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The map label for this gene is opuCB [H]

Identifier: 226224023

GI number: 226224023

Start: 1436489

End: 1438003

Strand: Direct

Name: opuCB [H]

Synonym: Lm4b_01431

Alternate gene names: 226224023

Gene position: 1436489-1438003 (Clockwise)

Preceding gene: 226224022

Following gene: 226224032

Centisome position: 49.32

GC content: 35.51

Gene sequence:

>1515_bases
ATGAATACTCTTATAGATACATTTACTGTCCGTAAAGATGAACTATTCACAGCTTTAGTACAACATATTCAAATTTCCTT
TGTCTCTCTTTTTATAGCGGTGTTAATTGCCTTACCTCTTGGGATTTATTTAACTAGACATAAGCGTCTCGCTGAACCAA
TTATTCAAGTAGCCGCTATTTTTCAAACAATTCCTTCTCTGGCACTACTTGGTTTGTTAATTCCGCTCGTTGGTATTGGG
ATAGTTCCAGCGATTATTGCGCTTGTTATTTACGCCCTCTTACCTATTTTAAGGAATACATATACTGGGATAAAAGAAGT
CGACCCAGCCCTTGTTGAAGCCTCACGCGCAATGGGAATGAACAAATGGAAAAGATTATACAAAGTAGAACTTCCTCTTG
CTATGCCAGTAATTATGGCTGGTATTCGTACAGCGATGGTATTAATCATCGGTACAGCGACACTTGCTGCTTTAATTGGT
GCAGGTGGACTCGGGGACTTGATTCTACTAGGGATTGACCGCAATGATAATAGTTTAATTCTATTAGGTGCAATTCCAGC
AGCGTTACTAGCGATTTTGTTTGATTTCTTACTACGTTTCCTTGAAAAAGCATCTTTTAAAAGCACAATTATTACGATTT
CAGCAGGTATCTTATTAACTGCCGCAATTATCGTCGTTCCTTATTTTGCGTCTGATAAAAAAGAAATTACGATTGCAGGT
AAATTAGGTGCAGAACCAGAAATTTTGATTAATATGTACAAACTAGTTATTGAGGACGAAACAGATTTAAAAGTTAATGT
GAAGCCGAATATGGGTAAAACGAGCTTCGTTTTTAATGCATTAAAATCAGGTGATATTGATATTTATCCTGAATTTACAG
GAACAGTGCTAGAGACATTCTTAAAAGAAAATGCAAAAACACATGATCCTGAAGAAGTGTATACGCAAGCACGTGATGGT
TTGGCAAAAGATTTTAATATGTCTTATTTAAAACCGATGAAATATAATAACACCTATGCTCTTGCGGTTTCACCAGAATT
TGCAAAAGAAAATAATTTAGAAAAAATATCTGATCTTGGCCCAGTATCTGACCAAGTAAAAGCTGGATTCACACTGGAGT
TTAAAGACCGTTCGGATGGTTATAAAGGGATTCAAGATAAATATGGTCTCACATTCTCTAACTTGAAAACAATGGAGCCA
AAACTGCGATATAATGCAATTAAATCTGGAGACATCAATTTACTAGATGCTTACTCAACAGATAGTGAACTCGCCCAATA
TAAATTAAAAGTCCTAGAAGACGATCAGCAGCTCTTCCCTCCTTATCAAGGTGCACCGCTTATGCTGACAAAAACATTAG
AAAAATACCCAGAACTGAAAAAACCATTAAATAAACTAGCTGGGAAAATTACAGATGATGAAATGCGTAAAATGAATTAT
GAAGTGAATGTAAATGGCAAATCAGCTTATACAGTTGCCAAAGACTATTTGAAAGATCAAGGTATTATTAAATAA

Upstream 100 bases:

>100_bases
TTCCTGTCACAGACGAAGCAGGTAATTTTATCGGTACAGTTTCAAATAAACATGTGATGCAATTCTTAGCGCGTCATCTG
GAAAGTTCAGGTGAGCTTGT

Downstream 100 bases:

>100_bases
AAAAGCGAAGTGGTTTTTACGCCACTTCGCTTTTTTTATTGTCTAATTAAGTTTTTGACTTTATTAATGTTTGGTTTGTA
AAAACGACAATGTGTTTCAA

Product: glycine betaine/carnitine/choline ABC transporter (membrane protein)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MNTLIDTFTVRKDELFTALVQHIQISFVSLFIAVLIALPLGIYLTRHKRLAEPIIQVAAIFQTIPSLALLGLLIPLVGIG
IVPAIIALVIYALLPILRNTYTGIKEVDPALVEASRAMGMNKWKRLYKVELPLAMPVIMAGIRTAMVLIIGTATLAALIG
AGGLGDLILLGIDRNDNSLILLGAIPAALLAILFDFLLRFLEKASFKSTIITISAGILLTAAIIVVPYFASDKKEITIAG
KLGAEPEILINMYKLVIEDETDLKVNVKPNMGKTSFVFNALKSGDIDIYPEFTGTVLETFLKENAKTHDPEEVYTQARDG
LAKDFNMSYLKPMKYNNTYALAVSPEFAKENNLEKISDLGPVSDQVKAGFTLEFKDRSDGYKGIQDKYGLTFSNLKTMEP
KLRYNAIKSGDINLLDAYSTDSELAQYKLKVLEDDQQLFPPYQGAPLMLTKTLEKYPELKKPLNKLAGKITDDEMRKMNY
EVNVNGKSAYTVAKDYLKDQGIIK

Sequences:

>Translated_504_residues
MNTLIDTFTVRKDELFTALVQHIQISFVSLFIAVLIALPLGIYLTRHKRLAEPIIQVAAIFQTIPSLALLGLLIPLVGIG
IVPAIIALVIYALLPILRNTYTGIKEVDPALVEASRAMGMNKWKRLYKVELPLAMPVIMAGIRTAMVLIIGTATLAALIG
AGGLGDLILLGIDRNDNSLILLGAIPAALLAILFDFLLRFLEKASFKSTIITISAGILLTAAIIVVPYFASDKKEITIAG
KLGAEPEILINMYKLVIEDETDLKVNVKPNMGKTSFVFNALKSGDIDIYPEFTGTVLETFLKENAKTHDPEEVYTQARDG
LAKDFNMSYLKPMKYNNTYALAVSPEFAKENNLEKISDLGPVSDQVKAGFTLEFKDRSDGYKGIQDKYGLTFSNLKTMEP
KLRYNAIKSGDINLLDAYSTDSELAQYKLKVLEDDQQLFPPYQGAPLMLTKTLEKYPELKKPLNKLAGKITDDEMRKMNY
EVNVNGKSAYTVAKDYLKDQGIIK
>Mature_504_residues
MNTLIDTFTVRKDELFTALVQHIQISFVSLFIAVLIALPLGIYLTRHKRLAEPIIQVAAIFQTIPSLALLGLLIPLVGIG
IVPAIIALVIYALLPILRNTYTGIKEVDPALVEASRAMGMNKWKRLYKVELPLAMPVIMAGIRTAMVLIIGTATLAALIG
AGGLGDLILLGIDRNDNSLILLGAIPAALLAILFDFLLRFLEKASFKSTIITISAGILLTAAIIVVPYFASDKKEITIAG
KLGAEPEILINMYKLVIEDETDLKVNVKPNMGKTSFVFNALKSGDIDIYPEFTGTVLETFLKENAKTHDPEEVYTQARDG
LAKDFNMSYLKPMKYNNTYALAVSPEFAKENNLEKISDLGPVSDQVKAGFTLEFKDRSDGYKGIQDKYGLTFSNLKTMEP
KLRYNAIKSGDINLLDAYSTDSELAQYKLKVLEDDQQLFPPYQGAPLMLTKTLEKYPELKKPLNKLAGKITDDEMRKMNY
EVNVNGKSAYTVAKDYLKDQGIIK

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1732

COG function: function code M; Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788451, Length=220, Percent_Identity=38.6363636363636, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1788449, Length=199, Percent_Identity=40.7035175879397, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1789033, Length=173, Percent_Identity=40.4624277456647, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1788452, Length=309, Percent_Identity=27.5080906148867, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 55697; Mature: 55697

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLIDTFTVRKDELFTALVQHIQISFVSLFIAVLIALPLGIYLTRHKRLAEPIIQVAAI
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQTIPSLALLGLLIPLVGIGIVPAIIALVIYALLPILRNTYTGIKEVDPALVEASRAMGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHCCH
NKWKRLYKVELPLAMPVIMAGIRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNDNSLI
HHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEE
LLGAIPAALLAILFDFLLRFLEKASFKSTIITISAGILLTAAIIVVPYFASDKKEITIAG
EEECHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCEEEEEE
KLGAEPEILINMYKLVIEDETDLKVNVKPNMGKTSFVFNALKSGDIDIYPEFTGTVLETF
CCCCCHHHHHHHHHHHEECCCCEEEEECCCCCCHHHHHHHHCCCCEEEECCHHHHHHHHH
LKENAKTHDPEEVYTQARDGLAKDFNMSYLKPMKYNNTYALAVSPEFAKENNLEKISDLG
HHCCCCCCCHHHHHHHHHCCCCCCCCCHHCCCEECCCEEEEEECCCHHCCCCHHHHHHCC
PVSDQVKAGFTLEFKDRSDGYKGIQDKYGLTFSNLKTMEPKLRYNAIKSGDINLLDAYST
CCCHHHHCCEEEEECCCCCCCCCCHHHCCCCHHCCHHCCCHHHHCCCCCCCCEEEECCCC
DSELAQYKLKVLEDDQQLFPPYQGAPLMLTKTLEKYPELKKPLNKLAGKITDDEMRKMNY
HHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHCCC
EVNVNGKSAYTVAKDYLKDQGIIK
EEEECCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNTLIDTFTVRKDELFTALVQHIQISFVSLFIAVLIALPLGIYLTRHKRLAEPIIQVAAI
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQTIPSLALLGLLIPLVGIGIVPAIIALVIYALLPILRNTYTGIKEVDPALVEASRAMGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHCCH
NKWKRLYKVELPLAMPVIMAGIRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNDNSLI
HHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEE
LLGAIPAALLAILFDFLLRFLEKASFKSTIITISAGILLTAAIIVVPYFASDKKEITIAG
EEECHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCEEEEEE
KLGAEPEILINMYKLVIEDETDLKVNVKPNMGKTSFVFNALKSGDIDIYPEFTGTVLETF
CCCCCHHHHHHHHHHHEECCCCEEEEECCCCCCHHHHHHHHCCCCEEEECCHHHHHHHHH
LKENAKTHDPEEVYTQARDGLAKDFNMSYLKPMKYNNTYALAVSPEFAKENNLEKISDLG
HHCCCCCCCHHHHHHHHHCCCCCCCCCHHCCCEECCCEEEEEECCCHHCCCCHHHHHHCC
PVSDQVKAGFTLEFKDRSDGYKGIQDKYGLTFSNLKTMEPKLRYNAIKSGDINLLDAYST
CCCHHHHCCEEEEECCCCCCCCCCHHHCCCCHHCCHHCCCHHHHCCCCCCCCEEEECCCC
DSELAQYKLKVLEDDQQLFPPYQGAPLMLTKTLEKYPELKKPLNKLAGKITDDEMRKMNY
HHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHCCC
EVNVNGKSAYTVAKDYLKDQGIIK
EEEECCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]