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The map label for this gene is glcK [H]

Identifier: 226223940

GI number: 226223940

Start: 1350145

End: 1351113

Strand: Direct

Name: glcK [H]

Synonym: Lm4b_01347

Alternate gene names: 226223940

Gene position: 1350145-1351113 (Clockwise)

Preceding gene: 226223939

Following gene: 226223941

Centisome position: 46.35

GC content: 37.56

Gene sequence:

>969_bases
ATGAACAAAAAATTAATTGGTGTAGATTTAGGCGGGACAACAGCAAAATTAGCTATTTTAACAAAAGAAGGCGACATTGA
AGAAAAATGGACAATTGATACAAATATTGAAGAAAAGGGCGCCCACATTGTTAAAAACATTGGGGATTCTATCAATCAAA
AATTAACGGACTTACAACTGGATAATGATATTTTTTATGGTATTGGTATGGGAACTCCAGGTACTGTAAATTATGAAACA
GGTACTGTAAAAGGTGCGTACAACTTAGGCTGGGCAGATGAACAAAATGTTAGTCAAGATTTAGAAAATATTACTGGTTT
AAAAATCATATTAGATAATGATGCTAATGTTGCCGCTCTTGGTGAACGCTGGAAAGGCGCAGGCGAAGGTGGGGCTAATG
TCGTTTTCGTAACACTTGGAACAGGCGTTGGCGGCGGAATTTTCGCAGAAGGCAAAATTTTACATGGTATTCGCGGAGCA
GCTGGTGAAATTGGGCATGTAACAGTAGTTCCTGAGAATGGTTATGATTGTACCTGTGGCAAAAAAGGCTGTTTAGAAAC
TGTCGCATCAGCAACAGGAATCGTTCGAGTAGCGAAAGATTTAGCGAAAGAGTATACTGGTAAATCCGCACTTAAAGATG
CAATAAATAACGATGAAACAATTACTTCTAAATTGATTTTTGAACTAGGAGCAGAAGATGATGCTTTAGCAAATGAAACA
ATTGATAAAATTTCTTTCTATTTGGCTTTAGCGCTCAGTCATATTGGAAACATGTTAAATCCAGAGAAGATTATTATTGG
TGGTGGCGTTTCAGCAGCAGGCGATCAATTATTAACACCGGTTAAAACTTATTTTGAGACAATGGTTTTCCCAGCTGTTA
AAGAATCCACTAAATTATCTATTGCGACAAAAGGGAATGACGCAGGGATAATTGGAGCTGCATGGTTAGCGCTACCAAGT
GAAGATTAA

Upstream 100 bases:

>100_bases
AACTTTTGCTAGAGCTAGAAGTATATTGAAACAAGAATTAATTAAAGAACAACGAAAAAATAGTAGTTTAAATTAAATTG
ATTATAAGGAGAACAGCAGA

Downstream 100 bases:

>100_bases
TATTAATATTAATTTGTATAAGCTACAATAACACTCCATTATTGTAGCTTGTTTTATAAAGCTAATCTTTCTATAACGCA
TTGTTTTAGCTTCCTTTGAA

Product: glucose kinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MNKKLIGVDLGGTTAKLAILTKEGDIEEKWTIDTNIEEKGAHIVKNIGDSINQKLTDLQLDNDIFYGIGMGTPGTVNYET
GTVKGAYNLGWADEQNVSQDLENITGLKIILDNDANVAALGERWKGAGEGGANVVFVTLGTGVGGGIFAEGKILHGIRGA
AGEIGHVTVVPENGYDCTCGKKGCLETVASATGIVRVAKDLAKEYTGKSALKDAINNDETITSKLIFELGAEDDALANET
IDKISFYLALALSHIGNMLNPEKIIIGGGVSAAGDQLLTPVKTYFETMVFPAVKESTKLSIATKGNDAGIIGAAWLALPS
ED

Sequences:

>Translated_322_residues
MNKKLIGVDLGGTTAKLAILTKEGDIEEKWTIDTNIEEKGAHIVKNIGDSINQKLTDLQLDNDIFYGIGMGTPGTVNYET
GTVKGAYNLGWADEQNVSQDLENITGLKIILDNDANVAALGERWKGAGEGGANVVFVTLGTGVGGGIFAEGKILHGIRGA
AGEIGHVTVVPENGYDCTCGKKGCLETVASATGIVRVAKDLAKEYTGKSALKDAINNDETITSKLIFELGAEDDALANET
IDKISFYLALALSHIGNMLNPEKIIIGGGVSAAGDQLLTPVKTYFETMVFPAVKESTKLSIATKGNDAGIIGAAWLALPS
ED
>Mature_322_residues
MNKKLIGVDLGGTTAKLAILTKEGDIEEKWTIDTNIEEKGAHIVKNIGDSINQKLTDLQLDNDIFYGIGMGTPGTVNYET
GTVKGAYNLGWADEQNVSQDLENITGLKIILDNDANVAALGERWKGAGEGGANVVFVTLGTGVGGGIFAEGKILHGIRGA
AGEIGHVTVVPENGYDCTCGKKGCLETVASATGIVRVAKDLAKEYTGKSALKDAINNDETITSKLIFELGAEDDALANET
IDKISFYLALALSHIGNMLNPEKIIIGGGVSAAGDQLLTPVKTYFETMVFPAVKESTKLSIATKGNDAGIIGAAWLALPS
ED

Specific function: Unknown

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=274, Percent_Identity=31.021897810219, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI298566315, Length=274, Percent_Identity=31.021897810219, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI190014632, Length=274, Percent_Identity=31.021897810219, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI4885285, Length=274, Percent_Identity=31.021897810219, Blast_Score=94, Evalue=1e-19,
Organism=Escherichia coli, GI87081733, Length=331, Percent_Identity=32.3262839879154, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1786891, Length=300, Percent_Identity=27.3333333333333, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787878, Length=274, Percent_Identity=26.6423357664234, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787363, Length=325, Percent_Identity=27.6923076923077, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082127, Length=211, Percent_Identity=25.5924170616114, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790522, Length=322, Percent_Identity=25.4658385093168, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082230, Length=280, Percent_Identity=28.2142857142857, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33743; Mature: 33743

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKLIGVDLGGTTAKLAILTKEGDIEEKWTIDTNIEEKGAHIVKNIGDSINQKLTDLQL
CCCEEEEEECCCCEEEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEE
DNDIFYGIGMGTPGTVNYETGTVKGAYNLGWADEQNVSQDLENITGLKIILDNDANVAAL
CCCEEEEECCCCCCEEEECCCEEECCEECCCCCCCHHHHHHHHCCCEEEEEECCCCEEEH
GERWKGAGEGGANVVFVTLGTGVGGGIFAEGKILHGIRGAAGEIGHVTVVPENGYDCTCG
HHHCCCCCCCCCEEEEEEECCCCCCCEEECCEEEECCCCCCCCCCEEEEEECCCCCCCCC
KKGCLETVASATGIVRVAKDLAKEYTGKSALKDAINNDETITSKLIFELGAEDDALANET
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHH
IDKISFYLALALSHIGNMLNPEKIIIGGGVSAAGDQLLTPVKTYFETMVFPAVKESTKLS
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEE
IATKGNDAGIIGAAWLALPSED
EEECCCCCCEEEEEEEECCCCC
>Mature Secondary Structure
MNKKLIGVDLGGTTAKLAILTKEGDIEEKWTIDTNIEEKGAHIVKNIGDSINQKLTDLQL
CCCEEEEEECCCCEEEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEE
DNDIFYGIGMGTPGTVNYETGTVKGAYNLGWADEQNVSQDLENITGLKIILDNDANVAAL
CCCEEEEECCCCCCEEEECCCEEECCEECCCCCCCHHHHHHHHCCCEEEEEECCCCEEEH
GERWKGAGEGGANVVFVTLGTGVGGGIFAEGKILHGIRGAAGEIGHVTVVPENGYDCTCG
HHHCCCCCCCCCEEEEEEECCCCCCCEEECCEEEECCCCCCCCCCEEEEEECCCCCCCCC
KKGCLETVASATGIVRVAKDLAKEYTGKSALKDAINNDETITSKLIFELGAEDDALANET
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHH
IDKISFYLALALSHIGNMLNPEKIIIGGGVSAAGDQLLTPVKTYFETMVFPAVKESTKLS
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEE
IATKGNDAGIIGAAWLALPSED
EEECCCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]