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The map label for this gene is rpiB [H]

Identifier: 226223123

GI number: 226223123

Start: 531178

End: 531627

Strand: Direct

Name: rpiB [H]

Synonym: Lm4b_00520

Alternate gene names: 226223123

Gene position: 531178-531627 (Clockwise)

Preceding gene: 226223122

Following gene: 226223124

Centisome position: 18.24

GC content: 43.33

Gene sequence:

>450_bases
ATGGAAATTGCAATTGCAGCTGACCATGGCGGTTTTCAGCTGAAAGAAAAAATCCGCGCGCATTTAATTGAAAGCGGCTA
CACAGTAAAAGATTTTGGTTGTTATTCATTAGAAAGCGTGGATTTTCCAGAGTATGCCGCTAAAGTAGGACACTTTGTTG
CAACCGAAAACAGTTTAGGTGTGCTCTGTTGCGGAACAGGGATTGGAATGTCTATGGCAGCCAACAAAATAAAAGGTGTT
CGTGCTGCTGTTGTTTCAGATGCTTTTTCAGCAATGATGACGAGGCGACATAATAATAGTAATGTTCTTTGTCTTGGTGA
ACGTGTTCTGGGCGATAGTCTGGCGTTACTCTTACTTGATACGTGGCTTGCGGCAGAATTTGAAGGTGGAAGACATAATA
CAAGGCTCGCGAAATTGGCGGAGCTTGAGGAACCGGAGGAAGATAAATGA

Upstream 100 bases:

>100_bases
TACCATCTTGCGGATTCGAGTAGAGAAAAATGGTGACGAACAGTTCTAACAGTTTGAGGAAGGCCGGTGCTACAATCAAG
GTGAGAAAGGAGAGGATAAC

Downstream 100 bases:

>100_bases
AAATGATTGCGGCTTCCATTATGTGTGCAGACTCGCTTCATCTCGCTGACGAACTTCGCGCACTCGAACAAGCAAATGTA
AAAATGCTCCATTGTGATGT

Product: ribose 5-phosphate isomerase

Products: NA

Alternate protein names: Phosphoriboisomerase B [H]

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MEIAIAADHGGFQLKEKIRAHLIESGYTVKDFGCYSLESVDFPEYAAKVGHFVATENSLGVLCCGTGIGMSMAANKIKGV
RAAVVSDAFSAMMTRRHNNSNVLCLGERVLGDSLALLLLDTWLAAEFEGGRHNTRLAKLAELEEPEEDK

Sequences:

>Translated_149_residues
MEIAIAADHGGFQLKEKIRAHLIESGYTVKDFGCYSLESVDFPEYAAKVGHFVATENSLGVLCCGTGIGMSMAANKIKGV
RAAVVSDAFSAMMTRRHNNSNVLCLGERVLGDSLALLLLDTWLAAEFEGGRHNTRLAKLAELEEPEEDK
>Mature_149_residues
MEIAIAADHGGFQLKEKIRAHLIESGYTVKDFGCYSLESVDFPEYAAKVGHFVATENSLGVLCCGTGIGMSMAANKIKGV
RAAVVSDAFSAMMTRRHNNSNVLCLGERVLGDSLALLLLDTWLAAEFEGGRHNTRLAKLAELEEPEEDK

Specific function: In addition to its activity on D-ribose 5-phosphate it probably also has activity on D-allose 6-phosphate [H]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family [H]

Homologues:

Organism=Escherichia coli, GI1790528, Length=144, Percent_Identity=47.9166666666667, Blast_Score=144, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003500
- InterPro:   IPR004785 [H]

Pfam domain/function: PF02502 LacAB_rpiB [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 16133; Mature: 16133

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIAIAADHGGFQLKEKIRAHLIESGYTVKDFGCYSLESVDFPEYAAKVGHFVATENSLG
CEEEEECCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHEEEECCCCE
VLCCGTGIGMSMAANKIKGVRAAVVSDAFSAMMTRRHNNSNVLCLGERVLGDSLALLLLD
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHH
TWLAAEFEGGRHNTRLAKLAELEEPEEDK
HHHHHHCCCCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEIAIAADHGGFQLKEKIRAHLIESGYTVKDFGCYSLESVDFPEYAAKVGHFVATENSLG
CEEEEECCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHEEEECCCCE
VLCCGTGIGMSMAANKIKGVRAAVVSDAFSAMMTRRHNNSNVLCLGERVLGDSLALLLLD
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHH
TWLAAEFEGGRHNTRLAKLAELEEPEEDK
HHHHHHCCCCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8576032; 7610040; 9278503; 1840580; 7984428; 9401019 [H]