Upstream 100 bases:

>100_bases
AATTACCGAAATCGTCGGAGGAGCAGCCGCACTAGAATAGAAGTCGGCGTTTCTTGTAACGTCCCAATAAATGGGAAGGT
AAGTGAGGAGGAATAATTGC

Downstream 100 bases:

>100_bases
TAAAAACAGGAGGAAATACGTATGGGTTCATTAAATGTTAGTATTGTTACTCCAGACGGCCCTGTTTATGAAGGCGTTGC
TCAAATGGTTATTGCTAGAA

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta 2; F-ATPase subunit beta 2 [H]

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MSKGQVIQVMGPVVDVKFEGGNLPEIYNALVIEYKSDAEEAPTSQLTLEVAIQLGDDVVRTIAMASTDGVQRGMEVIDTG
SPITVPVGTVTLGRVFNVLGNTIDLDEPLPSDIKRNKIHREAPTFDQLATTTEILETGIKVVDLLAPYLKGGKIGLFGGA
GVGKTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYFEMKDSGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFR
DEEHQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTNVGSVTSIQAIYVPADDYTDPAPAT
TFAHLDATTNLERKLTEQGIYPAVDPLASTSRALSPDIVGEEHYAVATEVQRLLQRYKELQDIIAILGMDELSDEDKQSV
SRARRVQFFLSQNFHVAEQFTGQKGSYVPVKETVKGFKDLLAGKYDHIPEDAFRSVGRIEDVLEKAKDMGVEV

Sequences:

>Translated_473_residues
MSKGQVIQVMGPVVDVKFEGGNLPEIYNALVIEYKSDAEEAPTSQLTLEVAIQLGDDVVRTIAMASTDGVQRGMEVIDTG
SPITVPVGTVTLGRVFNVLGNTIDLDEPLPSDIKRNKIHREAPTFDQLATTTEILETGIKVVDLLAPYLKGGKIGLFGGA
GVGKTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYFEMKDSGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFR
DEEHQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTNVGSVTSIQAIYVPADDYTDPAPAT
TFAHLDATTNLERKLTEQGIYPAVDPLASTSRALSPDIVGEEHYAVATEVQRLLQRYKELQDIIAILGMDELSDEDKQSV
SRARRVQFFLSQNFHVAEQFTGQKGSYVPVKETVKGFKDLLAGKYDHIPEDAFRSVGRIEDVLEKAKDMGVEV
>Mature_472_residues
SKGQVIQVMGPVVDVKFEGGNLPEIYNALVIEYKSDAEEAPTSQLTLEVAIQLGDDVVRTIAMASTDGVQRGMEVIDTGS
PITVPVGTVTLGRVFNVLGNTIDLDEPLPSDIKRNKIHREAPTFDQLATTTEILETGIKVVDLLAPYLKGGKIGLFGGAG
VGKTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYFEMKDSGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRD
EEHQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTNVGSVTSIQAIYVPADDYTDPAPATT
FAHLDATTNLERKLTEQGIYPAVDPLASTSRALSPDIVGEEHYAVATEVQRLLQRYKELQDIIAILGMDELSDEDKQSVS
RARRVQFFLSQNFHVAEQFTGQKGSYVPVKETVKGFKDLLAGKYDHIPEDAFRSVGRIEDVLEKAKDMGVEV

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=477, Percent_Identity=66.0377358490566, Blast_Score=616, Evalue=1e-176,
Organism=Homo sapiens, GI19913424, Length=342, Percent_Identity=26.6081871345029, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI50345984, Length=374, Percent_Identity=26.4705882352941, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI4757810, Length=374, Percent_Identity=26.4705882352941, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI19913428, Length=342, Percent_Identity=24.8538011695906, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI19913426, Length=343, Percent_Identity=24.4897959183673, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI1790170, Length=469, Percent_Identity=62.6865671641791, Blast_Score=596, Evalue=1e-171,
Organism=Escherichia coli, GI1788251, Length=333, Percent_Identity=30.03003003003, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1790172, Length=430, Percent_Identity=25.8139534883721, Blast_Score=105, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=474, Percent_Identity=64.1350210970464, Blast_Score=598, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI17565854, Length=355, Percent_Identity=28.7323943661972, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17570191, Length=337, Percent_Identity=24.6290801186944, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17510931, Length=340, Percent_Identity=25, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988080, Length=401, Percent_Identity=25.6857855361596, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71988063, Length=401, Percent_Identity=25.6857855361596, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71988074, Length=353, Percent_Identity=24.929178470255, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322581, Length=465, Percent_Identity=68.1720430107527, Blast_Score=613, Evalue=1e-176,
Organism=Saccharomyces cerevisiae, GI6319603, Length=345, Percent_Identity=25.7971014492754, Blast_Score=103, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6319370, Length=378, Percent_Identity=26.984126984127, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6320016, Length=260, Percent_Identity=26.1538461538462, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24638766, Length=476, Percent_Identity=66.5966386554622, Blast_Score=620, Evalue=1e-178,
Organism=Drosophila melanogaster, GI28574560, Length=473, Percent_Identity=64.9048625792812, Blast_Score=592, Evalue=1e-169,
Organism=Drosophila melanogaster, GI20129479, Length=346, Percent_Identity=28.0346820809249, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24583988, Length=349, Percent_Identity=26.0744985673352, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24583986, Length=349, Percent_Identity=26.0744985673352, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24583984, Length=349, Percent_Identity=26.0744985673352, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24583992, Length=306, Percent_Identity=28.1045751633987, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI281361666, Length=388, Percent_Identity=24.2268041237113, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24646341, Length=388, Percent_Identity=24.2268041237113, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI17136796, Length=388, Percent_Identity=24.2268041237113, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24658560, Length=378, Percent_Identity=26.1904761904762, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24638768, Length=98, Percent_Identity=50, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 51609; Mature: 51478

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKGQVIQVMGPVVDVKFEGGNLPEIYNALVIEYKSDAEEAPTSQLTLEVAIQLGDDVVR
CCCCCEEEEECCEEEEEECCCCCHHHHHHHEEEECCCCCCCCCHHEEEEHEEHHCHHHHH
TIAMASTDGVQRGMEVIDTGSPITVPVGTVTLGRVFNVLGNTIDLDEPLPSDIKRNKIHR
HHHHHHHHHHHHCHHHHCCCCCCEEEECHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHC
EAPTFDQLATTTEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTVLIQELIHNIAQEHG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
GISVFAGVGERTREGNDLYFEMKDSGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFR
CEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHC
DEEHQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTNVGSV
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
TSIQAIYVPADDYTDPAPATTFAHLDATTNLERKLTEQGIYPAVDPLASTSRALSPDIVG
EEEEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHCCCCCCCCHHHHHHHCCCCCCCC
EEHYAVATEVQRLLQRYKELQDIIAILGMDELSDEDKQSVSRARRVQFFLSQNFHVAEQF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
TGQKGSYVPVKETVKGFKDLLAGKYDHIPEDAFRSVGRIEDVLEKAKDMGVEV
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SKGQVIQVMGPVVDVKFEGGNLPEIYNALVIEYKSDAEEAPTSQLTLEVAIQLGDDVVR
CCCCEEEEECCEEEEEECCCCCHHHHHHHEEEECCCCCCCCCHHEEEEHEEHHCHHHHH
TIAMASTDGVQRGMEVIDTGSPITVPVGTVTLGRVFNVLGNTIDLDEPLPSDIKRNKIHR
HHHHHHHHHHHHCHHHHCCCCCCEEEECHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHC
EAPTFDQLATTTEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTVLIQELIHNIAQEHG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
GISVFAGVGERTREGNDLYFEMKDSGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFR
CEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHC
DEEHQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTNVGSV
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
TSIQAIYVPADDYTDPAPATTFAHLDATTNLERKLTEQGIYPAVDPLASTSRALSPDIVG
EEEEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHCCCCCCCCHHHHHHHCCCCCCCC
EEHYAVATEVQRLLQRYKELQDIIAILGMDELSDEDKQSVSRARRVQFFLSQNFHVAEQF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
TGQKGSYVPVKETVKGFKDLLAGKYDHIPEDAFRSVGRIEDVLEKAKDMGVEV
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]