Click here to switch to the map view.

The map label for this gene is alr [H]

Identifier: 225861522

GI number: 225861522

Start: 1562244

End: 1563347

Strand: Reverse

Name: alr [H]

Synonym: SPT_1636

Alternate gene names: 225861522

Gene position: 1563347-1562244 (Counterclockwise)

Preceding gene: 225861523

Following gene: 225861521

Centisome position: 74.02

GC content: 46.38

Gene sequence:

>1104_bases
ATGAAAGCTAGTCCACATAGACCAACCAAGGTTCTGATTCATCTGGGAGCTATTCGACAAAATATTCAGCAAATGGGGGC
TCATATCCCTCAAGGAACGCTCAAGTGGGCTGTGGTCAAGGCCAATGCTTATGGCCATGGAGCTGTTGCCGTTGCCAAGG
CAATTCAAGATGATGTTGATGGCTTTTGCGTTTCCAATATCGATGAAGCCATTGAACTCAGACAAGCTGGACTCAGCAAG
CCAATCCTCATTTTAGGAGTTTCTGAAATCGAAGCTGTTGCTCTAGCTAAAGAATATGACTTCACCTTGACAGTGGCTGG
ACTGGAGTGGATTCAAGCACTCTTAGATAAGGAAGTGGACCTAACTGGATTGACAGTCCACCTCAAGATTGATTCAGGGA
TGGGACGGATTGGTTTTAGAGAGGCCAGTGAGGTTGAGCAGGCTCAAGATTTGCTACAACAACACGGTGTTCGTGTTGAA
GGAATCTTTACCCACTTTGCTACTGCTGATGAGGAATCAGATGACTATTTTAATGCCCAGTTAGAACGGTTTAAAACTAT
TTTAGCTAGTATGAAGGAAGTTCCAGAGCTGGTTCATGCTAGCAATTCTGCAACGACTCTTTGGCATGTAGAGACTATTT
TCAATGCGGTTCGTATGGGAGATGCCATGTATGGCCTCAATCCAAGTGGAGCGGTCTTGGATTTGCCTTATGATTTGATA
CCGGCCTTGACCTTGGAGTCTGCTCTGGTTCATGTCAAGACAGTTCCAGCTGGAGCTTGCATGGGCTATGGAGCAACTTA
TCAAGCGGATAGCGAGCAAGTCATCGCGACCGTGCCAATCGGGTATGCAGATGGATGGACAAGAGACATGCAAAATTTCT
CTGTCTTGGTAGATGGCCAAGCTTGCCCAATTGTCGGCAGGGTTTCGATGGACCAAATCACTATTCGATTGCCTAAGCTT
TATCCGCTAGGAACCAAGGTAACCTTGATTGGCTCCAATGGGGATAAGGAAATCACTGCAACTCAGGTAGCGACCTACCG
CGTAACCATTAACTATGAGGTGGTTTGCCTCCTCAGCGACCGTATTCCGAGAGAATATTATTAG

Upstream 100 bases:

>100_bases
GCGCCTTATTTTAGTCAGGCACCATTTTCAGGAAAGATTTGGCTGTCTATCAGCCACACCGATCAGTTTGTGACAGCCAG
TGTCATTTTGGAGGAAAATC

Downstream 100 bases:

>100_bases
AAAAGAAAGGAGTGGAGCATGAATCTACATCAACCCTTGCATGTCTTGCCTGGTGTGGGACCAAAGTCAGCAGAAAAATA
CGCCAAACTAGGAATTGAAA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MKASPHRPTKVLIHLGAIRQNIQQMGAHIPQGTLKWAVVKANAYGHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSK
PILILGVSEIEAVALAKEYDFTLTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVRMGDAMYGLNPSGAVLDLPYDLI
PALTLESALVHVKTVPAGACMGYGATYQADSEQVIATVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKL
YPLGTKVTLIGSNGDKEITATQVATYRVTINYEVVCLLSDRIPREYY

Sequences:

>Translated_367_residues
MKASPHRPTKVLIHLGAIRQNIQQMGAHIPQGTLKWAVVKANAYGHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSK
PILILGVSEIEAVALAKEYDFTLTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVRMGDAMYGLNPSGAVLDLPYDLI
PALTLESALVHVKTVPAGACMGYGATYQADSEQVIATVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKL
YPLGTKVTLIGSNGDKEITATQVATYRVTINYEVVCLLSDRIPREYY
>Mature_367_residues
MKASPHRPTKVLIHLGAIRQNIQQMGAHIPQGTLKWAVVKANAYGHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSK
PILILGVSEIEAVALAKEYDFTLTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVRMGDAMYGLNPSGAVLDLPYDLI
PALTLESALVHVKTVPAGACMGYGATYQADSEQVIATVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKL
YPLGTKVTLIGSNGDKEITATQVATYRVTINYEVVCLLSDRIPREYY

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=365, Percent_Identity=36.1643835616438, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI1790487, Length=366, Percent_Identity=31.9672131147541, Blast_Score=148, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 40012; Mature: 40012

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKASPHRPTKVLIHLGAIRQNIQQMGAHIPQGTLKWAVVKANAYGHGAVAVAKAIQDDVD
CCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCC
GFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFTLTVAGLEWIQALLDKEVD
CHHHCCHHHHHHHHHCCCCCCEEEEEHHHHHEEEEEECCCEEEEEHHHHHHHHHHCCCCC
LTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVEGIFTHFATADEESDDYFNAQ
EEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHH
LERFKTILASMKEVPELVHASNSATTLWHVETIFNAVRMGDAMYGLNPSGAVLDLPYDLI
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCEEECCHHHH
PALTLESALVHVKTVPAGACMGYGATYQADSEQVIATVPIGYADGWTRDMQNFSVLVDGQ
HHHHHHHHEEEEEECCCCHHHCCCCEECCCCCCEEEEEECCCCCCCHHCCCCCEEEECCC
ACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNGDKEITATQVATYRVTINYEVVCLLSD
CCCEEECCCCCEEEEEECCEEECCEEEEEEECCCCCEEEEEEEEEEEEEEEEEEEEEEEC
RIPREYY
CCCCCCC
>Mature Secondary Structure
MKASPHRPTKVLIHLGAIRQNIQQMGAHIPQGTLKWAVVKANAYGHGAVAVAKAIQDDVD
CCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCC
GFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFTLTVAGLEWIQALLDKEVD
CHHHCCHHHHHHHHHCCCCCCEEEEEHHHHHEEEEEECCCEEEEEHHHHHHHHHHCCCCC
LTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVEGIFTHFATADEESDDYFNAQ
EEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHH
LERFKTILASMKEVPELVHASNSATTLWHVETIFNAVRMGDAMYGLNPSGAVLDLPYDLI
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCEEECCHHHH
PALTLESALVHVKTVPAGACMGYGATYQADSEQVIATVPIGYADGWTRDMQNFSVLVDGQ
HHHHHHHHEEEEEECCCCHHHCCCCEECCCCCCEEEEEECCCCCCCHHCCCCCEEEECCC
ACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNGDKEITATQVATYRVTINYEVVCLLSD
CCCEEECCCCCEEEEEECCEEECCEEEEEEECCCCCEEEEEEEEEEEEEEEEEEEEEEEC
RIPREYY
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA