| Definition | Listeria monocytogenes Clip81459, complete genome. |
|---|---|
| Accession | NC_012488 |
| Length | 2,912,690 |
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The map label for this gene is yfnA [H]
Identifier: 226225017
GI number: 226225017
Start: 2515397
End: 2516788
Strand: Reverse
Name: yfnA [H]
Synonym: Lm4b_02438
Alternate gene names: 226225017
Gene position: 2516788-2515397 (Counterclockwise)
Preceding gene: 226225019
Following gene: 226225015
Centisome position: 86.41
GC content: 38.15
Gene sequence:
>1392_bases ATGACGAAAGTTAATTCTTTTTTCAGAAAAAAGAGTTTTCATAACCCAGCGACAGATAAACATCATCTGAACAAAACGTT AGGAGCGTTTGATTTAACGATGCTTGGAGTCGGAGCGGTTGTTGGGGGAGGAATATTTATTCTTCCAGGGCAGGTAGCTT CTGTCATTGCGGGACCAGGAATTATTATTTCTTTTATTATTGCGGGAATTGCTTGCTGTTTGGCGGCATTATGTTATTCG GAATTTGCTTCTAAATTACCAGTCGCAGGTAGCGCATATACTTACAGTTACCATGTGTTCGGGGAAGGTGTTGCATGGAT TTTAGGGTGGTCGCTGATTTTAGAATATGGTCTGGCTGTTGCTGCAATCGCAAGTGGTTGGTCTTCTTATATGAAGAGTC TACTAGCAGGATTTGACTTACATATTCCAACGGTGATTTCTTCAGCTTATGACCCGAGTGCCGGAACCTATTTTGACTTA CTTGCATTTGTAGTAGTTATGGTAATTGGTATTTTACTTAGTTTTGGTATTCGTGAATCCACACGAGTGAATAATATTAT GGTGTTAGTAAAAATTGCAGTGGTTGTATTATTTATTTTAGTAGGAGCTTTCTATGTGAAACCTGATAATTGGACGCCGT TCTTGCCGTTTGGTGTACAAGGAGTCATTACAGGAGCTTCCACAGTTTTCTTTGCTTATATCGGCTTTGATGCTGTATCA AGTGCCGCGGAAGAAGTGAAAAATCCACAAAAAAATATGCCAATAGGAATTATTTCTTCACTGGCAATCTGTACACTACT TTATATTTTACTTTCTGCAGTACTTACAGGGGTTGTTCCTTATACGGATTTAGTTGATGTTAGTGCACCAGTTGCTTTCG CGCTTCAAGCTATTAATCAAAACTGGATTGCGGGCTTGTTGTCAGTTGGTGCGATTGTTGGGATGACAACGGTTGTACTT GTTATGTCTTATGGTGGTACACGCTTGTTATTTGCAATGGGACGTGACGGATTATTACCAAAATCGTTCTCAAAAATAAG CAAAAATGATACACCTGTGAGAAATACGATGATTTTTGCGACAGTAATGGGACTAATTGCTTCTACTGTACCGATGGCAG ATTTAGCACAATTAATTAATATTGGTACGTTGTTTGCTTTTGCGATGGTTTCTATTGGGATTTTCTTTTTACGGAGAAAT CCAGACTTGAATCAAAAAGGATTTAGAACGCCATTTTATCCAGTAGTACCAGCACTTTCCTTTTTGCTTTGTGTATATTT AATGATTAACTTATCTAAAACAACATGGATTGCATTCGGTATTTGGTTTGTGATAGGAATACTAGTGTATACATTCTACG GAAGAAAACATTCAGCGCTTCGTGTAAAATAA
Upstream 100 bases:
>100_bases TTCAATCTATTTATGGTACTATGAATAATAGTTTTCAAGTTAGTTTAAAAATACACATATAAATTAACTGAAAATTGGAA TTTAAGAAGGAGGAATTTTT
Downstream 100 bases:
>100_bases AGTATAAAAAAAGAGGTTTTGCATTTTGTGCAAAACCTCTTTTTTTTATTAGCCTTTTAAGCCAGATTTGTTAATGATGA TATCATCAATTAAGCCGTAA
Product: amino acid transporter
Products: Proton [Cytoplasm]; L-lysine [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 463; Mature: 462
Protein sequence:
>463_residues MTKVNSFFRKKSFHNPATDKHHLNKTLGAFDLTMLGVGAVVGGGIFILPGQVASVIAGPGIIISFIIAGIACCLAALCYS EFASKLPVAGSAYTYSYHVFGEGVAWILGWSLILEYGLAVAAIASGWSSYMKSLLAGFDLHIPTVISSAYDPSAGTYFDL LAFVVVMVIGILLSFGIRESTRVNNIMVLVKIAVVVLFILVGAFYVKPDNWTPFLPFGVQGVITGASTVFFAYIGFDAVS SAAEEVKNPQKNMPIGIISSLAICTLLYILLSAVLTGVVPYTDLVDVSAPVAFALQAINQNWIAGLLSVGAIVGMTTVVL VMSYGGTRLLFAMGRDGLLPKSFSKISKNDTPVRNTMIFATVMGLIASTVPMADLAQLINIGTLFAFAMVSIGIFFLRRN PDLNQKGFRTPFYPVVPALSFLLCVYLMINLSKTTWIAFGIWFVIGILVYTFYGRKHSALRVK
Sequences:
>Translated_463_residues MTKVNSFFRKKSFHNPATDKHHLNKTLGAFDLTMLGVGAVVGGGIFILPGQVASVIAGPGIIISFIIAGIACCLAALCYS EFASKLPVAGSAYTYSYHVFGEGVAWILGWSLILEYGLAVAAIASGWSSYMKSLLAGFDLHIPTVISSAYDPSAGTYFDL LAFVVVMVIGILLSFGIRESTRVNNIMVLVKIAVVVLFILVGAFYVKPDNWTPFLPFGVQGVITGASTVFFAYIGFDAVS SAAEEVKNPQKNMPIGIISSLAICTLLYILLSAVLTGVVPYTDLVDVSAPVAFALQAINQNWIAGLLSVGAIVGMTTVVL VMSYGGTRLLFAMGRDGLLPKSFSKISKNDTPVRNTMIFATVMGLIASTVPMADLAQLINIGTLFAFAMVSIGIFFLRRN PDLNQKGFRTPFYPVVPALSFLLCVYLMINLSKTTWIAFGIWFVIGILVYTFYGRKHSALRVK >Mature_462_residues TKVNSFFRKKSFHNPATDKHHLNKTLGAFDLTMLGVGAVVGGGIFILPGQVASVIAGPGIIISFIIAGIACCLAALCYSE FASKLPVAGSAYTYSYHVFGEGVAWILGWSLILEYGLAVAAIASGWSSYMKSLLAGFDLHIPTVISSAYDPSAGTYFDLL AFVVVMVIGILLSFGIRESTRVNNIMVLVKIAVVVLFILVGAFYVKPDNWTPFLPFGVQGVITGASTVFFAYIGFDAVSS AAEEVKNPQKNMPIGIISSLAICTLLYILLSAVLTGVVPYTDLVDVSAPVAFALQAINQNWIAGLLSVGAIVGMTTVVLV MSYGGTRLLFAMGRDGLLPKSFSKISKNDTPVRNTMIFATVMGLIASTVPMADLAQLINIGTLFAFAMVSIGIFFLRRNP DLNQKGFRTPFYPVVPALSFLLCVYLMINLSKTTWIAFGIWFVIGILVYTFYGRKHSALRVK
Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of Lysine. [C]
COG id: COG0531
COG function: function code E; Amino acid transporters
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]
Homologues:
Organism=Homo sapiens, GI258645169, Length=435, Percent_Identity=33.7931034482759, Blast_Score=241, Evalue=1e-63, Organism=Homo sapiens, GI181337167, Length=401, Percent_Identity=36.6583541147132, Blast_Score=237, Evalue=2e-62, Organism=Homo sapiens, GI258614005, Length=436, Percent_Identity=33.7155963302752, Blast_Score=234, Evalue=2e-61, Organism=Homo sapiens, GI258614003, Length=436, Percent_Identity=33.7155963302752, Blast_Score=233, Evalue=3e-61, Organism=Homo sapiens, GI4507047, Length=431, Percent_Identity=33.4106728538283, Blast_Score=226, Evalue=5e-59, Organism=Homo sapiens, GI114326544, Length=439, Percent_Identity=32.5740318906606, Blast_Score=223, Evalue=2e-58, Organism=Homo sapiens, GI114326550, Length=439, Percent_Identity=32.5740318906606, Blast_Score=223, Evalue=2e-58, Organism=Homo sapiens, GI110347453, Length=396, Percent_Identity=34.5959595959596, Blast_Score=217, Evalue=2e-56, Organism=Homo sapiens, GI186910308, Length=435, Percent_Identity=27.1264367816092, Blast_Score=114, Evalue=1e-25, Organism=Homo sapiens, GI186910306, Length=435, Percent_Identity=27.1264367816092, Blast_Score=114, Evalue=1e-25, Organism=Homo sapiens, GI186910304, Length=435, Percent_Identity=27.1264367816092, Blast_Score=114, Evalue=1e-25, Organism=Homo sapiens, GI187423910, Length=464, Percent_Identity=25.6465517241379, Blast_Score=102, Evalue=6e-22, Organism=Homo sapiens, GI7657591, Length=464, Percent_Identity=25.6465517241379, Blast_Score=102, Evalue=6e-22, Organism=Homo sapiens, GI115648063, Length=437, Percent_Identity=25.858123569794, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI115648022, Length=437, Percent_Identity=25.858123569794, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI71979932, Length=437, Percent_Identity=26.7734553775744, Blast_Score=82, Evalue=1e-15, Organism=Homo sapiens, GI33286428, Length=412, Percent_Identity=24.7572815533981, Blast_Score=82, Evalue=1e-15, Organism=Homo sapiens, GI7657683, Length=396, Percent_Identity=23.2323232323232, Blast_Score=73, Evalue=6e-13, Organism=Homo sapiens, GI71999149, Length=405, Percent_Identity=22.962962962963, Blast_Score=72, Evalue=1e-12, Organism=Homo sapiens, GI9790235, Length=344, Percent_Identity=23.546511627907, Blast_Score=67, Evalue=3e-11, Organism=Escherichia coli, GI1788480, Length=460, Percent_Identity=25.2173913043478, Blast_Score=120, Evalue=1e-28, Organism=Escherichia coli, GI87082023, Length=463, Percent_Identity=28.0777537796976, Blast_Score=107, Evalue=2e-24, Organism=Escherichia coli, GI1786302, Length=428, Percent_Identity=23.5981308411215, Blast_Score=101, Evalue=1e-22, Organism=Escherichia coli, GI87081708, Length=443, Percent_Identity=21.8961625282167, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI87081869, Length=457, Percent_Identity=26.6958424507659, Blast_Score=96, Evalue=5e-21, Organism=Escherichia coli, GI87082250, Length=471, Percent_Identity=23.7791932059448, Blast_Score=85, Evalue=1e-17, Organism=Escherichia coli, GI1786789, Length=425, Percent_Identity=21.1764705882353, Blast_Score=84, Evalue=2e-17, Organism=Escherichia coli, GI1790653, Length=485, Percent_Identity=21.2371134020619, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI2367353, Length=464, Percent_Identity=25, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1786694, Length=392, Percent_Identity=24.234693877551, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1786908, Length=340, Percent_Identity=23.5294117647059, Blast_Score=77, Evalue=2e-15, Organism=Escherichia coli, GI87081915, Length=358, Percent_Identity=20.1117318435754, Blast_Score=75, Evalue=1e-14, Organism=Escherichia coli, GI1786602, Length=466, Percent_Identity=22.3175965665236, Blast_Score=71, Evalue=2e-13, Organism=Escherichia coli, GI1789017, Length=351, Percent_Identity=21.3675213675214, Blast_Score=69, Evalue=6e-13, Organism=Escherichia coli, GI1790575, Length=454, Percent_Identity=21.5859030837004, Blast_Score=66, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17532491, Length=411, Percent_Identity=37.4695863746959, Blast_Score=263, Evalue=2e-70, Organism=Caenorhabditis elegans, GI17531343, Length=414, Percent_Identity=35.9903381642512, Blast_Score=241, Evalue=5e-64, Organism=Caenorhabditis elegans, GI17533459, Length=409, Percent_Identity=36.919315403423, Blast_Score=237, Evalue=8e-63, Organism=Caenorhabditis elegans, GI17568033, Length=370, Percent_Identity=23.7837837837838, Blast_Score=89, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17540018, Length=437, Percent_Identity=25.4004576659039, Blast_Score=89, Evalue=6e-18, Organism=Caenorhabditis elegans, GI71982608, Length=436, Percent_Identity=22.2477064220184, Blast_Score=86, Evalue=5e-17, Organism=Caenorhabditis elegans, GI71982612, Length=436, Percent_Identity=22.2477064220184, Blast_Score=86, Evalue=5e-17, Organism=Caenorhabditis elegans, GI32566699, Length=311, Percent_Identity=25.08038585209, Blast_Score=85, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17537453, Length=322, Percent_Identity=24.5341614906832, Blast_Score=82, Evalue=7e-16, Organism=Caenorhabditis elegans, GI32566695, Length=422, Percent_Identity=24.6445497630332, Blast_Score=82, Evalue=8e-16, Organism=Caenorhabditis elegans, GI193208714, Length=422, Percent_Identity=24.6445497630332, Blast_Score=81, Evalue=1e-15, Organism=Caenorhabditis elegans, GI71993915, Length=415, Percent_Identity=21.2048192771084, Blast_Score=79, Evalue=4e-15, Organism=Caenorhabditis elegans, GI71995382, Length=418, Percent_Identity=22.0095693779904, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI71995388, Length=399, Percent_Identity=22.3057644110276, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI71990446, Length=442, Percent_Identity=23.3031674208145, Blast_Score=69, Evalue=5e-12, Organism=Caenorhabditis elegans, GI71982623, Length=264, Percent_Identity=21.969696969697, Blast_Score=68, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6321629, Length=457, Percent_Identity=21.0065645514223, Blast_Score=67, Evalue=5e-12, Organism=Drosophila melanogaster, GI24667468, Length=406, Percent_Identity=39.4088669950739, Blast_Score=285, Evalue=3e-77, Organism=Drosophila melanogaster, GI24666159, Length=417, Percent_Identity=37.1702637889688, Blast_Score=279, Evalue=3e-75, Organism=Drosophila melanogaster, GI221512776, Length=417, Percent_Identity=37.1702637889688, Blast_Score=279, Evalue=3e-75, Organism=Drosophila melanogaster, GI24668806, Length=430, Percent_Identity=36.046511627907, Blast_Score=259, Evalue=3e-69, Organism=Drosophila melanogaster, GI21356285, Length=430, Percent_Identity=36.046511627907, Blast_Score=259, Evalue=3e-69, Organism=Drosophila melanogaster, GI24668802, Length=430, Percent_Identity=36.046511627907, Blast_Score=259, Evalue=3e-69, Organism=Drosophila melanogaster, GI281366235, Length=408, Percent_Identity=36.7647058823529, Blast_Score=234, Evalue=1e-61, Organism=Drosophila melanogaster, GI116007820, Length=408, Percent_Identity=36.7647058823529, Blast_Score=234, Evalue=1e-61, Organism=Drosophila melanogaster, GI116007818, Length=408, Percent_Identity=36.7647058823529, Blast_Score=230, Evalue=2e-60, Organism=Drosophila melanogaster, GI85725152, Length=408, Percent_Identity=36.7647058823529, Blast_Score=230, Evalue=2e-60, Organism=Drosophila melanogaster, GI161077963, Length=412, Percent_Identity=35.6796116504854, Blast_Score=216, Evalue=2e-56, Organism=Drosophila melanogaster, GI21357367, Length=427, Percent_Identity=23.6533957845433, Blast_Score=102, Evalue=7e-22, Organism=Drosophila melanogaster, GI221331183, Length=482, Percent_Identity=25.5186721991701, Blast_Score=89, Evalue=7e-18, Organism=Drosophila melanogaster, GI17647653, Length=482, Percent_Identity=25.5186721991701, Blast_Score=89, Evalue=7e-18, Organism=Drosophila melanogaster, GI24664379, Length=482, Percent_Identity=25.5186721991701, Blast_Score=89, Evalue=7e-18, Organism=Drosophila melanogaster, GI24641995, Length=347, Percent_Identity=25.9365994236311, Blast_Score=81, Evalue=2e-15, Organism=Drosophila melanogaster, GI24641993, Length=347, Percent_Identity=25.9365994236311, Blast_Score=81, Evalue=2e-15, Organism=Drosophila melanogaster, GI45550968, Length=474, Percent_Identity=24.6835443037975, Blast_Score=74, Evalue=3e-13, Organism=Drosophila melanogaster, GI19921172, Length=474, Percent_Identity=24.6835443037975, Blast_Score=74, Evalue=3e-13, Organism=Drosophila melanogaster, GI24651635, Length=391, Percent_Identity=22.7621483375959, Blast_Score=74, Evalue=3e-13, Organism=Drosophila melanogaster, GI24651633, Length=391, Percent_Identity=22.7621483375959, Blast_Score=74, Evalue=3e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004841 - InterPro: IPR002293 - InterPro: IPR015606 [H]
Pfam domain/function: PF00324 AA_permease [H]
EC number: NA
Molecular weight: Translated: 49756; Mature: 49624
Theoretical pI: Translated: 9.53; Mature: 9.53
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTKVNSFFRKKSFHNPATDKHHLNKTLGAFDLTMLGVGAVVGGGIFILPGQVASVIAGPG CCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHCCCH IIISFIIAGIACCLAALCYSEFASKLPVAGSAYTYSYHVFGEGVAWILGWSLILEYGLAV HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHH AAIASGWSSYMKSLLAGFDLHIPTVISSAYDPSAGTYFDLLAFVVVMVIGILLSFGIRES HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC TRVNNIMVLVKIAVVVLFILVGAFYVKPDNWTPFLPFGVQGVITGASTVFFAYIGFDAVS CHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH SAAEEVKNPQKNMPIGIISSLAICTLLYILLSAVLTGVVPYTDLVDVSAPVAFALQAINQ HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHH NWIAGLLSVGAIVGMTTVVLVMSYGGTRLLFAMGRDGLLPKSFSKISKNDTPVRNTMIFA HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHH TVMGLIASTVPMADLAQLINIGTLFAFAMVSIGIFFLRRNPDLNQKGFRTPFYPVVPALS HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHH FLLCVYLMINLSKTTWIAFGIWFVIGILVYTFYGRKHSALRVK HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECC >Mature Secondary Structure TKVNSFFRKKSFHNPATDKHHLNKTLGAFDLTMLGVGAVVGGGIFILPGQVASVIAGPG CCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHCCCH IIISFIIAGIACCLAALCYSEFASKLPVAGSAYTYSYHVFGEGVAWILGWSLILEYGLAV HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHH AAIASGWSSYMKSLLAGFDLHIPTVISSAYDPSAGTYFDLLAFVVVMVIGILLSFGIRES HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC TRVNNIMVLVKIAVVVLFILVGAFYVKPDNWTPFLPFGVQGVITGASTVFFAYIGFDAVS CHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH SAAEEVKNPQKNMPIGIISSLAICTLLYILLSAVLTGVVPYTDLVDVSAPVAFALQAINQ HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHH NWIAGLLSVGAIVGMTTVVLVMSYGGTRLLFAMGRDGLLPKSFSKISKNDTPVRNTMIFA HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHH TVMGLIASTVPMADLAQLINIGTLFAFAMVSIGIFFLRRNPDLNQKGFRTPFYPVVPALS HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHH FLLCVYLMINLSKTTWIAFGIWFVIGILVYTFYGRKHSALRVK HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Proton [Periplasm]; L-lysine [Periplasm] [C]
Specific reaction: Proton [Periplasm] + L-lysine [Periplasm] = Proton [Cytoplasm] + L-lysine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9141694; 9384377 [H]