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The map label for this gene is dhaM [H]

Identifier: 226222977

GI number: 226222977

Start: 378476

End: 378853

Strand: Reverse

Name: dhaM [H]

Synonym: Lm4b_00369

Alternate gene names: 226222977

Gene position: 378853-378476 (Counterclockwise)

Preceding gene: 226222981

Following gene: 226222976

Centisome position: 13.01

GC content: 39.95

Gene sequence:

>378_bases
ATGATAAGTATTGTTTTAGTATCTCACAGTCAAAAAATCACAGAAGGCCTCCAAGAAATGATTGTTGAAATGGTTGGAGA
TACAGTACATATTATTTCCTCTGGCGGAACTGGCGACGGGCGTCTTGGCACAAATGCAATCATGATAGCTGATAACATCG
CGACTTGCACTAATTCTGAACATATTTATATTTTTTGCGATATTGGAAGCGCTATCTTAAGTGCCGAAACAGCACTCGAA
TTATTAGAAACTGACCTCCTTGAAAAAACAACCATCATCGATGCCCCACTTGTTGAAGGCGCATTTACTGCCGCTGTTCA
ATCTCTCGTTAATCCATCCAAAGAAGCTATCCTACAAGAACTCACAAACGTGCATTAA

Upstream 100 bases:

>100_bases
TTATAAAACACAACAAAAGATAGCACTTTACAATAAAAAACAAGTATGTTAGGATATAAATAGCAATTAAACACAATTAA
AAACAGAAAGGAGCAACCAA

Downstream 100 bases:

>100_bases
AAACGTAATAAAACGCAATTTTGTAACTGGGAACTATGTAAATTAATTTTTACATGACAATACTATTTTCGAAAGGAGTT
TATTATGAAATTCTTTAGAG

Product: phosphotransferase mannnose-specific family component IIA

Products: NA

Alternate protein names: Phosphocarrier protein HPr; Protein H; Phosphotransferase enzyme IIA component; PTS system EIIA component [H]

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MISIVLVSHSQKITEGLQEMIVEMVGDTVHIISSGGTGDGRLGTNAIMIADNIATCTNSEHIYIFCDIGSAILSAETALE
LLETDLLEKTTIIDAPLVEGAFTAAVQSLVNPSKEAILQELTNVH

Sequences:

>Translated_125_residues
MISIVLVSHSQKITEGLQEMIVEMVGDTVHIISSGGTGDGRLGTNAIMIADNIATCTNSEHIYIFCDIGSAILSAETALE
LLETDLLEKTTIIDAPLVEGAFTAAVQSLVNPSKEAILQELTNVH
>Mature_125_residues
MISIVLVSHSQKITEGLQEMIVEMVGDTVHIISSGGTGDGRLGTNAIMIADNIATCTNSEHIYIFCDIGSAILSAETALE
LLETDLLEKTTIIDAPLVEGAFTAAVQSLVNPSKEAILQELTNVH

Specific function: Phosphotransferase subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. DhaM serves as the phosphoryl donor. It is phosphorylated by HPr, then it donates its phosphoryl group to dhaL-ADP, which eventually tran

COG id: COG3412

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI226510935, Length=111, Percent_Identity=37.8378378378378, Blast_Score=79, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012844
- InterPro:   IPR008279
- InterPro:   IPR004701
- InterPro:   IPR001020
- InterPro:   IPR005698
- InterPro:   IPR000032
- InterPro:   IPR008731 [H]

Pfam domain/function: PF03610 EIIA-man; PF05524 PEP-utilisers_N; PF00391 PEP-utilizers; PF00381 PTS-HPr [H]

EC number: NA

Molecular weight: Translated: 13237; Mature: 13237

Theoretical pI: Translated: 4.01; Mature: 4.01

Prosite motif: PS51096 PTS_EIIA_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISIVLVSHSQKITEGLQEMIVEMVGDTVHIISSGGTGDGRLGTNAIMIADNIATCTNSE
CEEEEEECCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCEEEEECCCEECCCCC
HIYIFCDIGSAILSAETALELLETDLLEKTTIIDAPLVEGAFTAAVQSLVNPSKEAILQE
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHH
LTNVH
HHCCC
>Mature Secondary Structure
MISIVLVSHSQKITEGLQEMIVEMVGDTVHIISSGGTGDGRLGTNAIMIADNIATCTNSE
CEEEEEECCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCEEEEECCCEECCCCC
HIYIFCDIGSAILSAETALELLETDLLEKTTIIDAPLVEGAFTAAVQSLVNPSKEAILQE
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHH
LTNVH
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 2671658; 7984428 [H]