Click here to switch to the map view.

The map label for this gene is accD

Identifier: 226224174

GI number: 226224174

Start: 1596094

End: 1596978

Strand: Reverse

Name: accD

Synonym: Lm4b_01584

Alternate gene names: 226224174

Gene position: 1596978-1596094 (Counterclockwise)

Preceding gene: 226224175

Following gene: 226224173

Centisome position: 54.83

GC content: 39.44

Gene sequence:

>885_bases
TTGCTAGGAGACTTGTTTACAAAACCAAAAAAGAGAAAATATGCCACAATTCCTTCTGATGGAACGAAAGCAGATGTTCC
AGAAGGTATTATGACAAAATGTCCGGAATGTAAAAAAATAATGTATACCAAAGAATTGCAAAAAAATCTTATGGTATGTA
ATTATTGTGGTTTTCATCATCCAATTGGGGCAAAAGCACGAATCGATATGCTAGTTGATGAAGGCTCTTTTGAAGAAATT
GATGCTAGTTTAACGACAGCAAATCCACTTGGTTTTGAAGATTATATGGATCGTATTGAGAAAGATAAGCAAAAATCTGG
TTTAAATGAAGCCATTGTTACTGGTCATGCTACAATTGATGGTAATCCGCTTGTTATTGCAGTGATGGATTCTCGTTTTA
GAATGGCAAGTATGGGCTCTGTTGTCGGTGAAAAAATCTTTCGTGCCGTGGAAGATGCCGATAAAACAAATAAACCGTTT
GTTATTTTCACTGCTTCAGGTGGCGCGCGTATGCAAGAGGGGATGCTTTCGCTTATGCAAATGGCGAAAACCTCTGCTGC
ATTTAAACGATTTAGCAATCACGGGGGACTGATTATTACGGTAATGACGCACCCAACTACTGGTGGGGTTTCTGCTAGTT
TTGCATCCCTTGGAGACTATAACTTTGCAGAACCAGGCGCACTTATTGGCTTTGCTGGACGCCGGGTAATAGAACAAACC
GTTCGTGAAGAATTACCAGAAGACTTCCAAACGTCGGAGTTTTTATTAAAGCATGGACAACTAGATGACTGTATTTCACG
CCTTGATCTGCAAAATAAATTAAGTTTTATTTTAAGCATTCACGTGAAAACACCTGAAGTAGGAGGTGAAGCGGATGGCG
AATGA

Upstream 100 bases:

>100_bases
GCGGTTGATTTATGTTTCATGTCTTTATTCATTTTTTATTTTTACAACATTAAAAATCGTTAATAACCACAATAGAAAGC
GTAAATGGGGAGGGTTATCC

Downstream 100 bases:

>100_bases
GATGGAATTTGAGAAACCGATTTTAGAATTAAAAAGTAAGATTGCTGACTTAAAAGAGTACAATGAAACTTCTGATGTGG
ATTTGACCAATGAAATTGAA

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MLGDLFTKPKKRKYATIPSDGTKADVPEGIMTKCPECKKIMYTKELQKNLMVCNYCGFHHPIGAKARIDMLVDEGSFEEI
DASLTTANPLGFEDYMDRIEKDKQKSGLNEAIVTGHATIDGNPLVIAVMDSRFRMASMGSVVGEKIFRAVEDADKTNKPF
VIFTASGGARMQEGMLSLMQMAKTSAAFKRFSNHGGLIITVMTHPTTGGVSASFASLGDYNFAEPGALIGFAGRRVIEQT
VREELPEDFQTSEFLLKHGQLDDCISRLDLQNKLSFILSIHVKTPEVGGEADGE

Sequences:

>Translated_294_residues
MLGDLFTKPKKRKYATIPSDGTKADVPEGIMTKCPECKKIMYTKELQKNLMVCNYCGFHHPIGAKARIDMLVDEGSFEEI
DASLTTANPLGFEDYMDRIEKDKQKSGLNEAIVTGHATIDGNPLVIAVMDSRFRMASMGSVVGEKIFRAVEDADKTNKPF
VIFTASGGARMQEGMLSLMQMAKTSAAFKRFSNHGGLIITVMTHPTTGGVSASFASLGDYNFAEPGALIGFAGRRVIEQT
VREELPEDFQTSEFLLKHGQLDDCISRLDLQNKLSFILSIHVKTPEVGGEADGE
>Mature_294_residues
MLGDLFTKPKKRKYATIPSDGTKADVPEGIMTKCPECKKIMYTKELQKNLMVCNYCGFHHPIGAKARIDMLVDEGSFEEI
DASLTTANPLGFEDYMDRIEKDKQKSGLNEAIVTGHATIDGNPLVIAVMDSRFRMASMGSVVGEKIFRAVEDADKTNKPF
VIFTASGGARMQEGMLSLMQMAKTSAAFKRFSNHGGLIITVMTHPTTGGVSASFASLGDYNFAEPGALIGFAGRRVIEQT
VREELPEDFQTSEFLLKHGQLDDCISRLDLQNKLSFILSIHVKTPEVGGEADGE

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Escherichia coli, GI1788655, Length=275, Percent_Identity=48.3636363636364, Blast_Score=254, Evalue=7e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 32200; Mature: 32200

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGDLFTKPKKRKYATIPSDGTKADVPEGIMTKCPECKKIMYTKELQKNLMVCNYCGFHH
CCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCEEEEECCCCC
PIGAKARIDMLVDEGSFEEIDASLTTANPLGFEDYMDRIEKDKQKSGLNEAIVTGHATID
CCCCCEEEEEEECCCCHHHHCCHHCCCCCCCHHHHHHHHHHHHHHCCCCHHEEEECEEEC
GNPLVIAVMDSRFRMASMGSVVGEKIFRAVEDADKTNKPFVIFTASGGARMQEGMLSLMQ
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHH
MAKTSAAFKRFSNHGGLIITVMTHPTTGGVSASFASLGDYNFAEPGALIGFAGRRVIEQT
HHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCCCEEEHHHHHHHHHH
VREELPEDFQTSEFLLKHGQLDDCISRLDLQNKLSFILSIHVKTPEVGGEADGE
HHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MLGDLFTKPKKRKYATIPSDGTKADVPEGIMTKCPECKKIMYTKELQKNLMVCNYCGFHH
CCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCEEEEECCCCC
PIGAKARIDMLVDEGSFEEIDASLTTANPLGFEDYMDRIEKDKQKSGLNEAIVTGHATID
CCCCCEEEEEEECCCCHHHHCCHHCCCCCCCHHHHHHHHHHHHHHCCCCHHEEEECEEEC
GNPLVIAVMDSRFRMASMGSVVGEKIFRAVEDADKTNKPFVIFTASGGARMQEGMLSLMQ
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHH
MAKTSAAFKRFSNHGGLIITVMTHPTTGGVSASFASLGDYNFAEPGALIGFAGRRVIEQT
HHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCCCEEEHHHHHHHHHH
VREELPEDFQTSEFLLKHGQLDDCISRLDLQNKLSFILSIHVKTPEVGGEADGE
HHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]