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The map label for this gene is metI [H]

Identifier: 226224966

GI number: 226224966

Start: 2460728

End: 2461402

Strand: Reverse

Name: metI [H]

Synonym: Lm4b_02387

Alternate gene names: 226224966

Gene position: 2461402-2460728 (Counterclockwise)

Preceding gene: 226224967

Following gene: 226224965

Centisome position: 84.51

GC content: 40.15

Gene sequence:

>675_bases
ATGACGAAATTACAAGAATTATTTCCAAATGTTGATTTTCAAATGATGTGGGTCGCAACACAAGAAACATTATACATGAC
GCTTGTTTCATTATTTGCGGTTTTTTTACTCGGGATTGTGTTAGGATTATTACTATTTTTAACTAACAATAAAAAACATG
CCGGAGCGCGCATTCTTTACTGGATTACAGCCATTTTAGTCAATGTGTTCCGCTCGATTCCTTTTATTATTTTAATTGTA
TTACTATTACCGATGACAAAATCGCTTGTCGGAACTGTAATTGGGCCGAAAGCGGCACTTCCAGCTTTGATTATCTCTGC
TGCTCCGTTTTATGGTCGGATGGTAGAAATTGCCTTTCGTGAAGTGGACAAAGGAGTTATTGAAGCAGCCAAATCTATGG
GCGCGAACATGTTTACCATTATTGGTAAAGTGCTCATCCCAGAAGCCTTACCAGCGATTATTTCCGGTATCACAGTGACA
GCAATTTCGCTCGTTGGTTTTACCGCGATGGCTGGTGTCATTGGCGCAGGCGGTCTTGGGAATACTGCCTATCTTGAAGG
GTTCCAACGTGGACAACCTGATGTAACAGTACTTGCGACAATTATTATCTTAATTATCGTCTTTATTTTCCAGTTTATCG
GCGACTTCTTAACAAAACGAACCGACAAACGCTAA

Upstream 100 bases:

>100_bases
ACGGAACGCTTTATGTACAAGTTTTAGGTACAGAAGATGCGATAAATGCGAGTCTAACACAGCTACGTCAACTTAAAGTA
GAAACGGAAGTGTTAGAACG

Downstream 100 bases:

>100_bases
CCAATGTATATGAAGAAATTTATATAAAAAAACGCGGAATCCCCGCAAAAAAGGAGAGAATTTCATGAAAAAGGTTCTTG
GTTTCATTTTCACATTAAGT

Product: ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTKLQELFPNVDFQMMWVATQETLYMTLVSLFAVFLLGIVLGLLLFLTNNKKHAGARILYWITAILVNVFRSIPFIILIV
LLLPMTKSLVGTVIGPKAALPALIISAAPFYGRMVEIAFREVDKGVIEAAKSMGANMFTIIGKVLIPEALPAIISGITVT
AISLVGFTAMAGVIGAGGLGNTAYLEGFQRGQPDVTVLATIIILIIVFIFQFIGDFLTKRTDKR

Sequences:

>Translated_224_residues
MTKLQELFPNVDFQMMWVATQETLYMTLVSLFAVFLLGIVLGLLLFLTNNKKHAGARILYWITAILVNVFRSIPFIILIV
LLLPMTKSLVGTVIGPKAALPALIISAAPFYGRMVEIAFREVDKGVIEAAKSMGANMFTIIGKVLIPEALPAIISGITVT
AISLVGFTAMAGVIGAGGLGNTAYLEGFQRGQPDVTVLATIIILIIVFIFQFIGDFLTKRTDKR
>Mature_223_residues
TKLQELFPNVDFQMMWVATQETLYMTLVSLFAVFLLGIVLGLLLFLTNNKKHAGARILYWITAILVNVFRSIPFIILIVL
LLPMTKSLVGTVIGPKAALPALIISAAPFYGRMVEIAFREVDKGVIEAAKSMGANMFTIIGKVLIPEALPAIISGITVTA
ISLVGFTAMAGVIGAGGLGNTAYLEGFQRGQPDVTVLATIIILIIVFIFQFIGDFLTKRTDKR

Specific function: Part of the ABC transporter complex metNIQ involved in methionine import. Responsible for the translocation of the substrate across the membrane (Probable). It has also been shown to be involved in methionine sulfoxide transport [H]

COG id: COG2011

COG function: function code P; ABC-type metal ion transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786397, Length=213, Percent_Identity=42.7230046948357, Blast_Score=132, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24307; Mature: 24176

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLQELFPNVDFQMMWVATQETLYMTLVSLFAVFLLGIVLGLLLFLTNNKKHAGARILY
CCCHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
WITAILVNVFRSIPFIILIVLLLPMTKSLVGTVIGPKAALPALIISAAPFYGRMVEIAFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHH
EVDKGVIEAAKSMGANMFTIIGKVLIPEALPAIISGITVTAISLVGFTAMAGVIGAGGLG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NTAYLEGFQRGQPDVTVLATIIILIIVFIFQFIGDFLTKRTDKR
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKLQELFPNVDFQMMWVATQETLYMTLVSLFAVFLLGIVLGLLLFLTNNKKHAGARILY
CCHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
WITAILVNVFRSIPFIILIVLLLPMTKSLVGTVIGPKAALPALIISAAPFYGRMVEIAFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHH
EVDKGVIEAAKSMGANMFTIIGKVLIPEALPAIISGITVTAISLVGFTAMAGVIGAGGLG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NTAYLEGFQRGQPDVTVLATIIILIIVFIFQFIGDFLTKRTDKR
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]