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The map label for this gene is rpe [H]

Identifier: 226223124

GI number: 226223124

Start: 531624

End: 532292

Strand: Direct

Name: rpe [H]

Synonym: Lm4b_00521

Alternate gene names: 226223124

Gene position: 531624-532292 (Clockwise)

Preceding gene: 226223123

Following gene: 226223125

Centisome position: 18.25

GC content: 40.66

Gene sequence:

>669_bases
ATGAAAATGATTGCGGCTTCCATTATGTGTGCAGACTCGCTTCATCTCGCTGACGAACTTCGCGCACTCGAACAAGCAAA
TGTAAAAATGCTCCATTGTGATGTGATGGATGGTGTTTTTGTGGAAAATGCAGCAATGGGCGCCTATGTCCTTCAAGATA
TAAAAAACAATACAGATATGCTACTAGATATCCACTTAGCTACAGTGAACCCTGATAAATTTGTGGATTTGTATGCGGCG
ATAAAGCCGGCTTATATGTCTTTCCACGTAGAAGCTTCACCTGATGTCGATGCGACTATAAAGCATATTCGTGCGCTAGG
AATCAAACCGTCCATCGCCATCAGCCCGGATACAGAGATTGAACAGATTTATCCATTTTTAGATAAAGTCGATATGGTTT
TAATGATGACCGTTAACCCAGGATTCGCCGGACAAAAATTTCAGCATCATGTCCTAGAAAAAATCAAGAAACTTCAAAGA
GAGCTTGAAAGTCACACCAATAAACCATTAATTGAAGTAGACGGTAATATTTTTGAAGAAACAGTTCGGTTGCTTGAACC
AATTGGCGCAGATGTCTATGTCGTTGGAACAGCCGCATTATTTAACGACAAGGCAGGTAGTTATACAGAAAAATTGGCGC
CACTCAGAGAAATTATCCAAGAAAGGTGA

Upstream 100 bases:

>100_bases
TACTCTTACTTGATACGTGGCTTGCGGCAGAATTTGAAGGTGGAAGACATAATACAAGGCTCGCGAAATTGGCGGAGCTT
GAGGAACCGGAGGAAGATAA

Downstream 100 bases:

>100_bases
GGGAAAATGCATTTAGATTCAGCTAATTTAGAAGACGTGAAAAAAATTCAAGCCAGCTCCATTTTTAAAGGAATTACAAC
GAACCCAACCATTTTAGTAA

Product: ribulose-5-phosphate 3 epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKMIAASIMCADSLHLADELRALEQANVKMLHCDVMDGVFVENAAMGAYVLQDIKNNTDMLLDIHLATVNPDKFVDLYAA
IKPAYMSFHVEASPDVDATIKHIRALGIKPSIAISPDTEIEQIYPFLDKVDMVLMMTVNPGFAGQKFQHHVLEKIKKLQR
ELESHTNKPLIEVDGNIFEETVRLLEPIGADVYVVGTAALFNDKAGSYTEKLAPLREIIQER

Sequences:

>Translated_222_residues
MKMIAASIMCADSLHLADELRALEQANVKMLHCDVMDGVFVENAAMGAYVLQDIKNNTDMLLDIHLATVNPDKFVDLYAA
IKPAYMSFHVEASPDVDATIKHIRALGIKPSIAISPDTEIEQIYPFLDKVDMVLMMTVNPGFAGQKFQHHVLEKIKKLQR
ELESHTNKPLIEVDGNIFEETVRLLEPIGADVYVVGTAALFNDKAGSYTEKLAPLREIIQER
>Mature_222_residues
MKMIAASIMCADSLHLADELRALEQANVKMLHCDVMDGVFVENAAMGAYVLQDIKNNTDMLLDIHLATVNPDKFVDLYAA
IKPAYMSFHVEASPDVDATIKHIRALGIKPSIAISPDTEIEQIYPFLDKVDMVLMMTVNPGFAGQKFQHHVLEKIKKLQR
ELESHTNKPLIEVDGNIFEETVRLLEPIGADVYVVGTAALFNDKAGSYTEKLAPLREIIQER

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=197, Percent_Identity=35.0253807106599, Blast_Score=121, Evalue=6e-28,
Organism=Homo sapiens, GI219879828, Length=199, Percent_Identity=32.6633165829146, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI24307923, Length=158, Percent_Identity=31.0126582278481, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1789788, Length=197, Percent_Identity=32.994923857868, Blast_Score=117, Evalue=4e-28,
Organism=Escherichia coli, GI1790523, Length=200, Percent_Identity=31.5, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790754, Length=153, Percent_Identity=29.4117647058824, Blast_Score=85, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17552948, Length=222, Percent_Identity=31.5315315315315, Blast_Score=116, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6322341, Length=211, Percent_Identity=34.1232227488152, Blast_Score=119, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24586301, Length=217, Percent_Identity=32.7188940092166, Blast_Score=114, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24764; Mature: 24764

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMIAASIMCADSLHLADELRALEQANVKMLHCDVMDGVFVENAAMGAYVLQDIKNNTDM
CCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHCCCHHHHHHHHHHHHHHHCCCCCE
LLDIHLATVNPDKFVDLYAAIKPAYMSFHVEASPDVDATIKHIRALGIKPSIAISPDTEI
EEEEEEEEECCHHHHHHHHHHCCHHEEEEEECCCCHHHHHHHHHHHCCCCCEEECCCCCH
EQIYPFLDKVDMVLMMTVNPGFAGQKFQHHVLEKIKKLQRELESHTNKPLIEVDGNIFEE
HHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHH
TVRLLEPIGADVYVVGTAALFNDKAGSYTEKLAPLREIIQER
HHHHHHHCCCCEEEEEEHHHHCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKMIAASIMCADSLHLADELRALEQANVKMLHCDVMDGVFVENAAMGAYVLQDIKNNTDM
CCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHCCCHHHHHHHHHHHHHHHCCCCCE
LLDIHLATVNPDKFVDLYAAIKPAYMSFHVEASPDVDATIKHIRALGIKPSIAISPDTEI
EEEEEEEEECCHHHHHHHHHHCCHHEEEEEECCCCHHHHHHHHHHHCCCCCEEECCCCCH
EQIYPFLDKVDMVLMMTVNPGFAGQKFQHHVLEKIKKLQRELESHTNKPLIEVDGNIFEE
HHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHH
TVRLLEPIGADVYVVGTAALFNDKAGSYTEKLAPLREIIQER
HHHHHHHCCCCEEEEEEHHHHCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]