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The map label for this gene is rsbRD [H]

Identifier: 226222794

GI number: 226222794

Start: 161988

End: 162824

Strand: Reverse

Name: rsbRD [H]

Synonym: Lm4b_00162

Alternate gene names: 226222794

Gene position: 162824-161988 (Counterclockwise)

Preceding gene: 226222801

Following gene: 226222790

Centisome position: 5.59

GC content: 37.51

Gene sequence:

>837_bases
ATGAATGAATCGAATGGAAGTATGGAGCTATATTTAAGAGAACATACCGAAGAAATTATTAATAAGTGGCTATCCAAAAT
TTATGAAAACGAAAACACGTATACTAGTTTTGTTTACTCGCCGCGTTACAAAGATGAACTGCGCGCTGACAGTGAACAAA
CAGCGGACTTAATCATTTCTTATTTCGCTGGTAAAAAAGCATTTTTTGAGAAACTCGACAAATGGCTGGATAACATGTAC
GCGCGTCGCATGGAAAATGAAGTACCATTACCTGAAGTTATTACCACCCTTGATAAACTACGCCGTGAATTTGTTTCTGC
TGTTGGTGATTTTTGTATTCATAATGATGAAGTGTCTAAATGTGATTTCTCATCAAGTCTGTCCATGGTTAATCACGGGT
TTGACCGGATAAACGAAGCCTTCTCCGCCATGTATTACAATGATATCGTCAAACATTTAGAACAACAACATCGTTTAATA
GAAGAAATTAGCACACCCGTCATTTCTATCACGGACAAATTAGCGATCCTTCCTTTGATGGGGAGCGTCGACCGTGAAAG
AGCAGAAAAGTTATCCGAAATCACGGCAAACAAATGCGTACACTTAGGCGTGGAACAATTGTGTATTGATTTATCAGGAA
TTACTTATTTTGATGATGCACTTGGAGAAATGCTTACCAACTTAGTGACGATGCTTAAACTTCTTGGTGTCGAGGCATTT
ATTTCTGGCATCCAACCAAAAATGGCACAACAAATTAATCGTGTTGAATTAAACTTATCTATTCCTGCCTATCATTCGTT
AAAGGCTGTCTTACAAGATCAAACTAGAACTATATAA

Upstream 100 bases:

>100_bases
AATTAGTTATTTTTCTAAAATTTAATTGGACAGTACAACGTTTTGAGCATAGAATAAAGAAAAGTAGTTATTATACTTAG
ACTTAAAGGGGTTGTCTGGT

Downstream 100 bases:

>100_bases
GAAAAACCGTAAGCGATTGTATTATCGCTTACGGTTTTTTGATTATTTTCTTCTAAGTGCAATTAATCCACTCGCTGAAA
TGGCTACGAGCAGTATTCCC

Product: hypothetical protein

Products: NA

Alternate protein names: Stressosome protein rsbRD [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MNESNGSMELYLREHTEEIINKWLSKIYENENTYTSFVYSPRYKDELRADSEQTADLIISYFAGKKAFFEKLDKWLDNMY
ARRMENEVPLPEVITTLDKLRREFVSAVGDFCIHNDEVSKCDFSSSLSMVNHGFDRINEAFSAMYYNDIVKHLEQQHRLI
EEISTPVISITDKLAILPLMGSVDRERAEKLSEITANKCVHLGVEQLCIDLSGITYFDDALGEMLTNLVTMLKLLGVEAF
ISGIQPKMAQQINRVELNLSIPAYHSLKAVLQDQTRTI

Sequences:

>Translated_278_residues
MNESNGSMELYLREHTEEIINKWLSKIYENENTYTSFVYSPRYKDELRADSEQTADLIISYFAGKKAFFEKLDKWLDNMY
ARRMENEVPLPEVITTLDKLRREFVSAVGDFCIHNDEVSKCDFSSSLSMVNHGFDRINEAFSAMYYNDIVKHLEQQHRLI
EEISTPVISITDKLAILPLMGSVDRERAEKLSEITANKCVHLGVEQLCIDLSGITYFDDALGEMLTNLVTMLKLLGVEAF
ISGIQPKMAQQINRVELNLSIPAYHSLKAVLQDQTRTI
>Mature_278_residues
MNESNGSMELYLREHTEEIINKWLSKIYENENTYTSFVYSPRYKDELRADSEQTADLIISYFAGKKAFFEKLDKWLDNMY
ARRMENEVPLPEVITTLDKLRREFVSAVGDFCIHNDEVSKCDFSSSLSMVNHGFDRINEAFSAMYYNDIVKHLEQQHRLI
EEISTPVISITDKLAILPLMGSVDRERAEKLSEITANKCVHLGVEQLCIDLSGITYFDDALGEMLTNLVTMLKLLGVEAF
ISGIQPKMAQQINRVELNLSIPAYHSLKAVLQDQTRTI

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 31938; Mature: 31938

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESNGSMELYLREHTEEIINKWLSKIYENENTYTSFVYSPRYKDELRADSEQTADLIIS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHCCHHHHHHHHHH
YFAGKKAFFEKLDKWLDNMYARRMENEVPLPEVITTLDKLRREFVSAVGDFCIHNDEVSK
HHHCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
CDFSSSLSMVNHGFDRINEAFSAMYYNDIVKHLEQQHRLIEEISTPVISITDKLAILPLM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GSVDRERAEKLSEITANKCVHLGVEQLCIDLSGITYFDDALGEMLTNLVTMLKLLGVEAF
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ISGIQPKMAQQINRVELNLSIPAYHSLKAVLQDQTRTI
HHCCCHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNESNGSMELYLREHTEEIINKWLSKIYENENTYTSFVYSPRYKDELRADSEQTADLIIS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHCCHHHHHHHHHH
YFAGKKAFFEKLDKWLDNMYARRMENEVPLPEVITTLDKLRREFVSAVGDFCIHNDEVSK
HHHCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
CDFSSSLSMVNHGFDRINEAFSAMYYNDIVKHLEQQHRLIEEISTPVISITDKLAILPLM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GSVDRERAEKLSEITANKCVHLGVEQLCIDLSGITYFDDALGEMLTNLVTMLKLLGVEAF
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ISGIQPKMAQQINRVELNLSIPAYHSLKAVLQDQTRTI
HHCCCHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 11157946 [H]