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The map label for this gene is dhaS [H]

Identifier: 226223103

GI number: 226223103

Start: 512284

End: 512844

Strand: Direct

Name: dhaS [H]

Synonym: Lm4b_00500

Alternate gene names: 226223103

Gene position: 512284-512844 (Clockwise)

Preceding gene: 226223102

Following gene: 226223104

Centisome position: 17.59

GC content: 39.39

Gene sequence:

>561_bases
ATGGCGGAATCACTCATTACTAAAAAAGCGATTGCTGGTGGGCTGATGGAGCTTTGTCAGCATAAGCGGTTTGAAAAGAT
TAGTATTGCGGATATTACGAATATTTGTGGTCTTAATCGGCAAACTTTTTACTATCATTTTACAGATAAATACGATTTGC
TTACTTGGACGTATGAAAATGATTTTTTCCATTGTTTGGCGGATGGGATTACGCTTGAAAATTGGGATAAGCATGTACTG
AAAATGCTGGAATCGATTAAAGAAAATGCTGATTTCTATAAAAACACGGTTTCGGCGGATGCGAGTATCCTTTCTTTTTG
CTTTTCTAAATTAACGAATTCGCTGTTTATGGATTTATTTGAGAAAATTGATACGAATGGAGCCGTGAACGAGGCGGACC
GGGTATTTTATGCGGAATTCTTTTCTTACGGATGCTCGGGTGTACTGATTAAATGGATTACGCGCGGTTTTAAAGAGGCA
CCGGAAACGATTGCGAACCAGCTATTTCGACTTGCGAAGGATACGGAATTTTTGGCAAACAGCATGTACCGCGAAAACTA
G

Upstream 100 bases:

>100_bases
AAGGAGATAATAAAGCACCAACCTCTCCCATGCTTTCCCTAGCAATTCCAACCCCACCTGAGATACAATTAACCCAAACA
AACGAAACGGGGCGGATGCC

Downstream 100 bases:

>100_bases
ACAATATGGCTAATTTGTCTAAAAACCAGACATAAGCGTTCTTTTGCCCAGATTAAAAGCGAACGACAAGCGGTATACTA
TCTGTATCAAGAAATTGGAG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MAESLITKKAIAGGLMELCQHKRFEKISIADITNICGLNRQTFYYHFTDKYDLLTWTYENDFFHCLADGITLENWDKHVL
KMLESIKENADFYKNTVSADASILSFCFSKLTNSLFMDLFEKIDTNGAVNEADRVFYAEFFSYGCSGVLIKWITRGFKEA
PETIANQLFRLAKDTEFLANSMYREN

Sequences:

>Translated_186_residues
MAESLITKKAIAGGLMELCQHKRFEKISIADITNICGLNRQTFYYHFTDKYDLLTWTYENDFFHCLADGITLENWDKHVL
KMLESIKENADFYKNTVSADASILSFCFSKLTNSLFMDLFEKIDTNGAVNEADRVFYAEFFSYGCSGVLIKWITRGFKEA
PETIANQLFRLAKDTEFLANSMYREN
>Mature_185_residues
AESLITKKAIAGGLMELCQHKRFEKISIADITNICGLNRQTFYYHFTDKYDLLTWTYENDFFHCLADGITLENWDKHVLK
MLESIKENADFYKNTVSADASILSFCFSKLTNSLFMDLFEKIDTNGAVNEADRVFYAEFFSYGCSGVLIKWITRGFKEAP
ETIANQLFRLAKDTEFLANSMYREN

Specific function: In complex with dhaQ, upon activation by dihydroxyacetone, activates transcription of the dhaKLM operon. Binds the inverted repeat sequence 5'-GGACACATN(6)ATTTGTCC-3' located upstream of and partially overlapping with the -35 promoter sequence of the dhaK

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR012738
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21527; Mature: 21395

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAESLITKKAIAGGLMELCQHKRFEKISIADITNICGLNRQTFYYHFTDKYDLLTWTYEN
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEECCCEEEEEEEECC
DFFHCLADGITLENWDKHVLKMLESIKENADFYKNTVSADASILSFCFSKLTNSLFMDLF
CHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKIDTNGAVNEADRVFYAEFFSYGCSGVLIKWITRGFKEAPETIANQLFRLAKDTEFLAN
HHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMYREN
HHHCCC
>Mature Secondary Structure 
AESLITKKAIAGGLMELCQHKRFEKISIADITNICGLNRQTFYYHFTDKYDLLTWTYEN
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEECCCEEEEEEEECC
DFFHCLADGITLENWDKHVLKMLESIKENADFYKNTVSADASILSFCFSKLTNSLFMDLF
CHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKIDTNGAVNEADRVFYAEFFSYGCSGVLIKWITRGFKEAPETIANQLFRLAKDTEFLAN
HHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMYREN
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]