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The map label for this gene is macB [H]

Identifier: 226222824

GI number: 226222824

Start: 194891

End: 196099

Strand: Direct

Name: macB [H]

Synonym: Lm4b_00192

Alternate gene names: 226222824

Gene position: 194891-196099 (Clockwise)

Preceding gene: 226222823

Following gene: 226222825

Centisome position: 6.69

GC content: 38.71

Gene sequence:

>1209_bases
ATGAATGTTCTCCAAAGCATGAAAATGGCATGGAAACAATTAAAGGCAAGTAAATTAAGGTCTTTTCTAACCATGCTAGG
TATTATTATTGGTGTCGCATCCGTTATTCTTTTAGTATCTCTAGGGAATGGTGTAACGCAAGAAGTTGATGACCAAATGG
GCGATTTGGGTTCGAATTTAATTACAGTAGTTAATAGCTCTGTTAATCCAAACGACAAATATACGTATGATGAAGTAATG
AAATATCAAAACATTGATGGAGTCAAAAGCGTTTCTCCAGAATTATCTGGACAAGTCAATGCAACTTTTGATTATAAGAA
TTCAAGTAATAAGGTGATAGGCACGAATGACCAATATAAGGCCGCGCGTAGCCTAGAAATGAAAGAAGGGCGTTTCCTAC
TACCGATTGATACCGAATATGGCCAGAAAGTAGCTGTAATAGGCTCTACGGTAGCAAGTGATCTATTTGGTTTTGGGGAT
CCGATTGGCGAAACCATTAGATTAAACGGAATGCCTTACAAAGTTGTTGGTGTCTTGAAAGAAAAAGGCGCGTCTATGAT
GGGATCGAGCGATGACCAAATCTTTATTCCGATTTCTTCCGCTCAAAGGCTCCTAAAAGATACAAATGTCCGTACAATCT
ATGTAGAAACAAAATCTGCCGAAGATGTTGATTTTGTAGTAAACACACTAGAATCACGTCTTGCGATTAAATTTGGTGAC
GAAAAAGAACAAGAAAAAAATGCGTCATCCGCACAAATGGGACCATCTTATCAAGTCATTAATCAACAAGAGATTCTCAA
TGCTTTCAACACGATTAGTACAACGCTAACTACTGCGCTTGGTGCGATTGCTGCTATTTCACTTGTTGTTGGTGGTATTG
GAATTATGAATATTATGCTAGTTTCTGTTAGTGAGCGAACGAGAGAGATTGGTATAAGAAAAGCGCTCGGAGCTAAAAAA
CGAGCCATCCTGTTACAATTCCTAATTGAATCCATTGTTATTAGTGTCTGTGGTGGGATTATCGGTATTATTATCGGGGT
CTCAGGAGCGCTCATATTTGGCTCAGTCGCAGGTATATCGTCAGGAATAACTGCAGGAACCATTATCTTCTCCTTCGTAT
TCTCACTATGTATCGGAGTGATATTTGGTATCGCACCTGCTAATAAAGCTTCGAAATTAAGACCAATTGACGCATTAAGA
TCCGAATAA

Upstream 100 bases:

>100_bases
CCATCGTTATGATTACGCATGATCCAACAATCGCCTCATACGGTACAAGAAGTATCCGTATTCAAGATGGTAAATTATTC
CATGAGGAGGCGACGCAAGC

Downstream 100 bases:

>100_bases
ATAAAAGAAGCCTGAAATAAGCTGTTTCGGGCTTCTTTTTTTACTAAAATTAGCTACTAAGTTGTCTTGTCATCTATATT
TAATCTTTTGTCACAATAAA

Product: membrane protein (ABC transporter component)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MNVLQSMKMAWKQLKASKLRSFLTMLGIIIGVASVILLVSLGNGVTQEVDDQMGDLGSNLITVVNSSVNPNDKYTYDEVM
KYQNIDGVKSVSPELSGQVNATFDYKNSSNKVIGTNDQYKAARSLEMKEGRFLLPIDTEYGQKVAVIGSTVASDLFGFGD
PIGETIRLNGMPYKVVGVLKEKGASMMGSSDDQIFIPISSAQRLLKDTNVRTIYVETKSAEDVDFVVNTLESRLAIKFGD
EKEQEKNASSAQMGPSYQVINQQEILNAFNTISTTLTTALGAIAAISLVVGGIGIMNIMLVSVSERTREIGIRKALGAKK
RAILLQFLIESIVISVCGGIIGIIIGVSGALIFGSVAGISSGITAGTIIFSFVFSLCIGVIFGIAPANKASKLRPIDALR
SE

Sequences:

>Translated_402_residues
MNVLQSMKMAWKQLKASKLRSFLTMLGIIIGVASVILLVSLGNGVTQEVDDQMGDLGSNLITVVNSSVNPNDKYTYDEVM
KYQNIDGVKSVSPELSGQVNATFDYKNSSNKVIGTNDQYKAARSLEMKEGRFLLPIDTEYGQKVAVIGSTVASDLFGFGD
PIGETIRLNGMPYKVVGVLKEKGASMMGSSDDQIFIPISSAQRLLKDTNVRTIYVETKSAEDVDFVVNTLESRLAIKFGD
EKEQEKNASSAQMGPSYQVINQQEILNAFNTISTTLTTALGAIAAISLVVGGIGIMNIMLVSVSERTREIGIRKALGAKK
RAILLQFLIESIVISVCGGIIGIIIGVSGALIFGSVAGISSGITAGTIIFSFVFSLCIGVIFGIAPANKASKLRPIDALR
SE
>Mature_402_residues
MNVLQSMKMAWKQLKASKLRSFLTMLGIIIGVASVILLVSLGNGVTQEVDDQMGDLGSNLITVVNSSVNPNDKYTYDEVM
KYQNIDGVKSVSPELSGQVNATFDYKNSSNKVIGTNDQYKAARSLEMKEGRFLLPIDTEYGQKVAVIGSTVASDLFGFGD
PIGETIRLNGMPYKVVGVLKEKGASMMGSSDDQIFIPISSAQRLLKDTNVRTIYVETKSAEDVDFVVNTLESRLAIKFGD
EKEQEKNASSAQMGPSYQVINQQEILNAFNTISTTLTTALGAIAAISLVVGGIGIMNIMLVSVSERTREIGIRKALGAKK
RAILLQFLIESIVISVCGGIIGIIIGVSGALIFGSVAGISSGITAGTIIFSFVFSLCIGVIFGIAPANKASKLRPIDALR
SE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=408, Percent_Identity=32.3529411764706, Blast_Score=183, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42989; Mature: 42989

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLQSMKMAWKQLKASKLRSFLTMLGIIIGVASVILLVSLGNGVTQEVDDQMGDLGSNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHH
ITVVNSSVNPNDKYTYDEVMKYQNIDGVKSVSPELSGQVNATFDYKNSSNKVIGTNDQYK
HHEECCCCCCCCCCCHHHHHHHCCCCCHHHCCCCCCCCEEEEEEECCCCCCEECCCCHHH
AARSLEMKEGRFLLPIDTEYGQKVAVIGSTVASDLFGFGDPIGETIRLNGMPYKVVGVLK
HHHHHHHCCCCEEEEECCCCCCEEEEHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHH
EKGASMMGSSDDQIFIPISSAQRLLKDTNVRTIYVETKSAEDVDFVVNTLESRLAIKFGD
HCCCHHCCCCCCEEEEEHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHEEEEECC
EKEQEKNASSAQMGPSYQVINQQEILNAFNTISTTLTTALGAIAAISLVVGGIGIMNIML
HHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVSERTREIGIRKALGAKKRAILLQFLIESIVISVCGGIIGIIIGVSGALIFGSVAGIS
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SGITAGTIIFSFVFSLCIGVIFGIAPANKASKLRPIDALRSE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCC
>Mature Secondary Structure
MNVLQSMKMAWKQLKASKLRSFLTMLGIIIGVASVILLVSLGNGVTQEVDDQMGDLGSNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHH
ITVVNSSVNPNDKYTYDEVMKYQNIDGVKSVSPELSGQVNATFDYKNSSNKVIGTNDQYK
HHEECCCCCCCCCCCHHHHHHHCCCCCHHHCCCCCCCCEEEEEEECCCCCCEECCCCHHH
AARSLEMKEGRFLLPIDTEYGQKVAVIGSTVASDLFGFGDPIGETIRLNGMPYKVVGVLK
HHHHHHHCCCCEEEEECCCCCCEEEEHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHH
EKGASMMGSSDDQIFIPISSAQRLLKDTNVRTIYVETKSAEDVDFVVNTLESRLAIKFGD
HCCCHHCCCCCCEEEEEHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHEEEEECC
EKEQEKNASSAQMGPSYQVINQQEILNAFNTISTTLTTALGAIAAISLVVGGIGIMNIML
HHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVSERTREIGIRKALGAKKRAILLQFLIESIVISVCGGIIGIIIGVSGALIFGSVAGIS
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SGITAGTIIFSFVFSLCIGVIFGIAPANKASKLRPIDALRSE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA