Click here to switch to the map view.

The map label for this gene is hsdM [C]

Identifier: 226223147

GI number: 226223147

Start: 555658

End: 557247

Strand: Direct

Name: hsdM [C]

Synonym: Lm4b_00544

Alternate gene names: 226223147

Gene position: 555658-557247 (Clockwise)

Preceding gene: 226223146

Following gene: 226223148

Centisome position: 19.08

GC content: 35.03

Gene sequence:

>1590_bases
ATGGCATTATCAACTGAACAAAAAACAAAAATGTGGGCAATGCTCAACCAAACACGCGGTCAAATTGGTTTAACTGCGTA
TAAAGACTATATCTTTGGAATTTTGTTTTATAAATACTTATCTGAAAAAGCAACACATTGGCTAAACGGCGTATTACGCG
GGGAAAATTGGGAGAGTGTTTATTCTCAAGATTCTGTAAAGGCCTTAAATTATATGAAAAAGAATCTTGGATATGCGATT
CAACCAAATGAATTCTTTGTAGACTGGAAAAAAGCAATTGATACGGACCGTTTCAATATTGGGATGATGACAGATACATT
TACGCATTTTAATCAACAAATTGCATTTGAAGCGAAAAATGATTTTGAAGGAATTTTTGATGGTATGCGCTTTGATAGTG
CGGATTTAGGTGCTAATGCACAAGCTAGGGCTAGTGTCATGATTTCTATGATTGAATTGCTATCCTCTCCTGAATTTGAT
TTATCTGGTAGTAATGATACTGTTTCAGATATTTATGAGTATCTAGTTGCACAATTTGCTACTGTCCTAGCATCTGATAT
GGGACAATACTATACACCAAAAGAAATATCTAATGTAATGGCTCGGATTTTAACTTTTGGCCGAGAAGATATGGAAAAAT
TTTCTATCTTTGATCCTACTGTTGGTTCTGGTTCACTTTTACTTACAACCGCTAGTTATATGAAGAACTCAGGTAGACGC
GGGGTGATTAAGTATTATGGTCAAGAAAAAGATGCAACACCTTACCGTTTATCAAGAATGAATTTGATGATGCACGGTAT
TGAATATAATGATATTAATATTAATCATGCGGATACACTTGAAAGCGATTGGCCAGATGGGGTAGTGGATGGAAAAGATA
CTCCTCGAATGTTTGATGCAGTAATGGCGAATCCTCCTTATTCAGCACATTGGAATAATAAAGATCGTGAAGATGACCCA
AGATGGCGGGAATATGGTGTTTCACCTAAGACAAAAGCTGATTATGCCTTTTTATTACACTGTTTGTATCACTTAGAAGA
TAATGGACGCATGGCGATTATTTTACCACATGGTGTATTATTCCGCGGAGCTTCTGAGGGGCGTATCCGAAAAGCTTTAA
TTGATAAGCACCAGATTGAGGCAATAATTGGTTTTCCTGAAAAATTATTCTTAAATACACCAATACCTGTTTGTGTAGTT
ATTTTAAGAAAGAATCGTATTGAATCAGATGTTCTGTTTGTTGATGCGAGCAAAGGATTTGAGAAAATTAAGAAACAAAA
TAATTTACGTTCTGAAGATGTGGAAAAGATTGTTGATACAGTAATTAACCGTAAAGAGATAGAGAAATACTCACATGTAG
CAACTTTGGATGAAATAAAAGAAAATGATTACAATTTAAATATTCCTCGATATGTGGATACTTTTGAAGAAGAGGAGGCT
ATTGATTTGGTGGCGCTTGGTAATGAAATGGTTGCATTAAATGCTGATATTAAAAAAGCCGAGACTGATTTTCTTGGTTT
ATTAGATGAATTAGCTGTTACTGCGGATACGAAGGAAATAATTGAAGCTACTAAGGCGGTATTTCGATGA

Upstream 100 bases:

>100_bases
TTGAAGCCTCTGATTTTGAAGAAGAGCTAATGGCATTCTTCAATTCACTATAAGCAAATATGAGTTTTATTTATAATAAG
AGAAAGAAGGAAAAAACATA

Downstream 100 bases:

>100_bases
AAAAATTAGAAAAAAGCGTACCAGTAATCCGGTTTAAAGGCTTTTCTGAAGCTTGGGAACAGCGTAAGTTAGGTGAAATT
GCGAATTCCTTCGAATATGG

Product: HsdM type IC modification subunit

Products: NA

Alternate protein names: M.MpnORFDP [H]

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MALSTEQKTKMWAMLNQTRGQIGLTAYKDYIFGILFYKYLSEKATHWLNGVLRGENWESVYSQDSVKALNYMKKNLGYAI
QPNEFFVDWKKAIDTDRFNIGMMTDTFTHFNQQIAFEAKNDFEGIFDGMRFDSADLGANAQARASVMISMIELLSSPEFD
LSGSNDTVSDIYEYLVAQFATVLASDMGQYYTPKEISNVMARILTFGREDMEKFSIFDPTVGSGSLLLTTASYMKNSGRR
GVIKYYGQEKDATPYRLSRMNLMMHGIEYNDININHADTLESDWPDGVVDGKDTPRMFDAVMANPPYSAHWNNKDREDDP
RWREYGVSPKTKADYAFLLHCLYHLEDNGRMAIILPHGVLFRGASEGRIRKALIDKHQIEAIIGFPEKLFLNTPIPVCVV
ILRKNRIESDVLFVDASKGFEKIKKQNNLRSEDVEKIVDTVINRKEIEKYSHVATLDEIKENDYNLNIPRYVDTFEEEEA
IDLVALGNEMVALNADIKKAETDFLGLLDELAVTADTKEIIEATKAVFR

Sequences:

>Translated_529_residues
MALSTEQKTKMWAMLNQTRGQIGLTAYKDYIFGILFYKYLSEKATHWLNGVLRGENWESVYSQDSVKALNYMKKNLGYAI
QPNEFFVDWKKAIDTDRFNIGMMTDTFTHFNQQIAFEAKNDFEGIFDGMRFDSADLGANAQARASVMISMIELLSSPEFD
LSGSNDTVSDIYEYLVAQFATVLASDMGQYYTPKEISNVMARILTFGREDMEKFSIFDPTVGSGSLLLTTASYMKNSGRR
GVIKYYGQEKDATPYRLSRMNLMMHGIEYNDININHADTLESDWPDGVVDGKDTPRMFDAVMANPPYSAHWNNKDREDDP
RWREYGVSPKTKADYAFLLHCLYHLEDNGRMAIILPHGVLFRGASEGRIRKALIDKHQIEAIIGFPEKLFLNTPIPVCVV
ILRKNRIESDVLFVDASKGFEKIKKQNNLRSEDVEKIVDTVINRKEIEKYSHVATLDEIKENDYNLNIPRYVDTFEEEEA
IDLVALGNEMVALNADIKKAETDFLGLLDELAVTADTKEIIEATKAVFR
>Mature_528_residues
ALSTEQKTKMWAMLNQTRGQIGLTAYKDYIFGILFYKYLSEKATHWLNGVLRGENWESVYSQDSVKALNYMKKNLGYAIQ
PNEFFVDWKKAIDTDRFNIGMMTDTFTHFNQQIAFEAKNDFEGIFDGMRFDSADLGANAQARASVMISMIELLSSPEFDL
SGSNDTVSDIYEYLVAQFATVLASDMGQYYTPKEISNVMARILTFGREDMEKFSIFDPTVGSGSLLLTTASYMKNSGRRG
VIKYYGQEKDATPYRLSRMNLMMHGIEYNDININHADTLESDWPDGVVDGKDTPRMFDAVMANPPYSAHWNNKDREDDPR
WREYGVSPKTKADYAFLLHCLYHLEDNGRMAIILPHGVLFRGASEGRIRKALIDKHQIEAIIGFPEKLFLNTPIPVCVVI
LRKNRIESDVLFVDASKGFEKIKKQNNLRSEDVEKIVDTVINRKEIEKYSHVATLDEIKENDYNLNIPRYVDTFEEEEAI
DLVALGNEMVALNADIKKAETDFLGLLDELAVTADTKEIIEATKAVFR

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=257, Percent_Identity=26.0700389105058, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR004546 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 60370; Mature: 60239

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSTEQKTKMWAMLNQTRGQIGLTAYKDYIFGILFYKYLSEKATHWLNGVLRGENWESV
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
YSQDSVKALNYMKKNLGYAIQPNEFFVDWKKAIDTDRFNIGMMTDTFTHFNQQIAFEAKN
HCCHHHHHHHHHHHHCCCEECCCHHEEEHHHHCCCCCEEEEEHHHHHHHHCCEEEEECCC
DFEGIFDGMRFDSADLGANAQARASVMISMIELLSSPEFDLSGSNDTVSDIYEYLVAQFA
CHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
TVLASDMGQYYTPKEISNVMARILTFGREDMEKFSIFDPTVGSGSLLLTTASYMKNSGRR
HHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCEEEEEHHHHHCCCCC
GVIKYYGQEKDATPYRLSRMNLMMHGIEYNDININHADTLESDWPDGVVDGKDTPRMFDA
CEEEECCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
VMANPPYSAHWNNKDREDDPRWREYGVSPKTKADYAFLLHCLYHLEDNGRMAIILPHGVL
HHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEE
FRGASEGRIRKALIDKHQIEAIIGFPEKLFLNTPIPVCVVILRKNRIESDVLFVDASKGF
EECCCCCHHHHHHHHHHHHHHHHCCCHHHEECCCHHHHHHHHHHCCCCCCEEEEECHHHH
EKIKKQNNLRSEDVEKIVDTVINRKEIEKYSHVATLDEIKENDYNLNIPRYVDTFEEEEA
HHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHC
IDLVALGNEMVALNADIKKAETDFLGLLDELAVTADTKEIIEATKAVFR
EEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ALSTEQKTKMWAMLNQTRGQIGLTAYKDYIFGILFYKYLSEKATHWLNGVLRGENWESV
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
YSQDSVKALNYMKKNLGYAIQPNEFFVDWKKAIDTDRFNIGMMTDTFTHFNQQIAFEAKN
HCCHHHHHHHHHHHHCCCEECCCHHEEEHHHHCCCCCEEEEEHHHHHHHHCCEEEEECCC
DFEGIFDGMRFDSADLGANAQARASVMISMIELLSSPEFDLSGSNDTVSDIYEYLVAQFA
CHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
TVLASDMGQYYTPKEISNVMARILTFGREDMEKFSIFDPTVGSGSLLLTTASYMKNSGRR
HHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCEEEEEHHHHHCCCCC
GVIKYYGQEKDATPYRLSRMNLMMHGIEYNDININHADTLESDWPDGVVDGKDTPRMFDA
CEEEECCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
VMANPPYSAHWNNKDREDDPRWREYGVSPKTKADYAFLLHCLYHLEDNGRMAIILPHGVL
HHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEE
FRGASEGRIRKALIDKHQIEAIIGFPEKLFLNTPIPVCVVILRKNRIESDVLFVDASKGF
EECCCCCHHHHHHHHHHHHHHHHCCCHHHEECCCHHHHHHHHHHCCCCCCEEEEECHHHH
EKIKKQNNLRSEDVEKIVDTVINRKEIEKYSHVATLDEIKENDYNLNIPRYVDTFEEEEA
HHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHC
IDLVALGNEMVALNADIKKAETDFLGLLDELAVTADTKEIIEATKAVFR
EEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]