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The map label for this gene is treB [H]

Identifier: 226223858

GI number: 226223858

Start: 1266026

End: 1267510

Strand: Reverse

Name: treB [H]

Synonym: Lm4b_01265

Alternate gene names: 226223858

Gene position: 1267510-1266026 (Counterclockwise)

Preceding gene: 226223860

Following gene: 226223857

Centisome position: 43.52

GC content: 39.39

Gene sequence:

>1485_bases
ATGGTTGACTATACAAAAGATGCAAGCGCTCTTTTAGAGTTAATTGGTGGCAAAGAAAATATATCATCTGTCACACATTG
TGCTACGAGAATGCGTTTTGTTTTGCAAAATCCAGATAATGCCGATGTTGAAGCCATCGAAGACATTCCAGCAGTAAAAG
GGACATTTACACAAGCTGGTCAATTTCAAGTAATTATAGGTAATGATGTAGCTATTTTTTATAATGAATTTTCAAAAATT
AGTGGTGTGGAAGGTGTCAATAAAGAAGATGCCAAAGTAGATGCGAAGAAAAATATGAGTATTCTTCAGCGTTTACTTGC
TGGTTTAGCTGAAATATTCACTCCATTAATTCCAGCAATTGTTGTTGGGGGTCTTATTCTCGGTTTCCGTAACGTAATTG
GAGATATTAAGTTTTTAGAAGACGGCACGAAAACGATTGTGGATGTTTATCCATTTTGGGCTGGTGTTTATAGTTTCTTA
TGGCTTATCGGTGAGGCTGTATTCCACTTCCTACCAGTTGGAATTACATGGTCCATCGCGAAAAAAATGGGAACCACACA
AATTCTTGGGATTGTCCTTGGCTTAACGCTTGTTTCCCCGCAATTACTAAATGCTTATAGCGTTGTTGAAACAAAAGCAG
GCGATATTCCAGTTTGGGACTTTGGCTTTGCTCAAGTACAGATGATTGGGTATCAAGCGCAAGTTATTCCTGCCATTATG
GCCGGATTCTTACTAGCCTATCTCGAAATTTGGTTGCGTAAATTTATTCCAAATGCCATTTCGATGATTTTCGTTCCATT
CTTTGCTCTCGTACCTACTGTTCTTGCAGCTCATGTTATTCTTGGACCAATTGGTTGGAAAATTGGCGACGCGATTTCGA
ACGTCGTTTATGCTGGCTTGACTGGTGGACTAAGTTGGTTATTCGCCGCACTATTTGGCTTCCTATATGCCCCGCTCGTT
GTCACGGGACTGCATCATATGACCAACGCCATCGACTTACAATTAATGAGTCAATTTGGTGGAACGAATCTCTGGCCGAT
GATTGCACTTTCTAACATCGCCCAAGGGTCCGCTGTTCTAGCAATTATTTTCTTACATCGTGGCAATGAAAAAGAAGAAC
AAGTTTCAATTCCAGCAACTATTTCTTGTTACCTTGGTGTTACGGAACCTGCGATGTTCGGGATTAATTTAAAATACTTA
TATCCATTTGTAGCTGCCATGATAGGTTCGGCAATTGCGGCTGTGGTTTCTGTATCTAGTGGTGTTATGGCTAACTCAAT
TGGTGTCGGAGGACTACCTGGAATCTTGTCCATTAACCCTAAATATTACGCCGTTTTTGCAGTATGTATGTTAATAACGA
TTGTTGTTCCTTTCATTCTAACTGTATTATTCCGCAAATATAATATTTTAAACAAAGTAGATACTGCACCAATTCGTACG
TTTGGTAAAAAGGAGTATCGTGAATCTGCAAAAACAACCAACTAA

Upstream 100 bases:

>100_bases
TTTTATTTTAGCACAAATAAAGTGGTTGCGCTTTCAAATTATCTATAGTATAGTAATGGCGAACAACTTGTATATACAAG
TTAAAAAAGGAGGAAGTTTT

Downstream 100 bases:

>100_bases
AAAGTGAGGCTTCCCTTTATGACAAAGTTTGCTCAAAAAACAATTTATCAAGTGTATCCGAAATCCTTTTATGATACGAC
TGGCGATGGTACTGGGGATA

Product: PTS system trehalose specific enzyme IIBC

Products: NA

Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MVDYTKDASALLELIGGKENISSVTHCATRMRFVLQNPDNADVEAIEDIPAVKGTFTQAGQFQVIIGNDVAIFYNEFSKI
SGVEGVNKEDAKVDAKKNMSILQRLLAGLAEIFTPLIPAIVVGGLILGFRNVIGDIKFLEDGTKTIVDVYPFWAGVYSFL
WLIGEAVFHFLPVGITWSIAKKMGTTQILGIVLGLTLVSPQLLNAYSVVETKAGDIPVWDFGFAQVQMIGYQAQVIPAIM
AGFLLAYLEIWLRKFIPNAISMIFVPFFALVPTVLAAHVILGPIGWKIGDAISNVVYAGLTGGLSWLFAALFGFLYAPLV
VTGLHHMTNAIDLQLMSQFGGTNLWPMIALSNIAQGSAVLAIIFLHRGNEKEEQVSIPATISCYLGVTEPAMFGINLKYL
YPFVAAMIGSAIAAVVSVSSGVMANSIGVGGLPGILSINPKYYAVFAVCMLITIVVPFILTVLFRKYNILNKVDTAPIRT
FGKKEYRESAKTTN

Sequences:

>Translated_494_residues
MVDYTKDASALLELIGGKENISSVTHCATRMRFVLQNPDNADVEAIEDIPAVKGTFTQAGQFQVIIGNDVAIFYNEFSKI
SGVEGVNKEDAKVDAKKNMSILQRLLAGLAEIFTPLIPAIVVGGLILGFRNVIGDIKFLEDGTKTIVDVYPFWAGVYSFL
WLIGEAVFHFLPVGITWSIAKKMGTTQILGIVLGLTLVSPQLLNAYSVVETKAGDIPVWDFGFAQVQMIGYQAQVIPAIM
AGFLLAYLEIWLRKFIPNAISMIFVPFFALVPTVLAAHVILGPIGWKIGDAISNVVYAGLTGGLSWLFAALFGFLYAPLV
VTGLHHMTNAIDLQLMSQFGGTNLWPMIALSNIAQGSAVLAIIFLHRGNEKEEQVSIPATISCYLGVTEPAMFGINLKYL
YPFVAAMIGSAIAAVVSVSSGVMANSIGVGGLPGILSINPKYYAVFAVCMLITIVVPFILTVLFRKYNILNKVDTAPIRT
FGKKEYRESAKTTN
>Mature_494_residues
MVDYTKDASALLELIGGKENISSVTHCATRMRFVLQNPDNADVEAIEDIPAVKGTFTQAGQFQVIIGNDVAIFYNEFSKI
SGVEGVNKEDAKVDAKKNMSILQRLLAGLAEIFTPLIPAIVVGGLILGFRNVIGDIKFLEDGTKTIVDVYPFWAGVYSFL
WLIGEAVFHFLPVGITWSIAKKMGTTQILGIVLGLTLVSPQLLNAYSVVETKAGDIPVWDFGFAQVQMIGYQAQVIPAIM
AGFLLAYLEIWLRKFIPNAISMIFVPFFALVPTVLAAHVILGPIGWKIGDAISNVVYAGLTGGLSWLFAALFGFLYAPLV
VTGLHHMTNAIDLQLMSQFGGTNLWPMIALSNIAQGSAVLAIIFLHRGNEKEEQVSIPATISCYLGVTEPAMFGINLKYL
YPFVAAMIGSAIAAVVSVSSGVMANSIGVGGLPGILSINPKYYAVFAVCMLITIVVPFILTVLFRKYNILNKVDTAPIRT
FGKKEYRESAKTTN

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=466, Percent_Identity=52.5751072961373, Blast_Score=462, Evalue=1e-131,
Organism=Escherichia coli, GI48994906, Length=472, Percent_Identity=29.4491525423729, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1790159, Length=419, Percent_Identity=27.6849642004773, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1788769, Length=500, Percent_Identity=25.2, Blast_Score=113, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011296 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 53464; Mature: 53464

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDYTKDASALLELIGGKENISSVTHCATRMRFVLQNPDNADVEAIEDIPAVKGTFTQAG
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCC
QFQVIIGNDVAIFYNEFSKISGVEGVNKEDAKVDAKKNMSILQRLLAGLAEIFTPLIPAI
CEEEEECCCEEEEEHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHH
VVGGLILGFRNVIGDIKFLEDGTKTIVDVYPFWAGVYSFLWLIGEAVFHFLPVGITWSIA
HHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
KKMGTTQILGIVLGLTLVSPQLLNAYSVVETKAGDIPVWDFGFAQVQMIGYQAQVIPAIM
HHCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHH
AGFLLAYLEIWLRKFIPNAISMIFVPFFALVPTVLAAHVILGPIGWKIGDAISNVVYAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TGGLSWLFAALFGFLYAPLVVTGLHHMTNAIDLQLMSQFGGTNLWPMIALSNIAQGSAVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHE
AIIFLHRGNEKEEQVSIPATISCYLGVTEPAMFGINLKYLYPFVAAMIGSAIAAVVSVSS
EEEEEECCCCCHHHCCCCEEEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
GVMANSIGVGGLPGILSINPKYYAVFAVCMLITIVVPFILTVLFRKYNILNKVDTAPIRT
CCHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
FGKKEYRESAKTTN
HHHHHHHHHCCCCC
>Mature Secondary Structure
MVDYTKDASALLELIGGKENISSVTHCATRMRFVLQNPDNADVEAIEDIPAVKGTFTQAG
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCC
QFQVIIGNDVAIFYNEFSKISGVEGVNKEDAKVDAKKNMSILQRLLAGLAEIFTPLIPAI
CEEEEECCCEEEEEHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHH
VVGGLILGFRNVIGDIKFLEDGTKTIVDVYPFWAGVYSFLWLIGEAVFHFLPVGITWSIA
HHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
KKMGTTQILGIVLGLTLVSPQLLNAYSVVETKAGDIPVWDFGFAQVQMIGYQAQVIPAIM
HHCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHH
AGFLLAYLEIWLRKFIPNAISMIFVPFFALVPTVLAAHVILGPIGWKIGDAISNVVYAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TGGLSWLFAALFGFLYAPLVVTGLHHMTNAIDLQLMSQFGGTNLWPMIALSNIAQGSAVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHE
AIIFLHRGNEKEEQVSIPATISCYLGVTEPAMFGINLKYLYPFVAAMIGSAIAAVVSVSS
EEEEEECCCCCHHHCCCCEEEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
GVMANSIGVGGLPGILSINPKYYAVFAVCMLITIVVPFILTVLFRKYNILNKVDTAPIRT
CCHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
FGKKEYRESAKTTN
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7608078; 7610040; 9278503 [H]