Click here to switch to the map view.

The map label for this gene is yfbQ [C]

Identifier: 225861812

GI number: 225861812

Start: 1847968

End: 1849182

Strand: Reverse

Name: yfbQ [C]

Synonym: SPT_1974

Alternate gene names: 225861812

Gene position: 1849182-1847968 (Counterclockwise)

Preceding gene: 225861813

Following gene: 225861811

Centisome position: 87.55

GC content: 44.61

Gene sequence:

>1215_bases
ATGAAAGAATATAACAAGTCTAGTAAGTTAGAGCATGTTGCTTATGATATCCGTGGTCCTGTATTGGAAGAAGCCATGCG
GATGCGAGCGAATGGAGAAAAGATTTTACGTCTGAATACAGGAAATCCAGCAGAATTTGGCTTTACAGCGCCAGACGAGG
TCATTCATGACTTGATTATGAATGCGCGTGATAGTGAAGGCTATTCTAACTCCAAAGGGATTTTCTCAGCCCGTAAGGCC
ATCATGCAGTATTGCCAGCTGAAGAAATTCCCAAACGTAGATATTGATGATATTTACCTTGGAAATGGTGTCAGTGAGTT
GATTGTCATGTCCATGCAGGGGCTTTTGGACAATGGGGATGAGGTCTTAGTGCCAATGCCAGACTATCCTCTATGGACGG
CGGCTGTCAGCCTAGCTGGAGGAAATGCCGTTCACTATATCTGTGATGAAGCTGTGGAATGGTACCCAGATATTGACGAT
ATCAAGTCAAAAATCACTTCCAATACCAAGGCAATTGTCCTTATCAATCCAAATAACCCAACTGGAGCCCTTTATCCTAA
GGAACTCTTGCTGGAGATTATTGAGATTGCCCGTCAAAACGATTTGATTATCTTTGCGGATGAAATCTATGACCGCATGG
TAATGGACGGACATGTGCATACGCCTGTGGCGAGCTTGGCATCAGATGTCTTCTGTGTCAGCATGAATGGTCTGTCAAAA
TCCCACCGCATAGCAGGTTTCCGTGTGGGTTGGATGGTCTTGTCTGGCCCTAAGACTCATGTTAAGGGCTATATCGAAGG
GCTCAATATGCTGTCCAATATGCGCCTTTGCTCTAACGTTTTGGCCCAACAAGTCGTACAAACTTCCTTGGGGGGTCACC
AATCAGTCGATGAATTGCTTCTTCCTGGTGGACGAATCTACGAGCAAAGAAATTTCATCTATAATGCCATTCAAGATATT
CCAGGTTTGTCTGCCGTTAAACCCAAGGCGGGGCTCTATATCTTCCCAAAAATCGACCGCAATATGTACCGTATCGATGA
TGATGAGCAGTTTGTCCTTGATTTCTTGAAGCAGGAAAAGGTTCTCTTGGTTCATGGTCGAGGCTTTAACTGGCAGGAAC
CAGACCACTTCCGTATCGTTTACCTTCCTCGTGTTGATGAGTTAGCCCAAATCCAAGAAAAGATGACTCGTTTCTTGAAA
CAGTATCGTAGATAG

Upstream 100 bases:

>100_bases
GTTTTTCTTCTATACGAAACTAGTAACACATTTCAGTAAACTTGTCGCATTCTCTTTCTAGTGGTATAATGTTACTATCC
TGATGAATTGAGGAAACAAG

Downstream 100 bases:

>100_bases
GGCTTGCATTCGAAAAAGCTGGAAACATTTGCCTAGAGCTATTGACAAAAGTGAAAGAATCAGATAGAATAGTAAAGTAT
GTTTAGTAACTGATCACTTT

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPAEFGFTAPDEVIHDLIMNARDSEGYSNSKGIFSARKA
IMQYCQLKKFPNVDIDDIYLGNGVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGHVHTPVASLASDVFCVSMNGLSK
SHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRLCSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDI
PGLSAVKPKAGLYIFPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQEKMTRFLK
QYRR

Sequences:

>Translated_404_residues
MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPAEFGFTAPDEVIHDLIMNARDSEGYSNSKGIFSARKA
IMQYCQLKKFPNVDIDDIYLGNGVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGHVHTPVASLASDVFCVSMNGLSK
SHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRLCSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDI
PGLSAVKPKAGLYIFPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQEKMTRFLK
QYRR
>Mature_404_residues
MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPAEFGFTAPDEVIHDLIMNARDSEGYSNSKGIFSARKA
IMQYCQLKKFPNVDIDDIYLGNGVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGHVHTPVASLASDVFCVSMNGLSK
SHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRLCSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDI
PGLSAVKPKAGLYIFPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQEKMTRFLK
QYRR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=394, Percent_Identity=26.3959390862944, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI19263340, Length=369, Percent_Identity=25.7452574525745, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI215599424, Length=369, Percent_Identity=25.7452574525745, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI4885351, Length=357, Percent_Identity=24.9299719887955, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI95147551, Length=161, Percent_Identity=31.055900621118, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI169881279, Length=161, Percent_Identity=31.055900621118, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI56713256, Length=265, Percent_Identity=23.3962264150943, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI56713254, Length=265, Percent_Identity=23.3962264150943, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI169881281, Length=123, Percent_Identity=34.1463414634146, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI149944424, Length=352, Percent_Identity=24.1477272727273, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=61.6336633663366, Blast_Score=540, Evalue=1e-155,
Organism=Escherichia coli, GI1788722, Length=398, Percent_Identity=26.3819095477387, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1786816, Length=244, Percent_Identity=22.5409836065574, Blast_Score=72, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17567663, Length=382, Percent_Identity=28.2722513089005, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI71981209, Length=389, Percent_Identity=23.3933161953728, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17567369, Length=170, Percent_Identity=31.7647058823529, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994472, Length=179, Percent_Identity=32.4022346368715, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994476, Length=179, Percent_Identity=32.4022346368715, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71981215, Length=160, Percent_Identity=27.5, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6323118, Length=377, Percent_Identity=27.3209549071618, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6320317, Length=384, Percent_Identity=26.0416666666667, Blast_Score=112, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6322401, Length=170, Percent_Identity=26.4705882352941, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI18859735, Length=399, Percent_Identity=26.5664160401003, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24641770, Length=379, Percent_Identity=27.7044854881267, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24641760, Length=379, Percent_Identity=27.7044854881267, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24641768, Length=379, Percent_Identity=27.7044854881267, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24641766, Length=379, Percent_Identity=27.7044854881267, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24641764, Length=379, Percent_Identity=27.7044854881267, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI45551451, Length=379, Percent_Identity=27.7044854881267, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI28573069, Length=326, Percent_Identity=23.6196319018405, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646114, Length=326, Percent_Identity=23.6196319018405, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573067, Length=326, Percent_Identity=23.6196319018405, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573065, Length=326, Percent_Identity=23.6196319018405, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45731; Mature: 45731

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPAEFGFTAPDEVIHDLIM
CCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NARDSEGYSNSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGNGVSELIVMSMQGLLDNGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCC
EVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDDIKSKITSNTKAIVLINPNNP
EEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCC
TGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGHVHTPVASLASDVFCVSMNGLSK
CCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCHHHHHCCEEEEEECCCCC
SHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRLCSNVLAQQVVQTSLGGHQSVDELL
CCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYIFPKIDRNMYRIDDDEQFVLDFLKQEK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEECCCCHHHHHHHHCCCC
VLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQEKMTRFLKQYRR
EEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPAEFGFTAPDEVIHDLIM
CCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NARDSEGYSNSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGNGVSELIVMSMQGLLDNGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCC
EVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDDIKSKITSNTKAIVLINPNNP
EEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCC
TGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGHVHTPVASLASDVFCVSMNGLSK
CCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCHHHHHCCEEEEEECCCCC
SHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRLCSNVLAQQVVQTSLGGHQSVDELL
CCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYIFPKIDRNMYRIDDDEQFVLDFLKQEK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEECCCCHHHHHHHHCCCC
VLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQEKMTRFLKQYRR
EEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]