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The map label for this gene is rsbRD [H]

Identifier: 226224445

GI number: 226224445

Start: 1904938

End: 1905762

Strand: Direct

Name: rsbRD [H]

Synonym: Lm4b_01858

Alternate gene names: 226224445

Gene position: 1904938-1905762 (Clockwise)

Preceding gene: 226224444

Following gene: 226224449

Centisome position: 65.4

GC content: 34.3

Gene sequence:

>825_bases
ATGGGCATAATGAATAGCTTATTACAACAGAAAGAAATGGTCGTGAAAGATTGGCTAACGTATTATGTATCTGTAGATGA
TCCATATATCTTCACATTAAAAAATGATCATCGTTTAATGGATGAAACGGGCTTTGTTTTAGAAAATTTGTTTATTGGAA
TGACTGAAGATTTAGGAAAAATGAATGCTTTCGCGCGTGAGCTTGGAAAAGCACAGTTTATTACTTCACTCGGAATTTCT
CGTATTTTATTCCATATTCGCTTACTGGAAGAGTTTTTGCTCGATTATGCATCAGAAATCAAAACAAAATCTGCTAATTA
TCGTGAATTATATTTATTTAGCATCAAGCTTCATCAGGTATTTAGTAGTTTCACGCAAAACTTAATCGAAGGCTATACCC
GTGCAAATGAACAAAAGATTATACAAAAAGAAAACCAAATTATTAAAGAATCAACCAAACTAATTTGGATTGCCGAAAAT
GTTTTTCTGTTACCTTTAATTGGAAGAATTACCGATGAGCGAGCAAAACAACTTACTGAAACAGCGCTTGTTGAAGTTTG
TGAGCAACCAGTGAACTATTTAATTATCGACTTATCTGGCGTGCAGTTAGAGTCTCCTAACATCGGCAAGTACATTGAGT
ATTTCTTCTCGTCGCTTAAATTAGTAGGTGTAACTCCGATTATTACAGGTATGCAACCGCAAACTGCCAAAGTGATGGTT
CAAGTTAATTTAACTGAACAACATGGTATTAAAACATTTGCAACCTTACGCCAAGCAACAAAAACACTTATGAAAGAAAA
AGAAGCAAGAAACGCCCGTAAATAG

Upstream 100 bases:

>100_bases
CAACTTGAAATAGTCTACTTTTACCAGAAATTAGTCCAATTTAACTGCTCTATGTGCTATGCTGAAATAGCTAAAAACAT
GGACTTAAGAGGTGAATACA

Downstream 100 bases:

>100_bases
GTGTTCTTGCTTCTTTTTTAATATTCTTCTTGACGTAATGATTTTAAAGCTTTTTCAAAGGAACTAGGAAGTGGCGCTTC
AAACATCATTCGTTCTTTCG

Product: hypothetical protein

Products: NA

Alternate protein names: Stressosome protein rsbRD [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MGIMNSLLQQKEMVVKDWLTYYVSVDDPYIFTLKNDHRLMDETGFVLENLFIGMTEDLGKMNAFARELGKAQFITSLGIS
RILFHIRLLEEFLLDYASEIKTKSANYRELYLFSIKLHQVFSSFTQNLIEGYTRANEQKIIQKENQIIKESTKLIWIAEN
VFLLPLIGRITDERAKQLTETALVEVCEQPVNYLIIDLSGVQLESPNIGKYIEYFFSSLKLVGVTPIITGMQPQTAKVMV
QVNLTEQHGIKTFATLRQATKTLMKEKEARNARK

Sequences:

>Translated_274_residues
MGIMNSLLQQKEMVVKDWLTYYVSVDDPYIFTLKNDHRLMDETGFVLENLFIGMTEDLGKMNAFARELGKAQFITSLGIS
RILFHIRLLEEFLLDYASEIKTKSANYRELYLFSIKLHQVFSSFTQNLIEGYTRANEQKIIQKENQIIKESTKLIWIAEN
VFLLPLIGRITDERAKQLTETALVEVCEQPVNYLIIDLSGVQLESPNIGKYIEYFFSSLKLVGVTPIITGMQPQTAKVMV
QVNLTEQHGIKTFATLRQATKTLMKEKEARNARK
>Mature_273_residues
GIMNSLLQQKEMVVKDWLTYYVSVDDPYIFTLKNDHRLMDETGFVLENLFIGMTEDLGKMNAFARELGKAQFITSLGISR
ILFHIRLLEEFLLDYASEIKTKSANYRELYLFSIKLHQVFSSFTQNLIEGYTRANEQKIIQKENQIIKESTKLIWIAENV
FLLPLIGRITDERAKQLTETALVEVCEQPVNYLIIDLSGVQLESPNIGKYIEYFFSSLKLVGVTPIITGMQPQTAKVMVQ
VNLTEQHGIKTFATLRQATKTLMKEKEARNARK

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 31574; Mature: 31443

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIMNSLLQQKEMVVKDWLTYYVSVDDPYIFTLKNDHRLMDETGFVLENLFIGMTEDLGK
CCHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHH
MNAFARELGKAQFITSLGISRILFHIRLLEEFLLDYASEIKTKSANYRELYLFSIKLHQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHH
FSSFTQNLIEGYTRANEQKIIQKENQIIKESTKLIWIAENVFLLPLIGRITDERAKQLTE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
TALVEVCEQPVNYLIIDLSGVQLESPNIGKYIEYFFSSLKLVGVTPIITGMQPQTAKVMV
HHHHHHHHCCCCEEEEEECCCEECCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEE
QVNLTEQHGIKTFATLRQATKTLMKEKEARNARK
EEECCHHHCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GIMNSLLQQKEMVVKDWLTYYVSVDDPYIFTLKNDHRLMDETGFVLENLFIGMTEDLGK
CHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHH
MNAFARELGKAQFITSLGISRILFHIRLLEEFLLDYASEIKTKSANYRELYLFSIKLHQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHH
FSSFTQNLIEGYTRANEQKIIQKENQIIKESTKLIWIAENVFLLPLIGRITDERAKQLTE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
TALVEVCEQPVNYLIIDLSGVQLESPNIGKYIEYFFSSLKLVGVTPIITGMQPQTAKVMV
HHHHHHHHCCCCEEEEEECCCEECCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEE
QVNLTEQHGIKTFATLRQATKTLMKEKEARNARK
EEECCHHHCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 11157946 [H]