| Definition | Listeria monocytogenes Clip81459, complete genome. |
|---|---|
| Accession | NC_012488 |
| Length | 2,912,690 |
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The map label for this gene is fabL [H]
Identifier: 226224291
GI number: 226224291
Start: 1739503
End: 1740249
Strand: Reverse
Name: fabL [H]
Synonym: Lm4b_01702b
Alternate gene names: 226224291
Gene position: 1740249-1739503 (Counterclockwise)
Preceding gene: 226224292
Following gene: 226224290
Centisome position: 59.75
GC content: 38.82
Gene sequence:
>747_bases ATGAATAGAGTGGCATTAGTAACAGGAAGTAGTAGAGGACTTGGAAGAGAAATAGCCATCGCACTTGCAAATGAAGGCTA TGATATCGCTGTTAATTTTTCCAGAAATCGCAAAAAAGCAGAAGAAGTACAACAAGAAATTGAACAATTAGGAAGAAAAT GCGTTATTTTTAAAGCAAATGTTGGTGACGTGGAAAAAATTAGAGACTTATTTAAAGCTGTAGATGAGGAATTCGGCCGA TTAGATATTTTTATTAACAATGCAGCAAGTGGTGTCCTTCGACCATTGATGGAGTTAGAGGAATCACATTGGGATTGGAC AATGAATATTAACGCAAAAGCGCTGTTGTTTGCAGGTCAAGAAGCAGCTAAATTAATGCAACGCCATCAAAGCGGGAAAA TCATCAGCTTAAGCTCGATTGGCTCGATTCGTTATTTAGAAAATTACACAACAGTTGGCGTTTCAAAAGCGGCGGTAGAA TCACTTACTCGGTATTTAGCAGTTGAACTTGCACCTTTTGGCATTGCAGTTAATGCTGTTTCTGGCGGCTTAATTGAAAC AGACGCACTAAATCACTTTCCCAATCGTGAAGAATTGTTAAAAGATGCTATAAGTAAAACACCAGCGGGTCGAATGATTG AGCCCAATGACTTAGTAAATGCCGTATTATTCCTTGCGAGCGAAAAAGCAGATATGATTCGCGGGCAAACTATTTTAGTA GATGGCGGCAGAACACTTTTAGTATAG
Upstream 100 bases:
>100_bases TTGGTATTTTGCAACAGAAGAAGAAATGAAGCGACTTGCTTTTCCAGTACCATATCAAAAAATGTGGCAAGCGTGGAAAG ATTTTAAGGGGGAATAACAA
Downstream 100 bases:
>100_bases TAAAACAAAATAGGTAAAAATTAGCTATTTTATGTAAAAAAAGTTCTTTTTTGAGGAAAATATTCCGTTTCAGCACGATA TTGTTTTTTTGCAGTCTTGC
Product: enoyl-(acyl carrier protein) reductase
Products: NA
Alternate protein names: Enoyl-acyl carrier protein reductase III; NADPH-dependent enoyl-ACP reductase [H]
Number of amino acids: Translated: 248; Mature: 248
Protein sequence:
>248_residues MNRVALVTGSSRGLGREIAIALANEGYDIAVNFSRNRKKAEEVQQEIEQLGRKCVIFKANVGDVEKIRDLFKAVDEEFGR LDIFINNAASGVLRPLMELEESHWDWTMNINAKALLFAGQEAAKLMQRHQSGKIISLSSIGSIRYLENYTTVGVSKAAVE SLTRYLAVELAPFGIAVNAVSGGLIETDALNHFPNREELLKDAISKTPAGRMIEPNDLVNAVLFLASEKADMIRGQTILV DGGRTLLV
Sequences:
>Translated_248_residues MNRVALVTGSSRGLGREIAIALANEGYDIAVNFSRNRKKAEEVQQEIEQLGRKCVIFKANVGDVEKIRDLFKAVDEEFGR LDIFINNAASGVLRPLMELEESHWDWTMNINAKALLFAGQEAAKLMQRHQSGKIISLSSIGSIRYLENYTTVGVSKAAVE SLTRYLAVELAPFGIAVNAVSGGLIETDALNHFPNREELLKDAISKTPAGRMIEPNDLVNAVLFLASEKADMIRGQTILV DGGRTLLV >Mature_248_residues MNRVALVTGSSRGLGREIAIALANEGYDIAVNFSRNRKKAEEVQQEIEQLGRKCVIFKANVGDVEKIRDLFKAVDEEFGR LDIFINNAASGVLRPLMELEESHWDWTMNINAKALLFAGQEAAKLMQRHQSGKIISLSSIGSIRYLENYTTVGVSKAAVE SLTRYLAVELAPFGIAVNAVSGGLIETDALNHFPNREELLKDAISKTPAGRMIEPNDLVNAVLFLASEKADMIRGQTILV DGGRTLLV
Specific function: Unknown
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=32.9268292682927, Blast_Score=115, Evalue=4e-26, Organism=Homo sapiens, GI7705925, Length=242, Percent_Identity=30.9917355371901, Blast_Score=112, Evalue=4e-25, Organism=Homo sapiens, GI209862901, Length=215, Percent_Identity=33.953488372093, Blast_Score=111, Evalue=6e-25, Organism=Homo sapiens, GI19923983, Length=215, Percent_Identity=33.953488372093, Blast_Score=111, Evalue=6e-25, Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=32.1428571428571, Blast_Score=107, Evalue=7e-24, Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=26.4, Blast_Score=99, Evalue=2e-21, Organism=Homo sapiens, GI5031737, Length=250, Percent_Identity=31.2, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=31.7460317460317, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=28.4, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI40254992, Length=250, Percent_Identity=28.8, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI66933014, Length=183, Percent_Identity=28.4153005464481, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=29.045643153527, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI31542939, Length=205, Percent_Identity=27.8048780487805, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=31.413612565445, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI126723191, Length=180, Percent_Identity=31.1111111111111, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI4503301, Length=211, Percent_Identity=27.4881516587678, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI59889578, Length=216, Percent_Identity=28.7037037037037, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI224922801, Length=171, Percent_Identity=28.0701754385965, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI4504505, Length=239, Percent_Identity=25.9414225941423, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI4503817, Length=178, Percent_Identity=26.9662921348315, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI31543615, Length=234, Percent_Identity=26.9230769230769, Blast_Score=64, Evalue=8e-11, Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=35.8870967741936, Blast_Score=135, Evalue=4e-33, Organism=Escherichia coli, GI1790717, Length=243, Percent_Identity=29.6296296296296, Blast_Score=122, Evalue=3e-29, Organism=Escherichia coli, GI1788459, Length=247, Percent_Identity=27.9352226720648, Blast_Score=115, Evalue=2e-27, Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=32.6612903225806, Blast_Score=115, Evalue=2e-27, Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=29.9595141700405, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI87082160, Length=242, Percent_Identity=29.3388429752066, Blast_Score=109, Evalue=1e-25, Organism=Escherichia coli, GI1787905, Length=241, Percent_Identity=30.2904564315353, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=31.5789473684211, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=29.3650793650794, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1789057, Length=266, Percent_Identity=29.3233082706767, Blast_Score=91, Evalue=8e-20, Organism=Escherichia coli, GI1787545, Length=249, Percent_Identity=25.3012048192771, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=27.2, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI2367365, Length=243, Percent_Identity=27.1604938271605, Blast_Score=77, Evalue=7e-16, Organism=Escherichia coli, GI1787526, Length=247, Percent_Identity=25.1012145748988, Blast_Score=61, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=34.0740740740741, Blast_Score=124, Evalue=7e-29, Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=33.9622641509434, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=32.4427480916031, Blast_Score=114, Evalue=6e-26, Organism=Caenorhabditis elegans, GI115534694, Length=239, Percent_Identity=32.2175732217573, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=34.2205323193916, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=32.2834645669291, Blast_Score=110, Evalue=5e-25, Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=32.8301886792453, Blast_Score=110, Evalue=5e-25, Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=31.9548872180451, Blast_Score=107, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=29.3893129770992, Blast_Score=106, Evalue=9e-24, Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=31.6981132075472, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=29.8039215686275, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=29.7397769516729, Blast_Score=101, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=29.718875502008, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=30.5970149253731, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17560150, Length=267, Percent_Identity=28.0898876404494, Blast_Score=97, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=30.3703703703704, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI72000259, Length=269, Percent_Identity=28.6245353159851, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=28, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17536651, Length=249, Percent_Identity=28.5140562248996, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=30.7086614173228, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=28.030303030303, Blast_Score=89, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17555612, Length=206, Percent_Identity=31.0679611650485, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17563726, Length=256, Percent_Identity=27.34375, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=27.3764258555133, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17538486, Length=272, Percent_Identity=27.5735294117647, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI71997099, Length=208, Percent_Identity=27.4038461538462, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=27.3092369477912, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=25.0950570342205, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17561272, Length=237, Percent_Identity=27.4261603375527, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=27.3469387755102, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17568967, Length=188, Percent_Identity=30.8510638297872, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17538182, Length=251, Percent_Identity=26.6932270916335, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17508651, Length=247, Percent_Identity=28.7449392712551, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71982365, Length=188, Percent_Identity=25.531914893617, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI86565303, Length=211, Percent_Identity=25.5924170616114, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17564282, Length=135, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=246, Percent_Identity=25.609756097561, Blast_Score=80, Evalue=3e-16, Organism=Saccharomyces cerevisiae, GI6323882, Length=244, Percent_Identity=25.8196721311475, Blast_Score=64, Evalue=2e-11, Organism=Drosophila melanogaster, GI21355319, Length=244, Percent_Identity=32.3770491803279, Blast_Score=122, Evalue=2e-28, Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=31.6, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=31.640625, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=29.8387096774194, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=28.1632653061224, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=29.296875, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=30, Blast_Score=91, Evalue=6e-19, Organism=Drosophila melanogaster, GI24644337, Length=181, Percent_Identity=30.3867403314917, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI116007236, Length=240, Percent_Identity=27.0833333333333, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24641232, Length=238, Percent_Identity=26.890756302521, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI21357673, Length=186, Percent_Identity=25.2688172043011, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24649181, Length=168, Percent_Identity=27.9761904761905, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI17737361, Length=253, Percent_Identity=26.4822134387352, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI21355631, Length=170, Percent_Identity=27.0588235294118, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI18859837, Length=232, Percent_Identity=29.3103448275862, Blast_Score=65, Evalue=6e-11, Organism=Drosophila melanogaster, GI116007238, Length=211, Percent_Identity=26.5402843601896, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.10 [H]
Molecular weight: Translated: 27215; Mature: 27215
Theoretical pI: Translated: 5.82; Mature: 5.82
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNRVALVTGSSRGLGREIAIALANEGYDIAVNFSRNRKKAEEVQQEIEQLGRKCVIFKAN CCEEEEEECCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEECC VGDVEKIRDLFKAVDEEFGRLDIFINNAASGVLRPLMELEESHWDWTMNINAKALLFAGQ CCCHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCEEEEEECH EAAKLMQRHQSGKIISLSSIGSIRYLENYTTVGVSKAAVESLTRYLAVELAPFGIAVNAV HHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECC SGGLIETDALNHFPNREELLKDAISKTPAGRMIEPNDLVNAVLFLASEKADMIRGQTILV CCCEEECHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHCCCEEEE DGGRTLLV ECCCEECC >Mature Secondary Structure MNRVALVTGSSRGLGREIAIALANEGYDIAVNFSRNRKKAEEVQQEIEQLGRKCVIFKAN CCEEEEEECCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEECC VGDVEKIRDLFKAVDEEFGRLDIFINNAASGVLRPLMELEESHWDWTMNINAKALLFAGQ CCCHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCEEEEEECH EAAKLMQRHQSGKIISLSSIGSIRYLENYTTVGVSKAAVESLTRYLAVELAPFGIAVNAV HHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECC SGGLIETDALNHFPNREELLKDAISKTPAGRMIEPNDLVNAVLFLASEKADMIRGQTILV CCCEEECHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHCCCEEEE DGGRTLLV ECCCEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8946165; 9202460; 9384377 [H]