| Definition | Listeria monocytogenes Clip81459, complete genome. |
|---|---|
| Accession | NC_012488 |
| Length | 2,912,690 |
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The map label for this gene is secDF [H]
Identifier: 226224128
GI number: 226224128
Start: 1545677
End: 1547941
Strand: Reverse
Name: secDF [H]
Synonym: Lm4b_01537
Alternate gene names: 226224128
Gene position: 1547941-1545677 (Counterclockwise)
Preceding gene: 226224129
Following gene: 226224127
Centisome position: 53.14
GC content: 38.94
Gene sequence:
>2265_bases ATGGTAAAAAAGAGTAAGATAGTTATTTTCTTTCTAGTAGTTGCAATTATCTTTGGTGCTGTATTTGGTACCGCAAAAAT GGTTATGCAAAACATCAACCTAGGCTTGGATCTTCAAGGGGGATTCGAAGTTCTATATGAAGTTTCACCAGCTGATGGCA AAGGAACTGTATCCAAACAAACATTGACAGATACGGTAACTTCACTCGACAAGCGTATCAATTCATTAGGTGTAGCTGAA CCAAGTATTCAAATCGAAGGGGATAACCGTATTCGTGTTCAACTTGCTGGGGTAACTGATCAGGAAGAAGCACGAAAAAT GCTATCAACCACAGCCCAATTATCATTTAGAGATGCAAATGACAAGATGATGATGAATGGTAGTGACTTAGTTGCGGGCG GTGCCAAACAAGCTTTCGATTCAAGCAACAACCCAATCGTTACGCTAAAACTAAAAAGTGCAGATAAATTTGCTAGTGTA ACAAAAACAATACTAGCGGAAGCGCCTGACAATCAATTAGTTATTTGGTTAGATTGGAAAGAAGGACAAAAATACAAAAC AGAACGCGAGAAGAAAGACCCAGCTTACTTATCAGCACCAAACGTTAGTAGCGTGCTTGATACAGATAAAGTAGAAATTT CCGGAAGTTTCACAACGGAAGAAGCAAAAGATTTAGCTGATTTGCTAAACTCTGGTGCACTCCCTGTTAAAATGAAAGAA GTTTACTCGACATCTGTTGGTGCTCAATTTGGGCAAGATGCGTTACAAGAAACAATTTTAGCTGGTATTATTGGGGTCAT TGCTATCTTTATTTTCATGATGGCAGTTTACCGTTTACCAGGCGTTATTGCTTGTATCACTTTAGTTGCATACACTTATT TAGTACTATTAATACTGAGTCTGCTTAACGCAACACTTACTTTACCAGGGATTGCAGGTTTGATTCTGGGGATAGGTATG GCTGTTGACGCGAACGTAATAACCTACGAGCGGATAAAAGAAGAAATCAAAGTCGGTAGGTCGACGAAAGCGGCTTTTGA GGTCGGCGGTAAAGAAGCATTCCGTGCGATTTTAGATGGTAACTTGACGACACTTATCGTAGCTGCGGTTCTCTTCTACT TTGGAACAAGCTCCATCAAAGGTTTTGCTACGGTTCTAATCATTAGTATTTTAGTCAGCTTCTTGACAGCCGTTTGGGGA TCAAGATTCTTATTAGGCTTATTAGTGAAAAGTAATTGGCTTAACAATAAACCAGGATTCTTTGCAGTTAAACGAAAAGA TATTCATAATTTACATGAGGGAATTAATAGCTTTAGCTTAAAAACACACTTTGATCGCTTTGATTTTGTAAAACATCATC GTCTGTTCTTATCTATTTTTGCTGCAATTGTTATTGTCGGTATTGTTATTCTCTCCATATTTAGGCTAAATCTAGGTATT GACTTTGCCAGTGGGACACGAGCGGAAGTAACAGCTAATCAAACGCTGACAGAAACGCAAATTAAGAAAGATTTAGATGC GATTGATATGCCATCGGATGATATTGTTTTCCAAGGATCAGGGTCTAAAACAGCCGTTGTTTCTTATAAAGGGACATTAT CACAAAATGATGTAGCTAAATTTAAAAACTATTTTGAGGACAAGTATAAGCACGAACCAAGCATTAGTACCGTTTCACCA ACTGTCGGTAAAGAACTTGCCAAAAATGGCTTCTGGGCACTCGGTGTGGCGTCTGTGCTGATTGTACTTTATATTGCAGT CCGGTTTGAATTTTATATGGGTATTGCGGCGATTCTGTCCTTACTATTCGACGCATTTATCATCTTCATATTCTTCAGTG TAACAAGGCTGGAGGTTGACTTAACCTTCATTGCCGCGGTGCTGACGGTTATCGGTTATTCCATTAATGACACGATAGTC ACCGCCGACCGGATACGGGATATTAGTATGAAGATGCAACGTTTCAAAACGAAAGAAGAAATTGCGAATGCGGTTAATAA AGCATTACGCCAAACATTCACTCGTTCAATTAATACCATTTTAACGGTTATTTTCACCGTACTGGCACTTGTACTATTTG GTAGTGAGTCTATTCTGAACTTCTCCATCGCCTTACTTGTTGGACTTGTTTCGAGTGTATTCTCCTCCATCTTTATGGCA ATGCAATTGTGGTACGTATTCAAAGCACGACAACTACGAAAAAAAGGCCCAATTAGCACAGTTAAAAAGAAAAAACCACG TAATAATGGGCAACCTGTCGTATAA
Upstream 100 bases:
>100_bases CAGCCTGTTAGCAAATGCTTGGGTTTCATACATAAAATAGAAGTATTTGTTGTTAGACTGGGATTTGTTATGGTTTAGAT GAGGGAGGAACGAAACAGAA
Downstream 100 bases:
>100_bases AAACGAACGGCCGAATTTCATAAAAAGAGATTCGGTCGTTTTTAATAGCCTAGAAACGGGTAAATAATAAGATAATTGTG CAAGGAGGAGAAAAAACATG
Product: bifunctional preprotein translocase subunit SecD/SecF
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 754; Mature: 754
Protein sequence:
>754_residues MVKKSKIVIFFLVVAIIFGAVFGTAKMVMQNINLGLDLQGGFEVLYEVSPADGKGTVSKQTLTDTVTSLDKRINSLGVAE PSIQIEGDNRIRVQLAGVTDQEEARKMLSTTAQLSFRDANDKMMMNGSDLVAGGAKQAFDSSNNPIVTLKLKSADKFASV TKTILAEAPDNQLVIWLDWKEGQKYKTEREKKDPAYLSAPNVSSVLDTDKVEISGSFTTEEAKDLADLLNSGALPVKMKE VYSTSVGAQFGQDALQETILAGIIGVIAIFIFMMAVYRLPGVIACITLVAYTYLVLLILSLLNATLTLPGIAGLILGIGM AVDANVITYERIKEEIKVGRSTKAAFEVGGKEAFRAILDGNLTTLIVAAVLFYFGTSSIKGFATVLIISILVSFLTAVWG SRFLLGLLVKSNWLNNKPGFFAVKRKDIHNLHEGINSFSLKTHFDRFDFVKHHRLFLSIFAAIVIVGIVILSIFRLNLGI DFASGTRAEVTANQTLTETQIKKDLDAIDMPSDDIVFQGSGSKTAVVSYKGTLSQNDVAKFKNYFEDKYKHEPSISTVSP TVGKELAKNGFWALGVASVLIVLYIAVRFEFYMGIAAILSLLFDAFIIFIFFSVTRLEVDLTFIAAVLTVIGYSINDTIV TADRIRDISMKMQRFKTKEEIANAVNKALRQTFTRSINTILTVIFTVLALVLFGSESILNFSIALLVGLVSSVFSSIFMA MQLWYVFKARQLRKKGPISTVKKKKPRNNGQPVV
Sequences:
>Translated_754_residues MVKKSKIVIFFLVVAIIFGAVFGTAKMVMQNINLGLDLQGGFEVLYEVSPADGKGTVSKQTLTDTVTSLDKRINSLGVAE PSIQIEGDNRIRVQLAGVTDQEEARKMLSTTAQLSFRDANDKMMMNGSDLVAGGAKQAFDSSNNPIVTLKLKSADKFASV TKTILAEAPDNQLVIWLDWKEGQKYKTEREKKDPAYLSAPNVSSVLDTDKVEISGSFTTEEAKDLADLLNSGALPVKMKE VYSTSVGAQFGQDALQETILAGIIGVIAIFIFMMAVYRLPGVIACITLVAYTYLVLLILSLLNATLTLPGIAGLILGIGM AVDANVITYERIKEEIKVGRSTKAAFEVGGKEAFRAILDGNLTTLIVAAVLFYFGTSSIKGFATVLIISILVSFLTAVWG SRFLLGLLVKSNWLNNKPGFFAVKRKDIHNLHEGINSFSLKTHFDRFDFVKHHRLFLSIFAAIVIVGIVILSIFRLNLGI DFASGTRAEVTANQTLTETQIKKDLDAIDMPSDDIVFQGSGSKTAVVSYKGTLSQNDVAKFKNYFEDKYKHEPSISTVSP TVGKELAKNGFWALGVASVLIVLYIAVRFEFYMGIAAILSLLFDAFIIFIFFSVTRLEVDLTFIAAVLTVIGYSINDTIV TADRIRDISMKMQRFKTKEEIANAVNKALRQTFTRSINTILTVIFTVLALVLFGSESILNFSIALLVGLVSSVFSSIFMA MQLWYVFKARQLRKKGPISTVKKKKPRNNGQPVV >Mature_754_residues MVKKSKIVIFFLVVAIIFGAVFGTAKMVMQNINLGLDLQGGFEVLYEVSPADGKGTVSKQTLTDTVTSLDKRINSLGVAE PSIQIEGDNRIRVQLAGVTDQEEARKMLSTTAQLSFRDANDKMMMNGSDLVAGGAKQAFDSSNNPIVTLKLKSADKFASV TKTILAEAPDNQLVIWLDWKEGQKYKTEREKKDPAYLSAPNVSSVLDTDKVEISGSFTTEEAKDLADLLNSGALPVKMKE VYSTSVGAQFGQDALQETILAGIIGVIAIFIFMMAVYRLPGVIACITLVAYTYLVLLILSLLNATLTLPGIAGLILGIGM AVDANVITYERIKEEIKVGRSTKAAFEVGGKEAFRAILDGNLTTLIVAAVLFYFGTSSIKGFATVLIISILVSFLTAVWG SRFLLGLLVKSNWLNNKPGFFAVKRKDIHNLHEGINSFSLKTHFDRFDFVKHHRLFLSIFAAIVIVGIVILSIFRLNLGI DFASGTRAEVTANQTLTETQIKKDLDAIDMPSDDIVFQGSGSKTAVVSYKGTLSQNDVAKFKNYFEDKYKHEPSISTVSP TVGKELAKNGFWALGVASVLIVLYIAVRFEFYMGIAAILSLLFDAFIIFIFFSVTRLEVDLTFIAAVLTVIGYSINDTIV TADRIRDISMKMQRFKTKEEIANAVNKALRQTFTRSINTILTVIFTVLALVLFGSESILNFSIALLVGLVSSVFSSIFMA MQLWYVFKARQLRKKGPISTVKKKKPRNNGQPVV
Specific function: Required for efficient translocation of secretory pre- proteins under conditions of hypersecretion but is not required for the release of mature proteins from the membrane [H]
COG id: COG0342
COG function: function code U; Preprotein translocase subunit SecD
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the secD/secF family. SecF subfamily [H]
Homologues:
Organism=Escherichia coli, GI1786609, Length=373, Percent_Identity=33.2439678284182, Blast_Score=171, Evalue=1e-43, Organism=Escherichia coli, GI1786610, Length=286, Percent_Identity=31.1188811188811, Blast_Score=125, Evalue=1e-29,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005791 - InterPro: IPR022813 - InterPro: IPR022646 - InterPro: IPR022645 - InterPro: IPR005665 [H]
Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]
EC number: NA
Molecular weight: Translated: 82660; Mature: 82660
Theoretical pI: Translated: 9.84; Mature: 9.84
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVKKSKIVIFFLVVAIIFGAVFGTAKMVMQNINLGLDLQGGFEVLYEVSPADGKGTVSKQ CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEEECCCCCCCCCCHH TLTDTVTSLDKRINSLGVAEPSIQIEGDNRIRVQLAGVTDQEEARKMLSTTAQLSFRDAN HHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHEEECCC DKMMMNGSDLVAGGAKQAFDSSNNPIVTLKLKSADKFASVTKTILAEAPDNQLVIWLDWK CCEEECCCCCCCCCCHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECC EGQKYKTEREKKDPAYLSAPNVSSVLDTDKVEISGSFTTEEAKDLADLLNSGALPVKMKE CCCCHHHHHHCCCCCEECCCCHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEHHH VYSTSVGAQFGQDALQETILAGIIGVIAIFIFMMAVYRLPGVIACITLVAYTYLVLLILS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH LLNATLTLPGIAGLILGIGMAVDANVITYERIKEEIKVGRSTKAAFEVGGKEAFRAILDG HHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHCC NLTTLIVAAVLFYFGTSSIKGFATVLIISILVSFLTAVWGSRFLLGLLVKSNWLNNKPGF CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE FAVKRKDIHNLHEGINSFSLKTHFDRFDFVKHHRLFLSIFAAIVIVGIVILSIFRLNLGI EEEEHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC DFASGTRAEVTANQTLTETQIKKDLDAIDMPSDDIVFQGSGSKTAVVSYKGTLSQNDVAK EECCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEEECCCCCHHHHHH FKNYFEDKYKHEPSISTVSPTVGKELAKNGFWALGVASVLIVLYIAVRFEFYMGIAAILS HHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LLFDAFIIFIFFSVTRLEVDLTFIAAVLTVIGYSINDTIVTADRIRDISMKMQRFKTKEE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHCCHHH IANAVNKALRQTFTRSINTILTVIFTVLALVLFGSESILNFSIALLVGLVSSVFSSIFMA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH MQLWYVFKARQLRKKGPISTVKKKKPRNNGQPVV HHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCC >Mature Secondary Structure MVKKSKIVIFFLVVAIIFGAVFGTAKMVMQNINLGLDLQGGFEVLYEVSPADGKGTVSKQ CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEEECCCCCCCCCCHH TLTDTVTSLDKRINSLGVAEPSIQIEGDNRIRVQLAGVTDQEEARKMLSTTAQLSFRDAN HHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHEEECCC DKMMMNGSDLVAGGAKQAFDSSNNPIVTLKLKSADKFASVTKTILAEAPDNQLVIWLDWK CCEEECCCCCCCCCCHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECC EGQKYKTEREKKDPAYLSAPNVSSVLDTDKVEISGSFTTEEAKDLADLLNSGALPVKMKE CCCCHHHHHHCCCCCEECCCCHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEHHH VYSTSVGAQFGQDALQETILAGIIGVIAIFIFMMAVYRLPGVIACITLVAYTYLVLLILS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH LLNATLTLPGIAGLILGIGMAVDANVITYERIKEEIKVGRSTKAAFEVGGKEAFRAILDG HHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHCC NLTTLIVAAVLFYFGTSSIKGFATVLIISILVSFLTAVWGSRFLLGLLVKSNWLNNKPGF CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE FAVKRKDIHNLHEGINSFSLKTHFDRFDFVKHHRLFLSIFAAIVIVGIVILSIFRLNLGI EEEEHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC DFASGTRAEVTANQTLTETQIKKDLDAIDMPSDDIVFQGSGSKTAVVSYKGTLSQNDVAK EECCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEEECCCCCHHHHHH FKNYFEDKYKHEPSISTVSPTVGKELAKNGFWALGVASVLIVLYIAVRFEFYMGIAAILS HHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LLFDAFIIFIFFSVTRLEVDLTFIAAVLTVIGYSINDTIVTADRIRDISMKMQRFKTKEE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHCCHHH IANAVNKALRQTFTRSINTILTVIFTVLALVLFGSESILNFSIALLVGLVSSVFSSIFMA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH MQLWYVFKARQLRKKGPISTVKKKKPRNNGQPVV HHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9694879; 9384377 [H]