Click here to switch to the map view.

The map label for this gene is 226224000

Identifier: 226224000

GI number: 226224000

Start: 1410469

End: 1412031

Strand: Direct

Name: 226224000

Synonym: Lm4b_01408

Alternate gene names: NA

Gene position: 1410469-1412031 (Clockwise)

Preceding gene: 226223999

Following gene: 226224001

Centisome position: 48.42

GC content: 41.59

Gene sequence:

>1563_bases
ATGACAATCGCAATCACGATCATCTCCAGTTTGCTTTTCTTAATCGTCGGTCTAGTTGTTGGTTCTCTAATTTTTAAATC
TAGTACAGAGAAAAAACTGGCTGCTGCAAGGGGGACTGCGGAATTAATTGTAGAGGATGCGAAGAAAGAAGCAGAAACTA
CAAAAAAAGAAGCATTGCTTGAAGCGAAGGAAGAGAATCATAGGTTACGTACTGAAATCGAAAATGAACTTCGTGGGCGA
AGAACAGAGACACAGAAAGCAGAAAATCGCTTATTGCAAAGGGAGGAAAACCTCGACCGTAAAGATACTTCTTTAAGTAA
ACGAGAAGCTACACTTGAAAGAAAAGAGGAGAGTATCAGTAAACGTCAACAACAAATTGAAGAGAAAGAAAGCAAACTAG
CTGAGATGATTCAAGCGGAGCAGACAGAACTCGAAAGAATTTCTGCGCTCAGCAAAGAGGAAGCGAAATCTATCATCCTT
AACCAGGTAGAAGAGGAATTAACACATGATACAGCAATCATGGTCAAAGAATCAGAAAACCGGGCCAAGGAAGAGTCGGA
TAAAAAAGCAAAGAATATTCTCTCACTAGCTATCCAGCGTTGTGCAGCTGATCATGTGGCAGAAACAACGGTATCTGTTG
TTACCTTACCAAATGATGAGATGAAAGGTCGGATTATCGGACGTGAAGGCCGTAATATCCGCACGCTTGAGACGTTAACG
GGGATTGATTTGATAATTGATGATACACCGGAAGCAGTAATTCTTTCCGGATTTGATCCAATTCGACGTGAAATCGCTAG
AATCGCCTTAGAAAAACTTGTTCAAGATGGAAGAATCCATCCAGCTCGAATTGAAGAAATGGTGGACAAAGCCCGTAAAG
AGGTGGACGAACACATTCGCGAAGTCGGGGAACAAGCAACATTTGAAGTTGGAATTCATTCCATCCATCCTGATTTGATA
AAAATTCTTGGCCGCTTGCGTTACCGTACTAGTTACGGACAAAACGTTCTTAACCACTCACTCGAAGTTTCAAAACTTGC
AGGAATTCTTGCAGGAGAGCTTGGCGAAGACGTTACGCTTGCTAAACGGGCCGGACTACTTCATGACATCGGGAAAGCAA
TTGACCATGAAATTGAAGGCAGTCATGTTGAAATCGGCGTGGAACTTGCTACCAAATACAAAGAAAATGATGTGGTAATC
AATAGTATTGCTTCCCATCACGGAGATACAGAAGCTACTTCTGTTATCGCAGTATTGGTCGCAGCGGCAGATGCACTTTC
TGCTGCAAGACCGGGAGCTCGTAGTGAAACGCTTGAAAATTACATCCGTCGTTTAGAAAAATTAGAAGAAATTTCTGAGT
CTTACGATGGTGTAGAAAAATCTTATGCTATCCAAGCAGGACGTGAAGTACGTATCATCGTTGAACCAGATACAATTGAT
GATCTTTCTTCTTACCGCCTTGCTCGCGACATAAGAAAACGAATTGAAGAGGAATTAGATTATCCTGGTCACATTAAAGT
GACTGTCATTCGTGAAACAAGAGCAGTTGAATACGCTAAATAA

Upstream 100 bases:

>100_bases
GGAGATTAGCACTCGGTTGTTGATGAAAAATACGCATGTGCCAGAATTCTGGCCACCGACATAACAATAACGAAAATTGA
ATAGCAAAGGAGGTGTAAGG

Downstream 100 bases:

>100_bases
TAATTAAAAGATACATCGCAAATTTATTTTGCGGTGTATCTTTTTTTAATCGGTTGCCTAGGTCGAGTAAGAACGGTATA
ATTAATGGATAAACGAAAAA

Product: phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MTIAITIISSLLFLIVGLVVGSLIFKSSTEKKLAAARGTAELIVEDAKKEAETTKKEALLEAKEENHRLRTEIENELRGR
RTETQKAENRLLQREENLDRKDTSLSKREATLERKEESISKRQQQIEEKESKLAEMIQAEQTELERISALSKEEAKSIIL
NQVEEELTHDTAIMVKESENRAKEESDKKAKNILSLAIQRCAADHVAETTVSVVTLPNDEMKGRIIGREGRNIRTLETLT
GIDLIIDDTPEAVILSGFDPIRREIARIALEKLVQDGRIHPARIEEMVDKARKEVDEHIREVGEQATFEVGIHSIHPDLI
KILGRLRYRTSYGQNVLNHSLEVSKLAGILAGELGEDVTLAKRAGLLHDIGKAIDHEIEGSHVEIGVELATKYKENDVVI
NSIASHHGDTEATSVIAVLVAAADALSAARPGARSETLENYIRRLEKLEEISESYDGVEKSYAIQAGREVRIIVEPDTID
DLSSYRLARDIRKRIEEELDYPGHIKVTVIRETRAVEYAK

Sequences:

>Translated_520_residues
MTIAITIISSLLFLIVGLVVGSLIFKSSTEKKLAAARGTAELIVEDAKKEAETTKKEALLEAKEENHRLRTEIENELRGR
RTETQKAENRLLQREENLDRKDTSLSKREATLERKEESISKRQQQIEEKESKLAEMIQAEQTELERISALSKEEAKSIIL
NQVEEELTHDTAIMVKESENRAKEESDKKAKNILSLAIQRCAADHVAETTVSVVTLPNDEMKGRIIGREGRNIRTLETLT
GIDLIIDDTPEAVILSGFDPIRREIARIALEKLVQDGRIHPARIEEMVDKARKEVDEHIREVGEQATFEVGIHSIHPDLI
KILGRLRYRTSYGQNVLNHSLEVSKLAGILAGELGEDVTLAKRAGLLHDIGKAIDHEIEGSHVEIGVELATKYKENDVVI
NSIASHHGDTEATSVIAVLVAAADALSAARPGARSETLENYIRRLEKLEEISESYDGVEKSYAIQAGREVRIIVEPDTID
DLSSYRLARDIRKRIEEELDYPGHIKVTVIRETRAVEYAK
>Mature_519_residues
TIAITIISSLLFLIVGLVVGSLIFKSSTEKKLAAARGTAELIVEDAKKEAETTKKEALLEAKEENHRLRTEIENELRGRR
TETQKAENRLLQREENLDRKDTSLSKREATLERKEESISKRQQQIEEKESKLAEMIQAEQTELERISALSKEEAKSIILN
QVEEELTHDTAIMVKESENRAKEESDKKAKNILSLAIQRCAADHVAETTVSVVTLPNDEMKGRIIGREGRNIRTLETLTG
IDLIIDDTPEAVILSGFDPIRREIARIALEKLVQDGRIHPARIEEMVDKARKEVDEHIREVGEQATFEVGIHSIHPDLIK
ILGRLRYRTSYGQNVLNHSLEVSKLAGILAGELGEDVTLAKRAGLLHDIGKAIDHEIEGSHVEIGVELATKYKENDVVIN
SIASHHGDTEATSVIAVLVAAADALSAARPGARSETLENYIRRLEKLEEISESYDGVEKSYAIQAGREVRIIVEPDTIDD
LSSYRLARDIRKRIEEELDYPGHIKVTVIRETRAVEYAK

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CNPD_LISIN (P0A4Q7)

Other databases:

- EMBL:   AL596168
- PIR:   AC1612
- RefSeq:   NP_470772.1
- ProteinModelPortal:   P0A4Q7
- GeneID:   1130036
- GenomeReviews:   AL592022_GR
- KEGG:   lin:lin1436
- GenoList:   LIN1436
- HOGENOM:   HBG734610
- OMA:   HPGRIEE
- ProtClustDB:   PRK12704
- BioCyc:   LINN272626:LIN1436-MONOMER
- HAMAP:   MF_00335
- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675
- SMART:   SM00471
- SMART:   SM00322
- TIGRFAMs:   TIGR00277
- TIGRFAMs:   TIGR03319

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1

EC number: =3.1.4.16

Molecular weight: Translated: 58319; Mature: 58188

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1ebcfd18)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAITIISSLLFLIVGLVVGSLIFKSSTEKKLAAARGTAELIVEDAKKEAETTKKEALL
CEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
EAKEENHRLRTEIENELRGRRTETQKAENRLLQREENLDRKDTSLSKREATLERKEESIS
HHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHHH
KRQQQIEEKESKLAEMIQAEQTELERISALSKEEAKSIILNQVEEELTHDTAIMVKESEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHH
RAKEESDKKAKNILSLAIQRCAADHVAETTVSVVTLPNDEMKGRIIGREGRNIRTLETLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEECCCCCCEEHHHHHC
GIDLIIDDTPEAVILSGFDPIRREIARIALEKLVQDGRIHPARIEEMVDKARKEVDEHIR
CCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
EVGEQATFEVGIHSIHPDLIKILGRLRYRTSYGQNVLNHSLEVSKLAGILAGELGEDVTL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AKRAGLLHDIGKAIDHEIEGSHVEIGVELATKYKENDVVINSIASHHGDTEATSVIAVLV
HHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHH
AAADALSAARPGARSETLENYIRRLEKLEEISESYDGVEKSYAIQAGREVRIIVEPDTID
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCH
DLSSYRLARDIRKRIEEELDYPGHIKVTVIRETRAVEYAK
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCH
>Mature Secondary Structure 
TIAITIISSLLFLIVGLVVGSLIFKSSTEKKLAAARGTAELIVEDAKKEAETTKKEALL
EEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
EAKEENHRLRTEIENELRGRRTETQKAENRLLQREENLDRKDTSLSKREATLERKEESIS
HHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHHH
KRQQQIEEKESKLAEMIQAEQTELERISALSKEEAKSIILNQVEEELTHDTAIMVKESEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHH
RAKEESDKKAKNILSLAIQRCAADHVAETTVSVVTLPNDEMKGRIIGREGRNIRTLETLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEECCCCCCEEHHHHHC
GIDLIIDDTPEAVILSGFDPIRREIARIALEKLVQDGRIHPARIEEMVDKARKEVDEHIR
CCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
EVGEQATFEVGIHSIHPDLIKILGRLRYRTSYGQNVLNHSLEVSKLAGILAGELGEDVTL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AKRAGLLHDIGKAIDHEIEGSHVEIGVELATKYKENDVVINSIASHHGDTEATSVIAVLV
HHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHH
AAADALSAARPGARSETLENYIRRLEKLEEISESYDGVEKSYAIQAGREVRIIVEPDTID
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCH
DLSSYRLARDIRKRIEEELDYPGHIKVTVIRETRAVEYAK
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11679669