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The map label for this gene is ykpA [H]

Identifier: 226224032

GI number: 226224032

Start: 1445558

End: 1447159

Strand: Direct

Name: ykpA [H]

Synonym: Lm4b_01441

Alternate gene names: 226224032

Gene position: 1445558-1447159 (Clockwise)

Preceding gene: 226224023

Following gene: 226224041

Centisome position: 49.63

GC content: 37.27

Gene sequence:

>1602_bases
ATGTTAACTGTAAATAATGTTGGCTTACGCTACGGCGATAAAAAGCTATTTGAAGATGTTTCGATTAAATTTTTACCAGG
TAACTGTTATGGTCTTATTGGAGCGAATGGTGCTGGTAAATCAACGTTCCTAAAAGTGCTTTCTGGCGAGCTTGATTCAC
AAAGTGGTAATGTGCATATTGGTTCAGGTGAGCGTCTAGCTGTCCTTCGCCAAGATCATTTTCAGTATGATAATGAACTA
GTTCTTAACACAGTAATCATGGGACATGAACGTCTATACAAAATTATGGACGAAAAAAATGCCATTTATATGAAAGAAGA
TTTCAGTGATGAAGATGGTATCCGCGCTGCAGAACTAGAAGGCGAATTTGCTGAATTAGATGGTTGGGAAGCAGAATCTG
ACGCTGCTGTTTTATTAAACGGACTAGGTATCCCTACTGACTTACACGGAAAACTTATGAAAGATTTAACTGGTGGAGAA
AAAGTGAAAGTGCTTCTTGCACAAGCTTTATTCGGTAAACCAGATATCTTACTTCTGGATGAGCCTACCAACCACCTTGA
CATCCGTGCGATTCACTGGTTAGAAGAATTTTTAATCAACTTTGATAATACTGTTATCGTAGTATCCCATGACCGTCACT
TCTTAAATAAAGTGTGTACGCACATTGCGGATCTTGATTTCAGCAAAATTAAATTATATGTCGGAAACTATGATTTCTGG
TATGAATCAAGCCAATTAGCTCAAACAATGATGGGCGATCGTAACAAGAAAAAAGAAGAAAAAATGAAAGAATTACAAGA
CTTTATTGCTCGTTTCAGTGCGAACGCATCGAAATCAAAACAAGCAACAAGTCGTAAAAAAATGCTCGAAAAAATCACGC
TGGAAGATATTCAACCTTCTAGTCGTCGTTACCCTTTCATTCAGTTCAAACCAGACCGTGAAGTTGGAAATGACCTTCTA
ACAGTAACAAACTTGTCTAAAACAATCGATGGTGTGAAGATTCTTGATAATCTTTCTTTCTCGATTAATCGAAATGACAA
AGTTGCTTTAGTTGGCGATGATGAGGTTGCTAAAACAGTTCTTTTCCAAATCCTTGCTGGTGAAATGGAACCTGATGAGG
GTAGTTATAAATGGGGAATTACAACAAGCCAAAGCTATTTCCCGAAAGATAACTCAGAGTTCTTTGAAGAAAACGACATG
AGTCTTGTAGAATGGTTACGTCAATTCTCTCCAGAAGATGACAGTGAAGCATTCTTACGCGGCTTCCTTGGTCGTATGCT
ATTCAGTGGCGATGAAGTACTTAAAAAAGTACGCGTCTTATCTGGTGGAGAAAAAGTTCGTTGTATGTTATCCAAAATGA
TGCTTTCAGGTTCTAACGTTCTTTTACTAGACGAACCTACTAACCACTTGGACTTAGAATCCATTACAGCATTGAATAAC
GGCTTGGAAGCATTTAAAGGCGCAATGATTTTTGCTTCTCATGATCATCAGTTATTACAAACAATCGCAACGCGCATCAT
TAACTTATCAAAAGACCAATTTTACAATAAAGAAATTTCTTATGATGAGTATCTAAAAGAAGTAATGAACGTAGCAGAAT
AA

Upstream 100 bases:

>100_bases
ATGTGTGTATGCTTTCTTTGCTACACTAACCATGTTAAAATAGTAGTAATTGTGCTTTTTCTGATTTCAAGAAGAAGTAA
CTTAGTATTGGAGGAAGAAA

Downstream 100 bases:

>100_bases
TGACAAAAAAACAATATCCCATTTTCGGGATATTGTTTTTATTTTAGTTCGATTTTGCCAGTTTCTGTCGTGATTGGTGT
GGATGAATCTTTCAGATAGC

Product: ABC transporter (ATP-binding protein)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MLTVNNVGLRYGDKKLFEDVSIKFLPGNCYGLIGANGAGKSTFLKVLSGELDSQSGNVHIGSGERLAVLRQDHFQYDNEL
VLNTVIMGHERLYKIMDEKNAIYMKEDFSDEDGIRAAELEGEFAELDGWEAESDAAVLLNGLGIPTDLHGKLMKDLTGGE
KVKVLLAQALFGKPDILLLDEPTNHLDIRAIHWLEEFLINFDNTVIVVSHDRHFLNKVCTHIADLDFSKIKLYVGNYDFW
YESSQLAQTMMGDRNKKKEEKMKELQDFIARFSANASKSKQATSRKKMLEKITLEDIQPSSRRYPFIQFKPDREVGNDLL
TVTNLSKTIDGVKILDNLSFSINRNDKVALVGDDEVAKTVLFQILAGEMEPDEGSYKWGITTSQSYFPKDNSEFFEENDM
SLVEWLRQFSPEDDSEAFLRGFLGRMLFSGDEVLKKVRVLSGGEKVRCMLSKMMLSGSNVLLLDEPTNHLDLESITALNN
GLEAFKGAMIFASHDHQLLQTIATRIINLSKDQFYNKEISYDEYLKEVMNVAE

Sequences:

>Translated_533_residues
MLTVNNVGLRYGDKKLFEDVSIKFLPGNCYGLIGANGAGKSTFLKVLSGELDSQSGNVHIGSGERLAVLRQDHFQYDNEL
VLNTVIMGHERLYKIMDEKNAIYMKEDFSDEDGIRAAELEGEFAELDGWEAESDAAVLLNGLGIPTDLHGKLMKDLTGGE
KVKVLLAQALFGKPDILLLDEPTNHLDIRAIHWLEEFLINFDNTVIVVSHDRHFLNKVCTHIADLDFSKIKLYVGNYDFW
YESSQLAQTMMGDRNKKKEEKMKELQDFIARFSANASKSKQATSRKKMLEKITLEDIQPSSRRYPFIQFKPDREVGNDLL
TVTNLSKTIDGVKILDNLSFSINRNDKVALVGDDEVAKTVLFQILAGEMEPDEGSYKWGITTSQSYFPKDNSEFFEENDM
SLVEWLRQFSPEDDSEAFLRGFLGRMLFSGDEVLKKVRVLSGGEKVRCMLSKMMLSGSNVLLLDEPTNHLDLESITALNN
GLEAFKGAMIFASHDHQLLQTIATRIINLSKDQFYNKEISYDEYLKEVMNVAE
>Mature_533_residues
MLTVNNVGLRYGDKKLFEDVSIKFLPGNCYGLIGANGAGKSTFLKVLSGELDSQSGNVHIGSGERLAVLRQDHFQYDNEL
VLNTVIMGHERLYKIMDEKNAIYMKEDFSDEDGIRAAELEGEFAELDGWEAESDAAVLLNGLGIPTDLHGKLMKDLTGGE
KVKVLLAQALFGKPDILLLDEPTNHLDIRAIHWLEEFLINFDNTVIVVSHDRHFLNKVCTHIADLDFSKIKLYVGNYDFW
YESSQLAQTMMGDRNKKKEEKMKELQDFIARFSANASKSKQATSRKKMLEKITLEDIQPSSRRYPFIQFKPDREVGNDLL
TVTNLSKTIDGVKILDNLSFSINRNDKVALVGDDEVAKTVLFQILAGEMEPDEGSYKWGITTSQSYFPKDNSEFFEENDM
SLVEWLRQFSPEDDSEAFLRGFLGRMLFSGDEVLKKVRVLSGGEKVRCMLSKMMLSGSNVLLLDEPTNHLDLESITALNN
GLEAFKGAMIFASHDHQLLQTIATRIINLSKDQFYNKEISYDEYLKEVMNVAE

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=529, Percent_Identity=29.6786389413989, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI10947137, Length=533, Percent_Identity=32.6454033771107, Blast_Score=242, Evalue=6e-64,
Organism=Homo sapiens, GI27881506, Length=533, Percent_Identity=32.6454033771107, Blast_Score=242, Evalue=6e-64,
Organism=Homo sapiens, GI69354671, Length=546, Percent_Identity=27.8388278388278, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI10947135, Length=546, Percent_Identity=27.8388278388278, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI105990541, Length=207, Percent_Identity=28.5024154589372, Blast_Score=77, Evalue=6e-14,
Organism=Escherichia coli, GI1787041, Length=526, Percent_Identity=46.0076045627376, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI1789751, Length=504, Percent_Identity=34.1269841269841, Blast_Score=279, Evalue=4e-76,
Organism=Escherichia coli, GI2367384, Length=555, Percent_Identity=32.4324324324324, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI1787182, Length=509, Percent_Identity=27.5049115913556, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1786398, Length=211, Percent_Identity=26.0663507109005, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI87081709, Length=257, Percent_Identity=24.5136186770428, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1787029, Length=233, Percent_Identity=24.0343347639485, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786703, Length=198, Percent_Identity=31.3131313131313, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789864, Length=219, Percent_Identity=23.7442922374429, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=544, Percent_Identity=32.1691176470588, Blast_Score=248, Evalue=7e-66,
Organism=Caenorhabditis elegans, GI17555318, Length=512, Percent_Identity=29.1015625, Blast_Score=215, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI17559834, Length=553, Percent_Identity=27.3056057866184, Blast_Score=208, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17558664, Length=216, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17565938, Length=187, Percent_Identity=26.7379679144385, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=527, Percent_Identity=33.7760910815939, Blast_Score=247, Evalue=3e-66,
Organism=Saccharomyces cerevisiae, GI6321121, Length=528, Percent_Identity=28.4090909090909, Blast_Score=209, Evalue=6e-55,
Organism=Saccharomyces cerevisiae, GI6325030, Length=420, Percent_Identity=26.9047619047619, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6324314, Length=368, Percent_Identity=24.7282608695652, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323278, Length=366, Percent_Identity=25.9562841530055, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24666836, Length=537, Percent_Identity=31.6573556797021, Blast_Score=250, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24642252, Length=519, Percent_Identity=30.635838150289, Blast_Score=225, Evalue=6e-59,
Organism=Drosophila melanogaster, GI18859989, Length=519, Percent_Identity=30.635838150289, Blast_Score=225, Evalue=6e-59,
Organism=Drosophila melanogaster, GI24641342, Length=546, Percent_Identity=29.4871794871795, Blast_Score=216, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 60316; Mature: 60316

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTVNNVGLRYGDKKLFEDVSIKFLPGNCYGLIGANGAGKSTFLKVLSGELDSQSGNVHI
CEEEECCCCCCCCHHHHCCCEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEE
GSGERLAVLRQDHFQYDNELVLNTVIMGHERLYKIMDEKNAIYMKEDFSDEDGIRAAELE
CCCCEEEEEEHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECC
GEFAELDGWEAESDAAVLLNGLGIPTDLHGKLMKDLTGGEKVKVLLAQALFGKPDILLLD
CCHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEE
EPTNHLDIRAIHWLEEFLINFDNTVIVVSHDRHFLNKVCTHIADLDFSKIKLYVGNYDFW
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEEEECCEEEE
YESSQLAQTMMGDRNKKKEEKMKELQDFIARFSANASKSKQATSRKKMLEKITLEDIQPS
ECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC
SRRYPFIQFKPDREVGNDLLTVTNLSKTIDGVKILDNLSFSINRNDKVALVGDDEVAKTV
CCCCCEEEECCCHHHCCCEEEEEHHHHHHCCHHHHHCCEEEECCCCEEEEECCHHHHHHH
LFQILAGEMEPDEGSYKWGITTSQSYFPKDNSEFFEENDMSLVEWLRQFSPEDDSEAFLR
HHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCHHHHHH
GFLGRMLFSGDEVLKKVRVLSGGEKVRCMLSKMMLSGSNVLLLDEPTNHLDLESITALNN
HHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
GLEAFKGAMIFASHDHQLLQTIATRIINLSKDQFYNKEISYDEYLKEVMNVAE
HHHHHCCEEEEECCCHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLTVNNVGLRYGDKKLFEDVSIKFLPGNCYGLIGANGAGKSTFLKVLSGELDSQSGNVHI
CEEEECCCCCCCCHHHHCCCEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEE
GSGERLAVLRQDHFQYDNELVLNTVIMGHERLYKIMDEKNAIYMKEDFSDEDGIRAAELE
CCCCEEEEEEHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECC
GEFAELDGWEAESDAAVLLNGLGIPTDLHGKLMKDLTGGEKVKVLLAQALFGKPDILLLD
CCHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEE
EPTNHLDIRAIHWLEEFLINFDNTVIVVSHDRHFLNKVCTHIADLDFSKIKLYVGNYDFW
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEEEECCEEEE
YESSQLAQTMMGDRNKKKEEKMKELQDFIARFSANASKSKQATSRKKMLEKITLEDIQPS
ECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC
SRRYPFIQFKPDREVGNDLLTVTNLSKTIDGVKILDNLSFSINRNDKVALVGDDEVAKTV
CCCCCEEEECCCHHHCCCEEEEEHHHHHHCCHHHHHCCEEEECCCCEEEEECCHHHHHHH
LFQILAGEMEPDEGSYKWGITTSQSYFPKDNSEFFEENDMSLVEWLRQFSPEDDSEAFLR
HHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCHHHHHH
GFLGRMLFSGDEVLKKVRVLSGGEKVRCMLSKMMLSGSNVLLLDEPTNHLDLESITALNN
HHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
GLEAFKGAMIFASHDHQLLQTIATRIINLSKDQFYNKEISYDEYLKEVMNVAE
HHHHHCCEEEEECCCHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]