Click here to switch to the map view.

The map label for this gene is yhdP [H]

Identifier: 226224950

GI number: 226224950

Start: 2446094

End: 2447404

Strand: Reverse

Name: yhdP [H]

Synonym: Lm4b_02371

Alternate gene names: 226224950

Gene position: 2447404-2446094 (Counterclockwise)

Preceding gene: 226224951

Following gene: 226224946

Centisome position: 84.03

GC content: 40.73

Gene sequence:

>1311_bases
ATGGACATTTTTAATGATTTCTTTGTGATATTTTTAATTGCAGCGACTGCCTTTTTCGTGGCAAGTGAATTTGCCATTGT
CGCAATCCGGAAACCTACTGTCCTGCAACTAGTAGCCTCAGAGGACCCGCGAGCGAAATATGTAAAAAAAGTTACTTCGA
ATATGAATGATTATTTGGCTGCCTGTCAGTTAGGTAATACACTTGCCGCACTTGCTATGGGGTGGGTTGGTGAAGCAACA
ATGCGTGGCTGGTTGGAGCCGTTATTTTTAATGTTACCTGTACCAGAATCCGTTGAAAAGCCGATTTCGATTTTTGTTTC
GTTTATTTTAATTACATTCTTAAATGTGGTACTCGGGGAACTTGCTCCGAAAACATTTACAATTCAAAGCACAGAAAAAG
TAGCTCTGTTTATCGCGCGCCCGCTTGTGTATTGGTATCGCCTGACTTTTCCACTCAATTGGCTTTTAAATAACTCGGCG
AATTTAATCACGCGGATGTTTGGGGTAAAACAAACAGTTGATGCGGACCAAATGACACCGACCGAACTGAAGATTATTTT
TGAAGATAGCTATAGGCAAGGGCTTTTGAATCCACAAGAGTTTCGTTATATGAAAAATATTTTCAAACTCGGGGACGTGC
CAGCGAAAGAAGTAATGATACCGCGAATGTCAATGATTGCGATTGACCAAACGGCGACCGTAAGAGATTTACTGAAATTA
ACTTCTGAACATACATATCATATTTTTCCAGTTACGGAAGATGAAGATAAAGATCATATTATCGGAATGCTACGAGTCAG
TGCGGTTATGGCTGGACTTGGAAAAGATGAAACGATTGTGACGCAATCTATTCAACCATTTATTACACCTGTTTTAGAAG
TGTTTGAAGGCATGATTTTGGAAGAGTTACTTGTGAAAATGCAGCAAGAAAGTGAGCCGTTTGTCGTTCTCACGGATGAA
TACGGCGGGACTTCGGGGATTGTGACGCTAGAAGATGTCATGGAAGTAATTGTTGGTGATATGGAAGAAGCAAAAGGTCC
GAAAGGGATTCGAAAAGTAGCTTTGAATCATTATATTATTGAAGGATCTGAGCCGCTTCTTGAAGTCGAGGAAGCACTGG
GGGTCCCAATTGAAGGGCCGGGTGTTCATACGTTATCGGGATGGATGTTACTCGAACGTTTTGACTTAGAAGCTGGTGAT
GAGATTGAACATGAGGGATACCGCTTTATCGTTCGTTCAATGAATAAAAACTCGATTCGGCAAGTAGAAGTAAAATTAGG
GAAAGAAAAACCAGTAAAATTGGAGGAATAA

Upstream 100 bases:

>100_bases
GATTTGAAAAAACGGGGGAGATCATCGACGGCGAGGCAGTGGCCGACTTGTGGTTCAAACGTTAAAATCGGGTATAGAAT
GGGGATAAGGAGGATGCTAA

Downstream 100 bases:

>100_bases
GCCTCTTGTTTTACTGGTTTTTGTTTAATTAACGATGTCGTCGTGATAACTATGCGCAAGCCGACTTGCAGCGGCCGCAG
CGATAGCGCCAACAATATCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MDIFNDFFVIFLIAATAFFVASEFAIVAIRKPTVLQLVASEDPRAKYVKKVTSNMNDYLAACQLGNTLAALAMGWVGEAT
MRGWLEPLFLMLPVPESVEKPISIFVSFILITFLNVVLGELAPKTFTIQSTEKVALFIARPLVYWYRLTFPLNWLLNNSA
NLITRMFGVKQTVDADQMTPTELKIIFEDSYRQGLLNPQEFRYMKNIFKLGDVPAKEVMIPRMSMIAIDQTATVRDLLKL
TSEHTYHIFPVTEDEDKDHIIGMLRVSAVMAGLGKDETIVTQSIQPFITPVLEVFEGMILEELLVKMQQESEPFVVLTDE
YGGTSGIVTLEDVMEVIVGDMEEAKGPKGIRKVALNHYIIEGSEPLLEVEEALGVPIEGPGVHTLSGWMLLERFDLEAGD
EIEHEGYRFIVRSMNKNSIRQVEVKLGKEKPVKLEE

Sequences:

>Translated_436_residues
MDIFNDFFVIFLIAATAFFVASEFAIVAIRKPTVLQLVASEDPRAKYVKKVTSNMNDYLAACQLGNTLAALAMGWVGEAT
MRGWLEPLFLMLPVPESVEKPISIFVSFILITFLNVVLGELAPKTFTIQSTEKVALFIARPLVYWYRLTFPLNWLLNNSA
NLITRMFGVKQTVDADQMTPTELKIIFEDSYRQGLLNPQEFRYMKNIFKLGDVPAKEVMIPRMSMIAIDQTATVRDLLKL
TSEHTYHIFPVTEDEDKDHIIGMLRVSAVMAGLGKDETIVTQSIQPFITPVLEVFEGMILEELLVKMQQESEPFVVLTDE
YGGTSGIVTLEDVMEVIVGDMEEAKGPKGIRKVALNHYIIEGSEPLLEVEEALGVPIEGPGVHTLSGWMLLERFDLEAGD
EIEHEGYRFIVRSMNKNSIRQVEVKLGKEKPVKLEE
>Mature_436_residues
MDIFNDFFVIFLIAATAFFVASEFAIVAIRKPTVLQLVASEDPRAKYVKKVTSNMNDYLAACQLGNTLAALAMGWVGEAT
MRGWLEPLFLMLPVPESVEKPISIFVSFILITFLNVVLGELAPKTFTIQSTEKVALFIARPLVYWYRLTFPLNWLLNNSA
NLITRMFGVKQTVDADQMTPTELKIIFEDSYRQGLLNPQEFRYMKNIFKLGDVPAKEVMIPRMSMIAIDQTATVRDLLKL
TSEHTYHIFPVTEDEDKDHIIGMLRVSAVMAGLGKDETIVTQSIQPFITPVLEVFEGMILEELLVKMQQESEPFVVLTDE
YGGTSGIVTLEDVMEVIVGDMEEAKGPKGIRKVALNHYIIEGSEPLLEVEEALGVPIEGPGVHTLSGWMLLERFDLEAGD
EIEHEGYRFIVRSMNKNSIRQVEVKLGKEKPVKLEE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=394, Percent_Identity=38.8324873096447, Blast_Score=285, Evalue=5e-77,
Organism=Escherichia coli, GI1790664, Length=432, Percent_Identity=28.9351851851852, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI145693175, Length=418, Percent_Identity=25.1196172248804, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1786879, Length=260, Percent_Identity=26.9230769230769, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082033, Length=266, Percent_Identity=24.0601503759398, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49104; Mature: 49104

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIFNDFFVIFLIAATAFFVASEFAIVAIRKPTVLQLVASEDPRAKYVKKVTSNMNDYLA
CCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCEEEEECCCCCHHHHHHHHHCCHHHHHH
ACQLGNTLAALAMGWVGEATMRGWLEPLFLMLPVPESVEKPISIFVSFILITFLNVVLGE
HHHHCHHHHHHHHHHCCHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAPKTFTIQSTEKVALFIARPLVYWYRLTFPLNWLLNNSANLITRMFGVKQTVDADQMTP
CCCCEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHCCHHCCCCCCCCC
TELKIIFEDSYRQGLLNPQEFRYMKNIFKLGDVPAKEVMIPRMSMIAIDQTATVRDLLKL
CCEEEEEECCHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCHHEEEECCHHHHHHHHHH
TSEHTYHIFPVTEDEDKDHIIGMLRVSAVMAGLGKDETIVTQSIQPFITPVLEVFEGMIL
HCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
EELLVKMQQESEPFVVLTDEYGGTSGIVTLEDVMEVIVGDMEEAKGPKGIRKVALNHYII
HHHHHHHHCCCCCEEEEEECCCCCCCCEEHHHHHHHHHCCHHHCCCCHHHHHHHHHHEEE
EGSEPLLEVEEALGVPIEGPGVHTLSGWMLLERFDLEAGDEIEHEGYRFIVRSMNKNSIR
CCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCE
QVEVKLGKEKPVKLEE
EEEEECCCCCCCCCCC
>Mature Secondary Structure
MDIFNDFFVIFLIAATAFFVASEFAIVAIRKPTVLQLVASEDPRAKYVKKVTSNMNDYLA
CCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCEEEEECCCCCHHHHHHHHHCCHHHHHH
ACQLGNTLAALAMGWVGEATMRGWLEPLFLMLPVPESVEKPISIFVSFILITFLNVVLGE
HHHHCHHHHHHHHHHCCHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAPKTFTIQSTEKVALFIARPLVYWYRLTFPLNWLLNNSANLITRMFGVKQTVDADQMTP
CCCCEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHCCHHCCCCCCCCC
TELKIIFEDSYRQGLLNPQEFRYMKNIFKLGDVPAKEVMIPRMSMIAIDQTATVRDLLKL
CCEEEEEECCHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCHHEEEECCHHHHHHHHHH
TSEHTYHIFPVTEDEDKDHIIGMLRVSAVMAGLGKDETIVTQSIQPFITPVLEVFEGMIL
HCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
EELLVKMQQESEPFVVLTDEYGGTSGIVTLEDVMEVIVGDMEEAKGPKGIRKVALNHYII
HHHHHHHHCCCCCEEEEEECCCCCCCCEEHHHHHHHHHCCHHHCCCCHHHHHHHHHHEEE
EGSEPLLEVEEALGVPIEGPGVHTLSGWMLLERFDLEAGDEIEHEGYRFIVRSMNKNSIR
CCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCE
QVEVKLGKEKPVKLEE
EEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]