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The map label for this gene is yqjV [H]

Identifier: 226224315

GI number: 226224315

Start: 1759922

End: 1761181

Strand: Direct

Name: yqjV [H]

Synonym: Lm4b_01726

Alternate gene names: 226224315

Gene position: 1759922-1761181 (Clockwise)

Preceding gene: 226224314

Following gene: 226224316

Centisome position: 60.42

GC content: 38.73

Gene sequence:

>1260_bases
ATGAAATTTAGTACATGGGACATCAATTTAAAAGTAAGGCTTTTTGGGGAAGCACTACTCGATATTTCTTTTTGGATGGT
CTTCCCCTTTCTAACGATTTACTTTTCGGAAAGTATTGGGCGCGAGCTGACGAGCCTTTTGCTGATTATTTCGCAAGTTT
TGGCGGTTTTCACAGCTTTGCTTGGCGGTTATTTTGCGGATAACTTTGGTCGTAAACGGATGATGAGTATTTCTGTCATT
GGAGAAGGTTTTGGTTTTCTTGTTTTTGCAATAGGTGCACTTCATGTTGTGGATTCTCCTTACTTGAGTTTTGCTGGTTT
CGCGATTGCGAGTGTTTTTATGGCGTTTTATCAGCCAGCAAGTCAAGCGATGATTGCCGATGTGGTTCCTCCTGAGCATC
GGACGCATATTTATTCGGTGTTCTATATGATGATTAATATTGCGGTCGTTATTGGCCCCATTCTTGGTTCGGTTTTATTT
TATAATTTCACGACAGAAACACTACTTGCAATTGTTTGTGCGGATTTATTATTACTATTTTTATTGCAAAAATTTGGTCA
CGAAACAGCCCCTCTTTTAGTTAATCCTGATTTACAAAAAGAAGCGGTTCGAAAAAGTATTGGTGCTGTTTTAATGGAAC
AGCTAAAAAACTATAAGATTATTTTTAAAGACAAGATTTTCTTTCTTTATATTGTTGCCGGGATTATTGTTTCTCAGTCG
TTTATGCAACTGGATTTACTTTTCCCGCTCTATATTAAAGAAGTTATCGGCGCCTCTAACTTGTTCGCGTTTCATTTTAC
AGGTGAGCAATTGTTCGGGGTTATTGTTTCTATTAATGGCTTCTTTGTTGCAGCGCTTACTGTCGTTGTCACTCGCTGGA
TGAGCCATTTTAGAGAAAAATTTGTCTTTATGAATTCTTCTTTTCTCTATGCGATTGCGATTTTCTTATTTGGTATTTCG
ACAGGACCGTGGGGAGCGATTTGTGCCATTATTCTCTTTAGCTTCGCGGAACTGATGACTGTTGGCTTGCAACAAACCTT
TGTTTCACAGTTAGCTCCAGAGGATAAACGGGCGATGTACTTCTCTGCTGCTGGACTTCGTTATACGCTGGGTAAAGTCA
TTGCTCCACTTGCGATTACACTTTCGACTTTAATTGGCTATACTGGGACATTTACTATTATTGGTATTTTAGCGCTCATT
AGCGGGCTCATTTATTACTATATGTATTCAGAATTTGAAAAACAGCGGCAAGTTTCCTAA

Upstream 100 bases:

>100_bases
TTTTTTAAAACTTATGCCTTTTGCGTAAAACCCTTGTAGCTTTTGGCTTTCAAGGGTTTTCGTTTGTTTATTTTTTACAA
AAGAGAGCGAGGTGCATTGG

Downstream 100 bases:

>100_bases
TAAAAAACGGCTATCTACTCTGGATAGTCGTTTTTGTTTGATTACTTTTTTTACGATTTATTTACGAAACACCGAAAACA
CCTGTCATATCGCCATTTTA

Product: multidrug resistance protein, integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MKFSTWDINLKVRLFGEALLDISFWMVFPFLTIYFSESIGRELTSLLLIISQVLAVFTALLGGYFADNFGRKRMMSISVI
GEGFGFLVFAIGALHVVDSPYLSFAGFAIASVFMAFYQPASQAMIADVVPPEHRTHIYSVFYMMINIAVVIGPILGSVLF
YNFTTETLLAIVCADLLLLFLLQKFGHETAPLLVNPDLQKEAVRKSIGAVLMEQLKNYKIIFKDKIFFLYIVAGIIVSQS
FMQLDLLFPLYIKEVIGASNLFAFHFTGEQLFGVIVSINGFFVAALTVVVTRWMSHFREKFVFMNSSFLYAIAIFLFGIS
TGPWGAICAIILFSFAELMTVGLQQTFVSQLAPEDKRAMYFSAAGLRYTLGKVIAPLAITLSTLIGYTGTFTIIGILALI
SGLIYYYMYSEFEKQRQVS

Sequences:

>Translated_419_residues
MKFSTWDINLKVRLFGEALLDISFWMVFPFLTIYFSESIGRELTSLLLIISQVLAVFTALLGGYFADNFGRKRMMSISVI
GEGFGFLVFAIGALHVVDSPYLSFAGFAIASVFMAFYQPASQAMIADVVPPEHRTHIYSVFYMMINIAVVIGPILGSVLF
YNFTTETLLAIVCADLLLLFLLQKFGHETAPLLVNPDLQKEAVRKSIGAVLMEQLKNYKIIFKDKIFFLYIVAGIIVSQS
FMQLDLLFPLYIKEVIGASNLFAFHFTGEQLFGVIVSINGFFVAALTVVVTRWMSHFREKFVFMNSSFLYAIAIFLFGIS
TGPWGAICAIILFSFAELMTVGLQQTFVSQLAPEDKRAMYFSAAGLRYTLGKVIAPLAITLSTLIGYTGTFTIIGILALI
SGLIYYYMYSEFEKQRQVS
>Mature_419_residues
MKFSTWDINLKVRLFGEALLDISFWMVFPFLTIYFSESIGRELTSLLLIISQVLAVFTALLGGYFADNFGRKRMMSISVI
GEGFGFLVFAIGALHVVDSPYLSFAGFAIASVFMAFYQPASQAMIADVVPPEHRTHIYSVFYMMINIAVVIGPILGSVLF
YNFTTETLLAIVCADLLLLFLLQKFGHETAPLLVNPDLQKEAVRKSIGAVLMEQLKNYKIIFKDKIFFLYIVAGIIVSQS
FMQLDLLFPLYIKEVIGASNLFAFHFTGEQLFGVIVSINGFFVAALTVVVTRWMSHFREKFVFMNSSFLYAIAIFLFGIS
TGPWGAICAIILFSFAELMTVGLQQTFVSQLAPEDKRAMYFSAAGLRYTLGKVIAPLAITLSTLIGYTGTFTIIGILALI
SGLIYYYMYSEFEKQRQVS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI1787815, Length=359, Percent_Identity=25.0696378830084, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081828, Length=359, Percent_Identity=22.8412256267409, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001958 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46874; Mature: 46874

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSTWDINLKVRLFGEALLDISFWMVFPFLTIYFSESIGRELTSLLLIISQVLAVFTAL
CCCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGGYFADNFGRKRMMSISVIGEGFGFLVFAIGALHVVDSPYLSFAGFAIASVFMAFYQPA
HHHHHHHCCCHHHEEEHEEHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCH
SQAMIADVVPPEHRTHIYSVFYMMINIAVVIGPILGSVLFYNFTTETLLAIVCADLLLLF
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQKFGHETAPLLVNPDLQKEAVRKSIGAVLMEQLKNYKIIFKDKIFFLYIVAGIIVSQS
HHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHH
FMQLDLLFPLYIKEVIGASNLFAFHFTGEQLFGVIVSINGFFVAALTVVVTRWMSHFREK
HHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVFMNSSFLYAIAIFLFGISTGPWGAICAIILFSFAELMTVGLQQTFVSQLAPEDKRAMY
HHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEE
FSAAGLRYTLGKVIAPLAITLSTLIGYTGTFTIIGILALISGLIYYYMYSEFEKQRQVS
EECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFSTWDINLKVRLFGEALLDISFWMVFPFLTIYFSESIGRELTSLLLIISQVLAVFTAL
CCCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGGYFADNFGRKRMMSISVIGEGFGFLVFAIGALHVVDSPYLSFAGFAIASVFMAFYQPA
HHHHHHHCCCHHHEEEHEEHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCH
SQAMIADVVPPEHRTHIYSVFYMMINIAVVIGPILGSVLFYNFTTETLLAIVCADLLLLF
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQKFGHETAPLLVNPDLQKEAVRKSIGAVLMEQLKNYKIIFKDKIFFLYIVAGIIVSQS
HHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHH
FMQLDLLFPLYIKEVIGASNLFAFHFTGEQLFGVIVSINGFFVAALTVVVTRWMSHFREK
HHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVFMNSSFLYAIAIFLFGISTGPWGAICAIILFSFAELMTVGLQQTFVSQLAPEDKRAMY
HHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEE
FSAAGLRYTLGKVIAPLAITLSTLIGYTGTFTIIGILALISGLIYYYMYSEFEKQRQVS
EECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]