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The map label for this gene is ywoG [H]

Identifier: 226223853

GI number: 226223853

Start: 1259781

End: 1260986

Strand: Reverse

Name: ywoG [H]

Synonym: Lm4b_01258

Alternate gene names: 226223853

Gene position: 1260986-1259781 (Counterclockwise)

Preceding gene: 226223855

Following gene: 226223852

Centisome position: 43.29

GC content: 37.4

Gene sequence:

>1206_bases
ATGAAAGAAAAATTATTTAACAAGGGTTTTGTCTTAATAACATTGATTAACTTTGTCGTTTATCTCGTTTATTATTTGCT
AATGGTTATTATTGCCGTTATTGCTCAAGAAGAGTTGAACGCGTCTCTTGGTGAAGCCGGATTTGCGTCTGGGATTTATA
TTATCGGGACGCTCCTCGCACGACTTTACATGGGGAAAAAGCTGGAACTATTTGGTCGTAAGCGGGTTTTAAGATTTGGG
ATTTTATTTTTCTTAGTAACGACGATGGCTTACTTATACATGCCAACGATTGCCATTATGTTTATTATTCGTTTTTTAAA
TGGATTCGCATACGGAACAACTTCAACTGCTACCAATGCGATTGTCACAGCTTATATTCCTAATTCTAGAAACGGAGAAG
GGATTAATTATTATGGCCTCAGCACAAGTCTCGCAGCTGCGATTGGACCGTTCATCGGAATGATTTTACTTAGCAAAACG
AGCTTTTATACGATTATTATTTTCTCCACGGTTATTGTCTTATTAACTGCGCTACTTTGCTTCTATTTACCCGTGAAAAA
TATTGTTTTAACAACCGAACACCGGAAGGCCTTACAAACTTGGACCGTCAAAAGTTTTATTGAATATAAAGTTATTCCAA
TAACATTTATTGCCTTCTTAATGGGGATTTCTTATTCCAGTGTGCTTACATTCCTTGCTTCCTATGCTAGAGAAATTAAT
TTAGTGAGTGCTGGAACGTTCTTCTTTGTTGTCTATGCATTAGTTATTACTCTAACTCGCCCAATGTCTGGAAAACTTTT
CGATGCAAAAGGCGAAAAATATGTGATGTATCCAAGTTATCTCTTTTTAGCAGTTGGATTAGTGGTCCTTAGTACAGCAA
CATCAAGTCTCGTGCTACTTATTTCAGGCGGACTCATCGGCTTAGGTTATGGAACGTTTATGTCGAATGGCCAAGCTGTC
TGTTTAAAAGTATGTGAACCTCACCGTATTGGGATTGGCCTATCTACCTACTTTATCGGGCTTGATTTAGGACTTGGTAT
TGGGCCTTATATTATGGGTGAAATTCATCATGTGCTTTCATTCCAAGGTATTTACATTATTGCCGGTGCTATCGCATTTA
TTTGCGTATTCATCTATATGTTTTTATCCAGAAAAAAAGTGTCTAGTGGTGCACAGGAACAACTAAAAGGGAGTGAAGAA
GTATGA

Upstream 100 bases:

>100_bases
ATAATTACCAAATTAAAAAGTATCCTCTCCGAATATCCCCTATAATACTCCTTGTCGCTGAGATAAATTACAAATTATAG
GTAGGAAGGGATTTTATTCT

Downstream 100 bases:

>100_bases
ATAAATTATTACTCATTACAGCAGCGGGTTATATCGTAGGAGTTAGAAGTATAGAAAAGGAGAACAACCAATCTATTCTA
CTAAACGATGTCTACATTAA

Product: antibiotic resistance protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MKEKLFNKGFVLITLINFVVYLVYYLLMVIIAVIAQEELNASLGEAGFASGIYIIGTLLARLYMGKKLELFGRKRVLRFG
ILFFLVTTMAYLYMPTIAIMFIIRFLNGFAYGTTSTATNAIVTAYIPNSRNGEGINYYGLSTSLAAAIGPFIGMILLSKT
SFYTIIIFSTVIVLLTALLCFYLPVKNIVLTTEHRKALQTWTVKSFIEYKVIPITFIAFLMGISYSSVLTFLASYAREIN
LVSAGTFFFVVYALVITLTRPMSGKLFDAKGEKYVMYPSYLFLAVGLVVLSTATSSLVLLISGGLIGLGYGTFMSNGQAV
CLKVCEPHRIGIGLSTYFIGLDLGLGIGPYIMGEIHHVLSFQGIYIIAGAIAFICVFIYMFLSRKKVSSGAQEQLKGSEE
V

Sequences:

>Translated_401_residues
MKEKLFNKGFVLITLINFVVYLVYYLLMVIIAVIAQEELNASLGEAGFASGIYIIGTLLARLYMGKKLELFGRKRVLRFG
ILFFLVTTMAYLYMPTIAIMFIIRFLNGFAYGTTSTATNAIVTAYIPNSRNGEGINYYGLSTSLAAAIGPFIGMILLSKT
SFYTIIIFSTVIVLLTALLCFYLPVKNIVLTTEHRKALQTWTVKSFIEYKVIPITFIAFLMGISYSSVLTFLASYAREIN
LVSAGTFFFVVYALVITLTRPMSGKLFDAKGEKYVMYPSYLFLAVGLVVLSTATSSLVLLISGGLIGLGYGTFMSNGQAV
CLKVCEPHRIGIGLSTYFIGLDLGLGIGPYIMGEIHHVLSFQGIYIIAGAIAFICVFIYMFLSRKKVSSGAQEQLKGSEE
V
>Mature_401_residues
MKEKLFNKGFVLITLINFVVYLVYYLLMVIIAVIAQEELNASLGEAGFASGIYIIGTLLARLYMGKKLELFGRKRVLRFG
ILFFLVTTMAYLYMPTIAIMFIIRFLNGFAYGTTSTATNAIVTAYIPNSRNGEGINYYGLSTSLAAAIGPFIGMILLSKT
SFYTIIIFSTVIVLLTALLCFYLPVKNIVLTTEHRKALQTWTVKSFIEYKVIPITFIAFLMGISYSSVLTFLASYAREIN
LVSAGTFFFVVYALVITLTRPMSGKLFDAKGEKYVMYPSYLFLAVGLVVLSTATSSLVLLISGGLIGLGYGTFMSNGQAV
CLKVCEPHRIGIGLSTYFIGLDLGLGIGPYIMGEIHHVLSFQGIYIIAGAIAFICVFIYMFLSRKKVSSGAQEQLKGSEE
V

Specific function: Involved In Sulfonamide (Sulfathiazole) And Bicyclomycin Resistance. Probable Membrane Translocase. [C]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44131; Mature: 44131

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKLFNKGFVLITLINFVVYLVYYLLMVIIAVIAQEELNASLGEAGFASGIYIIGTLLA
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCHHHHHHHHHH
RLYMGKKLELFGRKRVLRFGILFFLVTTMAYLYMPTIAIMFIIRFLNGFAYGTTSTATNA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
IVTAYIPNSRNGEGINYYGLSTSLAAAIGPFIGMILLSKTSFYTIIIFSTVIVLLTALLC
EEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
FYLPVKNIVLTTEHRKALQTWTVKSFIEYKVIPITFIAFLMGISYSSVLTFLASYAREIN
HHHHHHHEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
LVSAGTFFFVVYALVITLTRPMSGKLFDAKGEKYVMYPSYLFLAVGLVVLSTATSSLVLL
CEEHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHH
ISGGLIGLGYGTFMSNGQAVCLKVCEPHRIGIGLSTYFIGLDLGLGIGPYIMGEIHHVLS
EECCCCEECHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
FQGIYIIAGAIAFICVFIYMFLSRKKVSSGAQEQLKGSEEV
HCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCC
>Mature Secondary Structure
MKEKLFNKGFVLITLINFVVYLVYYLLMVIIAVIAQEELNASLGEAGFASGIYIIGTLLA
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCHHHHHHHHHH
RLYMGKKLELFGRKRVLRFGILFFLVTTMAYLYMPTIAIMFIIRFLNGFAYGTTSTATNA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
IVTAYIPNSRNGEGINYYGLSTSLAAAIGPFIGMILLSKTSFYTIIIFSTVIVLLTALLC
EEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
FYLPVKNIVLTTEHRKALQTWTVKSFIEYKVIPITFIAFLMGISYSSVLTFLASYAREIN
HHHHHHHEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
LVSAGTFFFVVYALVITLTRPMSGKLFDAKGEKYVMYPSYLFLAVGLVVLSTATSSLVLL
CEEHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHH
ISGGLIGLGYGTFMSNGQAVCLKVCEPHRIGIGLSTYFIGLDLGLGIGPYIMGEIHHVLS
EECCCCEECHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
FQGIYIIAGAIAFICVFIYMFLSRKKVSSGAQEQLKGSEEV
HCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]