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The map label for this gene is treA [H]

Identifier: 226223857

GI number: 226223857

Start: 1264361

End: 1266007

Strand: Reverse

Name: treA [H]

Synonym: Lm4b_01264

Alternate gene names: 226223857

Gene position: 1266007-1264361 (Counterclockwise)

Preceding gene: 226223858

Following gene: 226223855

Centisome position: 43.47

GC content: 39.04

Gene sequence:

>1647_bases
ATGACAAAGTTTGCTCAAAAAACAATTTATCAAGTGTATCCGAAATCCTTTTATGATACGACTGGCGATGGTACTGGGGA
TATTCCCGGTATCACTGCCAAGCTTGATTATTTACAAAAACTCGGAATTGAGATGATTTGGCTGAATCCATTTTATCCTT
CTCCGCAAAATGATAACGGCTATGATATCGCTGACTATACCGCGGTTGATCCTTTATTTGGTACGATGGACGATGTGACA
ACGCTTATCAAGGAAGCGAAAAAAAGAAATATTGGTATTATGATTGACTTAGTATTGAATCATACTTCAACAGAGCATCC
TTGGTTTAAAAAAGCGCTTGCTGGTGATCCATTCTATCGTGATTTCTACTATTTCCGCCCAGCAAAAGCCGATGGTTCCC
CTCCAACAAATTGGGTTTCCAAATTCGGTGGTAATGCTTGGGAAAAATTGCCTGACTCCTCTGAGTACTATTTGCATTTA
TACGATGTTACGCAAGCTGATTTAGACTGGGCCAATCCGAATGTACGCGAGGCACTCTTTGATGTCGTGAATTTTTGGAT
TGATAAAGGCGTGGAAGGTTTTCGTTTAGATGTATTAAATGTGATTGCCAAACCTAAGTTTTTAGAAGATGATTTTGAAG
GCGACGGCCGCCGTTTTTATACAGATGGACCAGGAATACATGCTTACTTAAAAGAACTACATGAACGAACTTTTGGCGAC
AAGCCAATTATAACGGTTGGAGAAATGTCCTCTACAGATATTGACAACTGCATTCGTTATAGTAATCCAGACGAAAAAGA
ATTATCGATGGTTTTTCATTTCCATCATTTGAAGGTAGACTATCCTGATGGAGAAAAATGGCGTTTAGCGGATGTGAATT
TCGAGAACTTAAAATCTATTTTCCATACGTGGCAAGTCGCGATGTCAGAAGAAAATGGATGGGATGCGCTTTTCTGGAAC
AACCATGACCAACCTCGAGCACTTGGTCGCTTTGCTTCCGACAAACCGGAACATTATTATCATTCGGCAACCCTCCTTGG
CGCAACGATTCACTTTATGCGCGGGACACCGTTTGTTTATATGGGGGAAGAAATCGGGATGATGAATCCAAAATTTCCTA
CGATTGATGATTATGTGGATGTGGAAACGCTCAACCATTTTGATATTTTACAAAAAAACGGACTTAGTGAGCAAGAAGTT
ATGGCGATTATCAAAGAGCGTTCGCGAGATAATAGTCGGACACCTATGCAATGGGATGATTCGCAAAATGCTGGCTTTAC
AACTGGTACTCCATGGCTAAAAGTAGCGGATAATGCAAGTGAAATAAATGTTCAAGCAGCCTTATCTAATAAAACGAGCA
TTTTCTATTTTTACCAAAAGCTTATTGCATTACGGAAAGAATACCCTGTCATTCAGACGGGTGATTATACGCCATATTGG
ACGGATGAAGATTTGATTATAGCCTATAAGCGTTCAAATGAAATTACTTCGCTTCTTTCCATTCACCATTTTGGCTCGAC
TACGAAAAAAATTCAACTACCAAATGAGTTTTTAAATGCTAAAGTACTTCTTTCTAATTATGAACGTCAAACAATCAGTT
CTGAGCTGGAATTAGCACCTTATGAAACATTAACTTTAATTCGATAA

Upstream 100 bases:

>100_bases
TATTTTAAACAAAGTAGATACTGCACCAATTCGTACGTTTGGTAAAAAGGAGTATCGTGAATCTGCAAAAACAACCAACT
AAAAAGTGAGGCTTCCCTTT

Downstream 100 bases:

>100_bases
AAAAAGCCTGAGAAACAATTCTCAGGCTTTTTAGCGTCTTCTTGCAAAATCTATAAAACGGAATTTATCCAGTCGGTGAC
GCGATTCTGTGTATTGAAAA

Product: alpha,alpha-phosphotrehalase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 548; Mature: 547

Protein sequence:

>548_residues
MTKFAQKTIYQVYPKSFYDTTGDGTGDIPGITAKLDYLQKLGIEMIWLNPFYPSPQNDNGYDIADYTAVDPLFGTMDDVT
TLIKEAKKRNIGIMIDLVLNHTSTEHPWFKKALAGDPFYRDFYYFRPAKADGSPPTNWVSKFGGNAWEKLPDSSEYYLHL
YDVTQADLDWANPNVREALFDVVNFWIDKGVEGFRLDVLNVIAKPKFLEDDFEGDGRRFYTDGPGIHAYLKELHERTFGD
KPIITVGEMSSTDIDNCIRYSNPDEKELSMVFHFHHLKVDYPDGEKWRLADVNFENLKSIFHTWQVAMSEENGWDALFWN
NHDQPRALGRFASDKPEHYYHSATLLGATIHFMRGTPFVYMGEEIGMMNPKFPTIDDYVDVETLNHFDILQKNGLSEQEV
MAIIKERSRDNSRTPMQWDDSQNAGFTTGTPWLKVADNASEINVQAALSNKTSIFYFYQKLIALRKEYPVIQTGDYTPYW
TDEDLIIAYKRSNEITSLLSIHHFGSTTKKIQLPNEFLNAKVLLSNYERQTISSELELAPYETLTLIR

Sequences:

>Translated_548_residues
MTKFAQKTIYQVYPKSFYDTTGDGTGDIPGITAKLDYLQKLGIEMIWLNPFYPSPQNDNGYDIADYTAVDPLFGTMDDVT
TLIKEAKKRNIGIMIDLVLNHTSTEHPWFKKALAGDPFYRDFYYFRPAKADGSPPTNWVSKFGGNAWEKLPDSSEYYLHL
YDVTQADLDWANPNVREALFDVVNFWIDKGVEGFRLDVLNVIAKPKFLEDDFEGDGRRFYTDGPGIHAYLKELHERTFGD
KPIITVGEMSSTDIDNCIRYSNPDEKELSMVFHFHHLKVDYPDGEKWRLADVNFENLKSIFHTWQVAMSEENGWDALFWN
NHDQPRALGRFASDKPEHYYHSATLLGATIHFMRGTPFVYMGEEIGMMNPKFPTIDDYVDVETLNHFDILQKNGLSEQEV
MAIIKERSRDNSRTPMQWDDSQNAGFTTGTPWLKVADNASEINVQAALSNKTSIFYFYQKLIALRKEYPVIQTGDYTPYW
TDEDLIIAYKRSNEITSLLSIHHFGSTTKKIQLPNEFLNAKVLLSNYERQTISSELELAPYETLTLIR
>Mature_547_residues
TKFAQKTIYQVYPKSFYDTTGDGTGDIPGITAKLDYLQKLGIEMIWLNPFYPSPQNDNGYDIADYTAVDPLFGTMDDVTT
LIKEAKKRNIGIMIDLVLNHTSTEHPWFKKALAGDPFYRDFYYFRPAKADGSPPTNWVSKFGGNAWEKLPDSSEYYLHLY
DVTQADLDWANPNVREALFDVVNFWIDKGVEGFRLDVLNVIAKPKFLEDDFEGDGRRFYTDGPGIHAYLKELHERTFGDK
PIITVGEMSSTDIDNCIRYSNPDEKELSMVFHFHHLKVDYPDGEKWRLADVNFENLKSIFHTWQVAMSEENGWDALFWNN
HDQPRALGRFASDKPEHYYHSATLLGATIHFMRGTPFVYMGEEIGMMNPKFPTIDDYVDVETLNHFDILQKNGLSEQEVM
AIIKERSRDNSRTPMQWDDSQNAGFTTGTPWLKVADNASEINVQAALSNKTSIFYFYQKLIALRKEYPVIQTGDYTPYWT
DEDLIIAYKRSNEITSLLSIHHFGSTTKKIQLPNEFLNAKVLLSNYERQTISSELELAPYETLTLIR

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=525, Percent_Identity=26.4761904761905, Blast_Score=197, Evalue=1e-50,
Organism=Escherichia coli, GI1790687, Length=538, Percent_Identity=49.4423791821561, Blast_Score=551, Evalue=1e-158,
Organism=Escherichia coli, GI1786604, Length=189, Percent_Identity=26.984126984127, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081873, Length=159, Percent_Identity=28.3018867924528, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI25147709, Length=494, Percent_Identity=25.5060728744939, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI32565753, Length=201, Percent_Identity=28.8557213930348, Blast_Score=91, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322245, Length=567, Percent_Identity=33.8624338624339, Blast_Score=332, Evalue=1e-91,
Organism=Saccharomyces cerevisiae, GI6321726, Length=581, Percent_Identity=33.9070567986231, Blast_Score=317, Evalue=2e-87,
Organism=Saccharomyces cerevisiae, GI6321731, Length=568, Percent_Identity=35.5633802816901, Blast_Score=316, Evalue=5e-87,
Organism=Saccharomyces cerevisiae, GI6319776, Length=568, Percent_Identity=35.387323943662, Blast_Score=315, Evalue=2e-86,
Organism=Saccharomyces cerevisiae, GI6324416, Length=581, Percent_Identity=34.2512908777969, Blast_Score=311, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6322241, Length=581, Percent_Identity=34.4234079173838, Blast_Score=310, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6322021, Length=581, Percent_Identity=34.4234079173838, Blast_Score=310, Evalue=3e-85,
Organism=Drosophila melanogaster, GI221330053, Length=585, Percent_Identity=31.7948717948718, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24586593, Length=580, Percent_Identity=31.7241379310345, Blast_Score=254, Evalue=7e-68,
Organism=Drosophila melanogaster, GI24586591, Length=578, Percent_Identity=30.9688581314879, Blast_Score=251, Evalue=6e-67,
Organism=Drosophila melanogaster, GI24586599, Length=537, Percent_Identity=30.7262569832402, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24586589, Length=502, Percent_Identity=33.8645418326693, Blast_Score=245, Evalue=6e-65,
Organism=Drosophila melanogaster, GI24583745, Length=586, Percent_Identity=29.8634812286689, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI45549022, Length=580, Percent_Identity=31.2068965517241, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI24586597, Length=539, Percent_Identity=28.9424860853432, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24583749, Length=542, Percent_Identity=31.7343173431734, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24583747, Length=542, Percent_Identity=31.7343173431734, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24586587, Length=581, Percent_Identity=29.4320137693632, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI281360393, Length=529, Percent_Identity=29.8676748582231, Blast_Score=198, Evalue=8e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 63191; Mature: 63059

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKFAQKTIYQVYPKSFYDTTGDGTGDIPGITAKLDYLQKLGIEMIWLNPFYPSPQNDNG
CCCHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCC
YDIADYTAVDPLFGTMDDVTTLIKEAKKRNIGIMIDLVLNHTSTEHPWFKKALAGDPFYR
CCCCCCCCCCCHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHCCCCCHH
DFYYFRPAKADGSPPTNWVSKFGGNAWEKLPDSSEYYLHLYDVTQADLDWANPNVREALF
CEEEEECCCCCCCCCHHHHHHHCCCHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHHHH
DVVNFWIDKGVEGFRLDVLNVIAKPKFLEDDFEGDGRRFYTDGPGIHAYLKELHERTFGD
HHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCC
KPIITVGEMSSTDIDNCIRYSNPDEKELSMVFHFHHLKVDYPDGEKWRLADVNFENLKSI
CCEEEECCCCCCCHHHHHHCCCCCHHHHEEEEEEEEEEEECCCCCEEEEECCCHHHHHHH
FHTWQVAMSEENGWDALFWNNHDQPRALGRFASDKPEHYYHSATLLGATIHFMRGTPFVY
HHHHHHEECCCCCCEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
MGEEIGMMNPKFPTIDDYVDVETLNHFDILQKNGLSEQEVMAIIKERSRDNSRTPMQWDD
ECCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCC
SQNAGFTTGTPWLKVADNASEINVQAALSNKTSIFYFYQKLIALRKEYPVIQTGDYTPYW
CCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEECCCCCCCC
TDEDLIIAYKRSNEITSLLSIHHFGSTTKKIQLPNEFLNAKVLLSNYERQTISSELELAP
CCCCEEEEEECCCCHHHHHHHHHCCCCCEEEECCHHHHCHHHEECCCHHHHHCCCCCCCC
YETLTLIR
CCEEEECC
>Mature Secondary Structure 
TKFAQKTIYQVYPKSFYDTTGDGTGDIPGITAKLDYLQKLGIEMIWLNPFYPSPQNDNG
CCHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCC
YDIADYTAVDPLFGTMDDVTTLIKEAKKRNIGIMIDLVLNHTSTEHPWFKKALAGDPFYR
CCCCCCCCCCCHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHCCCCCHH
DFYYFRPAKADGSPPTNWVSKFGGNAWEKLPDSSEYYLHLYDVTQADLDWANPNVREALF
CEEEEECCCCCCCCCHHHHHHHCCCHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHHHH
DVVNFWIDKGVEGFRLDVLNVIAKPKFLEDDFEGDGRRFYTDGPGIHAYLKELHERTFGD
HHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCC
KPIITVGEMSSTDIDNCIRYSNPDEKELSMVFHFHHLKVDYPDGEKWRLADVNFENLKSI
CCEEEECCCCCCCHHHHHHCCCCCHHHHEEEEEEEEEEEECCCCCEEEEECCCHHHHHHH
FHTWQVAMSEENGWDALFWNNHDQPRALGRFASDKPEHYYHSATLLGATIHFMRGTPFVY
HHHHHHEECCCCCCEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
MGEEIGMMNPKFPTIDDYVDVETLNHFDILQKNGLSEQEVMAIIKERSRDNSRTPMQWDD
ECCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCC
SQNAGFTTGTPWLKVADNASEINVQAALSNKTSIFYFYQKLIALRKEYPVIQTGDYTPYW
CCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEECCCCCCCC
TDEDLIIAYKRSNEITSLLSIHHFGSTTKKIQLPNEFLNAKVLLSNYERQTISSELELAP
CCCCEEEEEECCCCHHHHHHHHHCCCCCEEEECCHHHHCHHHEECCCHHHHHCCCCCCCC
YETLTLIR
CCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7651129; 8969503; 9384377; 7751281 [H]