Click here to switch to the map view.

The map label for this gene is yclJ [H]

Identifier: 226224108

GI number: 226224108

Start: 1521511

End: 1522197

Strand: Direct

Name: yclJ [H]

Synonym: Lm4b_01517

Alternate gene names: 226224108

Gene position: 1521511-1522197 (Clockwise)

Preceding gene: 226224101

Following gene: 226224109

Centisome position: 52.24

GC content: 36.97

Gene sequence:

>687_bases
ATGAAATTACTTATGATAGAAGATAATGTAAGTGTTTGTGAAATGATAGAAATGTTCTTTATGAAAGAAGAAATTGATGC
TACGTTTGTTCATGACGGCAAGCAGGGTTATGAAGCGTTTTTTAAAGATGAATATGATATTGCAATTATTGACCTAATGC
TTCCTAATATGGACGGTATGACCATTTGCCGTAAAATTCGTGAAGTAAGCGATGTACCAATTATTATTTTAACGGCTAAA
GAATCAGAATCCGATCAAGTGCTTGGCCTTGAAATGGGTGCGGATGATTATGTAACTAAACCATTTAGCCCACTTACTTT
AATGGCGCGAATTAAAGCTGTTACACGCCGCAAAAATAGTGCCACTTCTACAGAAAATAATGAAGATATCCTAGAAACAA
CTTATTTCAAAATTAGTAAACGGACACGAGAAATTTTTTATCAAGGTGAGCTACTTGACGCACTTACGCCAAAAGAATTC
GATTTACTCTATTTTTTGATGCAACATCCACGACAAGTGTTTTCAAGAGAACAATTGCTGGAACAAGTTTGGGGTTATCA
GTTCTATGGAGATGAGCGCACAGTGGACGTTCACATCAAACGTTTACGCCAAAAAATCGCCACCGAAACAAAGCCATTTT
TGCACACCGTCTGGGGTGTTGGCTACAAATTTGATGAAACGGAATGA

Upstream 100 bases:

>100_bases
AACTATGATGCATATTTTAAACTTTCGCGAAAAAAATAATTTGGCTTGATTATTGGGTCTAATTAGGCTAGTTTTAATGT
AAGAGGAGTGAATACAAATT

Downstream 100 bases:

>100_bases
AGCGAATGAAATTTAAATATGCTTACCAATTATTTTTCACACAATTTATCATTTTGCTTATTGCTTGTATCATGATTGGG
GTGCTTGTCTCTCACTCCTT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MKLLMIEDNVSVCEMIEMFFMKEEIDATFVHDGKQGYEAFFKDEYDIAIIDLMLPNMDGMTICRKIREVSDVPIIILTAK
ESESDQVLGLEMGADDYVTKPFSPLTLMARIKAVTRRKNSATSTENNEDILETTYFKISKRTREIFYQGELLDALTPKEF
DLLYFLMQHPRQVFSREQLLEQVWGYQFYGDERTVDVHIKRLRQKIATETKPFLHTVWGVGYKFDETE

Sequences:

>Translated_228_residues
MKLLMIEDNVSVCEMIEMFFMKEEIDATFVHDGKQGYEAFFKDEYDIAIIDLMLPNMDGMTICRKIREVSDVPIIILTAK
ESESDQVLGLEMGADDYVTKPFSPLTLMARIKAVTRRKNSATSTENNEDILETTYFKISKRTREIFYQGELLDALTPKEF
DLLYFLMQHPRQVFSREQLLEQVWGYQFYGDERTVDVHIKRLRQKIATETKPFLHTVWGVGYKFDETE
>Mature_228_residues
MKLLMIEDNVSVCEMIEMFFMKEEIDATFVHDGKQGYEAFFKDEYDIAIIDLMLPNMDGMTICRKIREVSDVPIIILTAK
ESESDQVLGLEMGADDYVTKPFSPLTLMARIKAVTRRKNSATSTENNEDILETTYFKISKRTREIFYQGELLDALTPKEF
DLLYFLMQHPRQVFSREQLLEQVWGYQFYGDERTVDVHIKRLRQKIATETKPFLHTVWGVGYKFDETE

Specific function: Could be member of the two-component regulatory system yclK/yclJ [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=36.5217391304348, Blast_Score=163, Evalue=9e-42,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=36.5217391304348, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=37.4449339207048, Blast_Score=153, Evalue=7e-39,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=35.5263157894737, Blast_Score=140, Evalue=5e-35,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=35.6828193832599, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=34.070796460177, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=36.4035087719298, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=32.6086956521739, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=32.5892857142857, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=29.3859649122807, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=31.4410480349345, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1786911, Length=181, Percent_Identity=34.8066298342541, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=34.4827586206897, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=31.1111111111111, Blast_Score=105, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26731; Mature: 26731

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLMIEDNVSVCEMIEMFFMKEEIDATFVHDGKQGYEAFFKDEYDIAIIDLMLPNMDGM
CEEEEEECCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCEEEEEEECCCCCHH
TICRKIREVSDVPIIILTAKESESDQVLGLEMGADDYVTKPFSPLTLMARIKAVTRRKNS
HHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCC
ATSTENNEDILETTYFKISKRTREIFYQGELLDALTPKEFDLLYFLMQHPRQVFSREQLL
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
EQVWGYQFYGDERTVDVHIKRLRQKIATETKPFLHTVWGVGYKFDETE
HHHHCEEEECCCEEHHHHHHHHHHHHHHCCCHHHHHHHCCCEEECCCC
>Mature Secondary Structure
MKLLMIEDNVSVCEMIEMFFMKEEIDATFVHDGKQGYEAFFKDEYDIAIIDLMLPNMDGM
CEEEEEECCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCEEEEEEECCCCCHH
TICRKIREVSDVPIIILTAKESESDQVLGLEMGADDYVTKPFSPLTLMARIKAVTRRKNS
HHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCC
ATSTENNEDILETTYFKISKRTREIFYQGELLDALTPKEFDLLYFLMQHPRQVFSREQLL
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
EQVWGYQFYGDERTVDVHIKRLRQKIATETKPFLHTVWGVGYKFDETE
HHHHCEEEECCCEEHHHHHHHHHHHHHHCCCHHHHHHHCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]