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The map label for this gene is 225861561

Identifier: 225861561

GI number: 225861561

Start: 1602257

End: 1603870

Strand: Reverse

Name: 225861561

Synonym: SPT_1677

Alternate gene names: NA

Gene position: 1603870-1602257 (Counterclockwise)

Preceding gene: 225861562

Following gene: 225861560

Centisome position: 75.94

GC content: 44.49

Gene sequence:

>1614_bases
ATGGAGATCATGTCGCTTGCGATTGCTGTTTTTGCCGTCATCATTGGTTTAGTCATTGGATATGTCAGCATCTCAGCTAA
GATGAAATCATCTCAGGAAGCTGCAGAGTTGATGCTTTTAAATGCTGAACAAGAAGCAACTAATTTACGTGGACAAGCTG
AGCGTGAAGCGGATTTACTTATTAATGAAGCCAAACGTGAAAGCAAGTCTCTTAAAAAAGAAGCACTATTGGAGGCCAAA
GAAGAAGCCAGAAAATACCGTGAAGAAGTGGACGCTGAATTCAAATCAGAACGTCAAGAACTCAAACAAATCGAAAGTCG
TTTGACAGAGAGAGCTACTAGCCTTGACCGTAAGGACGACAATTTGACGAGTAAAGAACAAACACTTGAACAAAAAGAAC
AAAGTATTTCTGATAGAGCGAAAAACCTTGATGCGCGTGAAGAGCAATTAGAGGAAGTCGAAAGACAAAAAGAAGCAGAA
CTAGAGCGTATTGGTGCTCTGTCTCAGGCAGAAGCACGAGATATTATCTTGGCTCAGACAGAGGAAAACTTGACCAGGGA
GATTGCCAGTCGCATTCGCGAAGCTGAGCAAGAGGTCAAGGAACGTTCTGACAAAATGGCCAAGGACATCTTGGTTCAAG
CTATGCAACGTATCGCTGGTGAATATGTAGCGGAGTCAACAAACTCAACAGTTCATCTGCCAGACGATACTATGAAGGGA
CGCATTATTGGTCGTGAAGGTCGTAACATTCGTACCTTTGAAAGTTTGACAGGGGTCGATGTGATTATCGACGATACACC
AGAAGTGGTGACCTTGTCAGGATTTGATCCGATTCGTCGTGAGATTGCCCGTATGACTATGGAAATGTTGCTCAAAGATG
GTCGTATACATCCAGCTCGTATCGAAGAGTTGGTTGAGAAAAACCGTCAAGAGATTGACAATAAGATTCGTGAATACGGT
GAGGCTGCTGCCTATGAAATTGGTGCGCCAAACCTTCATCCAGACTTGATGAAGATTATGGGACGTTTGCAGTTCCGTAC
TTCATATGGACAAAATGTTTTGCGCCATTCGATTGAGGTTGCTAAGTTGGCTGGTATCATGGCGAGCGAACTTGGTGAAA
ATGCGGCTCTTGCCCGTCGTGCTGGATTCCTTCACGATATCGGGAAAGCCATTGACCATGAGGTTGAAGGTAGCCACGTT
GAAATCGGTATGGAATTGGCCCGTAAGTACAAGGAACCCCCAGTTGTGGTGAATACGATTGCTAGTCACCACGGAGATGT
TGAAGCTGAGAGCGTGATAGCAGTTATCGTCGCTGCAGCAGATGCCTTGAGCGCAGCCCGTCCAGGTGCTCGTAGTGAGT
CTCTTGAAAGCTACATCAAGCGTCTCCATGATTTGGAAGAAATTGCTAACGGCTTTGAAGGAGTGCAAACTAGCTTTGCC
CTTCAAGCAGGACGTGAAATTCGTATCATGGTCAATCCAGGAAAAATCAAGGACGACAAAGTCACAATCTTGGCTCACAA
AGTTCGTAAGAAAATTGAAAACAATCTCGATTATCCAGGAAATATCAAGGTAACCGTGATTCGCGAGCTTCGTGCAGTAG
ATTATGCTAAATAA

Upstream 100 bases:

>100_bases
CCAAAACATATTCTATTTTAGGTTTGTGAAAATCACTTTTTTATGGTAGAATGTAAAAGAATGTATGTCATTCGGAATAA
CAATAAAATGAGGTAAAAAC

Downstream 100 bases:

>100_bases
ATAAGAAAGAGCAGTTGAAAAATTACTGCTTTTTTGTTACACTAGATAGAAAGACTGTAAAGGATAATCTGGCTTTTTGC
CATTATTCTAGAGAAATGTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 537

Protein sequence:

>537_residues
MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQEATNLRGQAEREADLLINEAKRESKSLKKEALLEAK
EEARKYREEVDAEFKSERQELKQIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRIAGEYVAESTNSTVHLPDDTMKG
RIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFDPIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYG
EAAAYEIGAPNLHPDLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAIDHEVEGSHV
EIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGARSESLESYIKRLHDLEEIANGFEGVQTSFA
LQAGREIRIMVNPGKIKDDKVTILAHKVRKKIENNLDYPGNIKVTVIRELRAVDYAK

Sequences:

>Translated_537_residues
MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQEATNLRGQAEREADLLINEAKRESKSLKKEALLEAK
EEARKYREEVDAEFKSERQELKQIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRIAGEYVAESTNSTVHLPDDTMKG
RIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFDPIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYG
EAAAYEIGAPNLHPDLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAIDHEVEGSHV
EIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGARSESLESYIKRLHDLEEIANGFEGVQTSFA
LQAGREIRIMVNPGKIKDDKVTILAHKVRKKIENNLDYPGNIKVTVIRELRAVDYAK
>Mature_537_residues
MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQEATNLRGQAEREADLLINEAKRESKSLKKEALLEAK
EEARKYREEVDAEFKSERQELKQIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRIAGEYVAESTNSTVHLPDDTMKG
RIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFDPIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYG
EAAAYEIGAPNLHPDLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAIDHEVEGSHV
EIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGARSESLESYIKRLHDLEEIANGFEGVQTSFA
LQAGREIRIMVNPGKIKDDKVTILAHKVRKKIENNLDYPGNIKVTVIRELRAVDYAK

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA [H]

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675 [H]

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1 [H]

EC number: =3.1.4.16 [H]

Molecular weight: Translated: 60245; Mature: 60245

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQEATNLRGQAEREADLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHH
INEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELKQIESRLTERATSLDRKDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAELERIGALSQAEARDIILAQT
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEECC
EENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRIAGEYVAESTNSTVHLPDDTMKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
RIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFDPIRREIARMTMEMLLKDGRIHPAR
CEECCCCCCCCHHHHHCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHH
IEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHPDLMKIMGRLQFRTSYGQNVLRHSIEV
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKLAGIMASELGENAALARRAGFLHDIGKAIDHEVEGSHVEIGMELARKYKEPPVVVNTI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
ASHHGDVEAESVIAVIVAAADALSAARPGARSESLESYIKRLHDLEEIANGFEGVQTSFA
HHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQAGREIRIMVNPGKIKDDKVTILAHKVRKKIENNLDYPGNIKVTVIRELRAVDYAK
HHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCCCC
>Mature Secondary Structure
MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQEATNLRGQAEREADLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHH
INEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELKQIESRLTERATSLDRKDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAELERIGALSQAEARDIILAQT
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEECC
EENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRIAGEYVAESTNSTVHLPDDTMKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
RIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFDPIRREIARMTMEMLLKDGRIHPAR
CEECCCCCCCCHHHHHCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHH
IEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHPDLMKIMGRLQFRTSYGQNVLRHSIEV
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKLAGIMASELGENAALARRAGFLHDIGKAIDHEVEGSHVEIGMELARKYKEPPVVVNTI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
ASHHGDVEAESVIAVIVAAADALSAARPGARSESLESYIKRLHDLEEIANGFEGVQTSFA
HHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQAGREIRIMVNPGKIKDDKVTILAHKVRKKIENNLDYPGNIKVTVIRELRAVDYAK
HHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA