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The map label for this gene is adhR [H]

Identifier: 226224079

GI number: 226224079

Start: 1495063

End: 1495500

Strand: Direct

Name: adhR [H]

Synonym: Lm4b_01488

Alternate gene names: 226224079

Gene position: 1495063-1495500 (Clockwise)

Preceding gene: 226224062

Following gene: 226224081

Centisome position: 51.33

GC content: 33.79

Gene sequence:

>438_bases
ATGACTTATTCTATTAAAGAAGTGTCCAAAATATTTAATTTGTCGATTTATACATTGCGTTACTATGATAAGCAAGGTTT
ATTGCCGTTTGTTTCTAAAAACCAATCCGGCTACCGTGAGTTTACGGAATCAGACTTAAATTTAATTCATACGATTTGTT
GCTTGAAAAATACAGGAATGTCACTAAAGCAAATCCGCACATATATTGATTATTGTATGGAAGGCCCCGTTTCTATTGAA
GCGCGTAAACAGTTGCTCTTGGATCATCGGGCCGCCGTTTTAAAAAGTTTAGAAGATTTAACAGAAAATCTAAAAGAAGT
CGATGTTAAAATAGCGAAGTATTCGTCTCCTGATGCGGTAGAAATCATTACTGCCGAGAGAAATTATGTCAGTATGGAAA
AGAAAAAGCATGATTTGATTTATCCGTATAATATATAA

Upstream 100 bases:

>100_bases
CAATAGTAGTTAATTTTGCTTATTTCCTTTATTAACTTTATACTTACTTTAAACCCTAGAGTATAGTGTAGGGCAAGTAA
ATTATTTATTGGAGGAAGAA

Downstream 100 bases:

>100_bases
AAAAGTTGTGCCGTGAACATTTCTGTTCACGGCACAACTTTTTTATTATTTGGATTCGTCCATTTTCAAGATTGCCATAA
ATGCTTCTTGCGGGACTTCA

Product: transcriptional regulator (MerR family)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MTYSIKEVSKIFNLSIYTLRYYDKQGLLPFVSKNQSGYREFTESDLNLIHTICCLKNTGMSLKQIRTYIDYCMEGPVSIE
ARKQLLLDHRAAVLKSLEDLTENLKEVDVKIAKYSSPDAVEIITAERNYVSMEKKKHDLIYPYNI

Sequences:

>Translated_145_residues
MTYSIKEVSKIFNLSIYTLRYYDKQGLLPFVSKNQSGYREFTESDLNLIHTICCLKNTGMSLKQIRTYIDYCMEGPVSIE
ARKQLLLDHRAAVLKSLEDLTENLKEVDVKIAKYSSPDAVEIITAERNYVSMEKKKHDLIYPYNI
>Mature_144_residues
TYSIKEVSKIFNLSIYTLRYYDKQGLLPFVSKNQSGYREFTESDLNLIHTICCLKNTGMSLKQIRTYIDYCMEGPVSIEA
RKQLLLDHRAAVLKSLEDLTENLKEVDVKIAKYSSPDAVEIITAERNYVSMEKKKHDLIYPYNI

Specific function: Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon, the yraC and its own promoter region; binding is unchanged in the presence of aldehydes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16856; Mature: 16724

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYSIKEVSKIFNLSIYTLRYYDKQGLLPFVSKNQSGYREFTESDLNLIHTICCLKNTGM
CCCCHHHHHHHHCCCEEEEEEECCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
SLKQIRTYIDYCMEGPVSIEARKQLLLDHRAAVLKSLEDLTENLKEVDVKIAKYSSPDAV
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
EIITAERNYVSMEKKKHDLIYPYNI
EEEECCCCCHHHHHCCCCEECCCCC
>Mature Secondary Structure 
TYSIKEVSKIFNLSIYTLRYYDKQGLLPFVSKNQSGYREFTESDLNLIHTICCLKNTGM
CCCHHHHHHHHCCCEEEEEEECCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
SLKQIRTYIDYCMEGPVSIEARKQLLLDHRAAVLKSLEDLTENLKEVDVKIAKYSSPDAV
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
EIITAERNYVSMEKKKHDLIYPYNI
EEEECCCCCHHHHHCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9384377 [H]