Click here to switch to the map view.

The map label for this gene is ccpA [H]

Identifier: 225861818

GI number: 225861818

Start: 1853036

End: 1854046

Strand: Reverse

Name: ccpA [H]

Synonym: SPT_1980

Alternate gene names: 225861818

Gene position: 1854046-1853036 (Counterclockwise)

Preceding gene: 225861819

Following gene: 225861817

Centisome position: 87.78

GC content: 41.05

Gene sequence:

>1011_bases
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGCTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCGCTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Upstream 100 bases:

>100_bases
ACGAAATTTTCACATCTTCACTTTTGTAAGTAGATATAGAGCTTCAATCAGTACCTCTACTTGTAAAAGAATGTGTGAGA
TAGAAAGGACAGGAAAAGGA

Downstream 100 bases:

>100_bases
AAAAAATCAGGGAATCGAGAAGATTTCCTGATTTTGTGCTCTTAAACAAGAGATGTTGACTTAATGAATACCATAGAGCG
GACTAGGCGGCTGGTTAAAG

Product: catabolite control protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Sequences:

>Translated_336_residues
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK
>Mature_336_residues
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes and in the positive regulation of genes involved in excretion of excess carbon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=329, Percent_Identity=30.6990881458967, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1790194, Length=343, Percent_Identity=31.1953352769679, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1789068, Length=297, Percent_Identity=33.3333333333333, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1788474, Length=301, Percent_Identity=31.5614617940199, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1787948, Length=343, Percent_Identity=29.1545189504373, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1789202, Length=292, Percent_Identity=29.4520547945205, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1786540, Length=337, Percent_Identity=29.9703264094956, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787580, Length=313, Percent_Identity=27.7955271565495, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1790715, Length=304, Percent_Identity=26.6447368421053, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI48994940, Length=313, Percent_Identity=26.517571884984, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787906, Length=341, Percent_Identity=25.5131964809384, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789456, Length=340, Percent_Identity=26.7647058823529, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786268, Length=290, Percent_Identity=25.8620689655172, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37043; Mature: 37043

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLA
CCCCCCEEEEEHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCC
SKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQ
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHH
VDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPSVNIDYKQATIDAVSYLAKEN
CCCEEEEEEHHHHHHHHHHHHCCCCEEEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHCC
ERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGLVFESKYSYDDGYALAERLISSN
CEEEEEECCCEECCCCCEEEEEHHHHHHHCCCEECCCEEEECCCCCCCHHHHHHHHHCCC
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGA
CCEEEEECHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHCCCCHHHHHHHHHHHHH
ISMRMLTKIMHKEELEEREVLLPHGLTERSSTRKRK
HHHHHHHHHHHHHHHHHHCEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLA
CCCCCCEEEEEHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCC
SKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQ
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHH
VDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPSVNIDYKQATIDAVSYLAKEN
CCCEEEEEEHHHHHHHHHHHHCCCCEEEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHCC
ERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGLVFESKYSYDDGYALAERLISSN
CEEEEEECCCEECCCCCEEEEEHHHHHHHCCCEECCCEEEECCCCCCCHHHHHHHHHCCC
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGA
CCEEEEECHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHCCCCHHHHHHHHHHHHH
ISMRMLTKIMHKEELEEREVLLPHGLTERSSTRKRK
HHHHHHHHHHHHHHHHHHCEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12397186 [H]