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The map label for this gene is 226225011

Identifier: 226225011

GI number: 226225011

Start: 2509079

End: 2511241

Strand: Reverse

Name: 226225011

Synonym: Lm4b_02432

Alternate gene names: NA

Gene position: 2511241-2509079 (Counterclockwise)

Preceding gene: 226225012

Following gene: 226225010

Centisome position: 86.22

GC content: 41.33

Gene sequence:

>2163_bases
ATGAAAGATGGATTTTTAAGTAAAATTGCCAGTGGGGTTGGTGGCAAGAAAGGCCGGTTTATAACATTAGGTATTTGGAT
TATCGCAATTATTATTTTACAGTTTTTCTTTCCAAAAGCAGCTGATTACAAAGATGACGCTGCGAAAGATTTACCGAATT
CAGAGCCTTCTGTTGTCGCCCAAAAACTCATTGACGACAAATTTGCTGGAACGGACGGGGTACCAGCGCTTATCACTTGG
TATCGTTCAACTGGTTTAACAACCGAAGACTTAGTTAATATTCAAAAATACAGCAAAGAATTGACCGAAAACCCGGTAGA
CTATCAAAAAATGGCGGTTCCTTACGATAAAATGCCACCCGTGGCGCTCAAACAACAAGTTTCTAAAGACGGAACTACTT
TTATTCAAACCGTTATTATGAAAGACAGTGCGACTTCAGATCAACTAACAGAGAGCTTCAAGCAACTTGAATCAGCGGCT
AAAACAACCATTGGAGAAAATCCATTTGCACAGAAAGTATCTGCTGATGATGCGCTTGTTGCTCGGACAACTGGACCGGC
TGGTATTAGCGTGGATGCGAGTGGACTATTTAAAGATGCGGATGTTTCGCTGCTAATCGGAACAGTACTACTTGTTTTAG
TCTTTTTACTAGTAATTTATCGTTCGCCAATTTTAGCGTTAATTCCTTTGATTGCAGTCGGTTTTGCCTACTTAGTAATT
ACGCCGATTCTTGGGTTACTCGCGAAAGAAGGTATTATCACATATGGCTCACAAGGGCTCTCGATAATGACCGTATTACT
ATTTGGCGCCGGAACGGATTATTGTTTATTCTTAATATCCAGATTCCGCAGCCATCTGCACACAGAGAAAAACAGATTCC
AAGCATTTAAAGAAGCATTTAGCGGAACAGCCGGCGCAATTGCACTTAGTGGATTGACCGTAATGACCGCACTACTTCTA
TTATTAGCAGCAGAATATGGTTCATTCCACAATTTCGCCGTACCATTTAGTTTAGCGATTTTCATTATGATGATTTCCTC
GCTAACACTTGTCCCAGCACTTCTAGGCATATTCGGTCGTGTGTCATTCTGGCCATTTGTCCCAAGAACCGTAGAAATGG
AAGAAACACGCGCGAAGAAAAAAGGCAAAACACCAAAACACCACAAAGAAAACCGTTTTTGGCATAAAATTGGTGAAATG
TCTGCGAAACATCCTGTACGAATTTTAATTATCACATTGATTATTTTAATTGGATGTGGGATTTTTACAACTCAGGTGAA
ATACACGTATGACACACTTTCAACATTCCCAGAAGATATGCCATCTCGGGAAGGATTTACCTTAATTAGTGATCATTTTG
GTGCCGGTATGCTTGCGCCAATGGAAGTAGTGGTAAACTCCAAAGAATCAATGAAGAGTTCGCTTGAAAATGTGGATGGA
GTGGCTTCAGTGACTGGTCCAGAACGAAGCAAAGGTTATCAAAAATATACACTTATTTTAAAAGATAACCCTTATAGCAA
TGAAGCAATGGATGTCGTTCCAAAAGTACGTGCCGCAGCCGACAAAGGAAATGACGTATATATTGCGGGACAAACTGCGA
CACAATATGATGATCGCGCGGTGACAGAGCACGATGAAAAAGTGATTATTCCGCTTGTTATCGCTTTGATTGCGATTTTA
CTTTTATGCTACTTGCGCTCGATTACAGCAATGCTTTACTTAGTCGCTACAGTTCTCTTGTCCTTCGTTGGAGCGCTCGG
CCTTGGTTGGGTCATCATTCATTACGCGATGGGAGTAGAGGCGATTTCTGGCTTAATTCCTCTCTATGCCTTTGTTTTCA
TCGTCGCACTCGGGGAAGATTACAATATCTTTATGATTTCTAGTATTTGGAAAAACAGCAAGAAAATGCCACTTAGAAAA
GCGATTACAGAAGGTGTTGGCCAAACTGGCGGGGTTATCACGTCTGCTGGTTTAATTTTAGCAGGAACTTTCGGAGTCCT
AACTACACTGCCAATTCAGCTCTTAGTACAATTTGGCTTAATTACGGCAATTGGTGTCCTACTCGATACCTTCATCGTCC
GCCCGTTCCTAGTTCCATCAATTACTGTGCTCCTTGGAAAATGGGCGTTCTGGCCAGGTAAACAGCATAAGATGACAAAA
TGA

Upstream 100 bases:

>100_bases
ATATGTAAAAAAGAGGTATAATTTAGCGTGCTTCTTTTTTTGGTGTTTCACTTATCGAATGATAAACGAAAAAAATAAGC
AAACTAAAGGGGGATTTATA

Downstream 100 bases:

>100_bases
AAACGACTTTGAAAAATCTCTTGTCTATTCCTCTGAAAAGTATATAATAGATGTATCTAAAAGGAGGAACGACAGAAAAT
GAGAGTAATTGATACCCACT

Product: transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 720; Mature: 720

Protein sequence:

>720_residues
MKDGFLSKIASGVGGKKGRFITLGIWIIAIIILQFFFPKAADYKDDAAKDLPNSEPSVVAQKLIDDKFAGTDGVPALITW
YRSTGLTTEDLVNIQKYSKELTENPVDYQKMAVPYDKMPPVALKQQVSKDGTTFIQTVIMKDSATSDQLTESFKQLESAA
KTTIGENPFAQKVSADDALVARTTGPAGISVDASGLFKDADVSLLIGTVLLVLVFLLVIYRSPILALIPLIAVGFAYLVI
TPILGLLAKEGIITYGSQGLSIMTVLLFGAGTDYCLFLISRFRSHLHTEKNRFQAFKEAFSGTAGAIALSGLTVMTALLL
LLAAEYGSFHNFAVPFSLAIFIMMISSLTLVPALLGIFGRVSFWPFVPRTVEMEETRAKKKGKTPKHHKENRFWHKIGEM
SAKHPVRILIITLIILIGCGIFTTQVKYTYDTLSTFPEDMPSREGFTLISDHFGAGMLAPMEVVVNSKESMKSSLENVDG
VASVTGPERSKGYQKYTLILKDNPYSNEAMDVVPKVRAAADKGNDVYIAGQTATQYDDRAVTEHDEKVIIPLVIALIAIL
LLCYLRSITAMLYLVATVLLSFVGALGLGWVIIHYAMGVEAISGLIPLYAFVFIVALGEDYNIFMISSIWKNSKKMPLRK
AITEGVGQTGGVITSAGLILAGTFGVLTTLPIQLLVQFGLITAIGVLLDTFIVRPFLVPSITVLLGKWAFWPGKQHKMTK

Sequences:

>Translated_720_residues
MKDGFLSKIASGVGGKKGRFITLGIWIIAIIILQFFFPKAADYKDDAAKDLPNSEPSVVAQKLIDDKFAGTDGVPALITW
YRSTGLTTEDLVNIQKYSKELTENPVDYQKMAVPYDKMPPVALKQQVSKDGTTFIQTVIMKDSATSDQLTESFKQLESAA
KTTIGENPFAQKVSADDALVARTTGPAGISVDASGLFKDADVSLLIGTVLLVLVFLLVIYRSPILALIPLIAVGFAYLVI
TPILGLLAKEGIITYGSQGLSIMTVLLFGAGTDYCLFLISRFRSHLHTEKNRFQAFKEAFSGTAGAIALSGLTVMTALLL
LLAAEYGSFHNFAVPFSLAIFIMMISSLTLVPALLGIFGRVSFWPFVPRTVEMEETRAKKKGKTPKHHKENRFWHKIGEM
SAKHPVRILIITLIILIGCGIFTTQVKYTYDTLSTFPEDMPSREGFTLISDHFGAGMLAPMEVVVNSKESMKSSLENVDG
VASVTGPERSKGYQKYTLILKDNPYSNEAMDVVPKVRAAADKGNDVYIAGQTATQYDDRAVTEHDEKVIIPLVIALIAIL
LLCYLRSITAMLYLVATVLLSFVGALGLGWVIIHYAMGVEAISGLIPLYAFVFIVALGEDYNIFMISSIWKNSKKMPLRK
AITEGVGQTGGVITSAGLILAGTFGVLTTLPIQLLVQFGLITAIGVLLDTFIVRPFLVPSITVLLGKWAFWPGKQHKMTK
>Mature_720_residues
MKDGFLSKIASGVGGKKGRFITLGIWIIAIIILQFFFPKAADYKDDAAKDLPNSEPSVVAQKLIDDKFAGTDGVPALITW
YRSTGLTTEDLVNIQKYSKELTENPVDYQKMAVPYDKMPPVALKQQVSKDGTTFIQTVIMKDSATSDQLTESFKQLESAA
KTTIGENPFAQKVSADDALVARTTGPAGISVDASGLFKDADVSLLIGTVLLVLVFLLVIYRSPILALIPLIAVGFAYLVI
TPILGLLAKEGIITYGSQGLSIMTVLLFGAGTDYCLFLISRFRSHLHTEKNRFQAFKEAFSGTAGAIALSGLTVMTALLL
LLAAEYGSFHNFAVPFSLAIFIMMISSLTLVPALLGIFGRVSFWPFVPRTVEMEETRAKKKGKTPKHHKENRFWHKIGEM
SAKHPVRILIITLIILIGCGIFTTQVKYTYDTLSTFPEDMPSREGFTLISDHFGAGMLAPMEVVVNSKESMKSSLENVDG
VASVTGPERSKGYQKYTLILKDNPYSNEAMDVVPKVRAAADKGNDVYIAGQTATQYDDRAVTEHDEKVIIPLVIALIAIL
LLCYLRSITAMLYLVATVLLSFVGALGLGWVIIHYAMGVEAISGLIPLYAFVFIVALGEDYNIFMISSIWKNSKKMPLRK
AITEGVGQTGGVITSAGLILAGTFGVLTTLPIQLLVQFGLITAIGVLLDTFIVRPFLVPSITVLLGKWAFWPGKQHKMTK

Specific function: Unknown

COG id: COG2409

COG function: function code R; Predicted drug exporters of the RND superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004869
- InterPro:   IPR000731 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 78460; Mature: 78460

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS50156 SSD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDGFLSKIASGVGGKKGRFITLGIWIIAIIILQFFFPKAADYKDDAAKDLPNSEPSVVA
CCCHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHH
QKLIDDKFAGTDGVPALITWYRSTGLTTEDLVNIQKYSKELTENPVDYQKMAVPYDKMPP
HHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCC
VALKQQVSKDGTTFIQTVIMKDSATSDQLTESFKQLESAAKTTIGENPFAQKVSADDALV
HHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCEE
ARTTGPAGISVDASGLFKDADVSLLIGTVLLVLVFLLVIYRSPILALIPLIAVGFAYLVI
EECCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
TPILGLLAKEGIITYGSQGLSIMTVLLFGAGTDYCLFLISRFRSHLHTEKNRFQAFKEAF
HHHHHHHHHCCCCEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGTAGAIALSGLTVMTALLLLLAAEYGSFHNFAVPFSLAIFIMMISSLTLVPALLGIFGR
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSFWPFVPRTVEMEETRAKKKGKTPKHHKENRFWHKIGEMSAKHPVRILIITLIILIGCG
HHHCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
IFTTQVKYTYDTLSTFPEDMPSREGFTLISDHFGAGMLAPMEVVVNSKESMKSSLENVDG
HHHHHHEEHHHHHHHCHHHCCCCCCCEEEHHCCCCCCHHHHHHHHCCHHHHHHHHHHCCC
VASVTGPERSKGYQKYTLILKDNPYSNEAMDVVPKVRAAADKGNDVYIAGQTATQYDDRA
CEECCCCHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCC
VTEHDEKVIIPLVIALIAILLLCYLRSITAMLYLVATVLLSFVGALGLGWVIIHYAMGVE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AISGLIPLYAFVFIVALGEDYNIFMISSIWKNSKKMPLRKAITEGVGQTGGVITSAGLIL
HHHHHHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCHHHHHHHHCCCCCCCHHHHCCHHH
AGTFGVLTTLPIQLLVQFGLITAIGVLLDTFIVRPFLVPSITVLLGKWAFWPGKQHKMTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKDGFLSKIASGVGGKKGRFITLGIWIIAIIILQFFFPKAADYKDDAAKDLPNSEPSVVA
CCCHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHH
QKLIDDKFAGTDGVPALITWYRSTGLTTEDLVNIQKYSKELTENPVDYQKMAVPYDKMPP
HHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCC
VALKQQVSKDGTTFIQTVIMKDSATSDQLTESFKQLESAAKTTIGENPFAQKVSADDALV
HHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCEE
ARTTGPAGISVDASGLFKDADVSLLIGTVLLVLVFLLVIYRSPILALIPLIAVGFAYLVI
EECCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
TPILGLLAKEGIITYGSQGLSIMTVLLFGAGTDYCLFLISRFRSHLHTEKNRFQAFKEAF
HHHHHHHHHCCCCEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGTAGAIALSGLTVMTALLLLLAAEYGSFHNFAVPFSLAIFIMMISSLTLVPALLGIFGR
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSFWPFVPRTVEMEETRAKKKGKTPKHHKENRFWHKIGEMSAKHPVRILIITLIILIGCG
HHHCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
IFTTQVKYTYDTLSTFPEDMPSREGFTLISDHFGAGMLAPMEVVVNSKESMKSSLENVDG
HHHHHHEEHHHHHHHCHHHCCCCCCCEEEHHCCCCCCHHHHHHHHCCHHHHHHHHHHCCC
VASVTGPERSKGYQKYTLILKDNPYSNEAMDVVPKVRAAADKGNDVYIAGQTATQYDDRA
CEECCCCHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCC
VTEHDEKVIIPLVIALIAILLLCYLRSITAMLYLVATVLLSFVGALGLGWVIIHYAMGVE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AISGLIPLYAFVFIVALGEDYNIFMISSIWKNSKKMPLRKAITEGVGQTGGVITSAGLIL
HHHHHHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCHHHHHHHHCCCCCCCHHHHCCHHH
AGTFGVLTTLPIQLLVQFGLITAIGVLLDTFIVRPFLVPSITVLLGKWAFWPGKQHKMTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]