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The map label for this gene is metA [H]

Identifier: 225861409

GI number: 225861409

Start: 1446015

End: 1446959

Strand: Reverse

Name: metA [H]

Synonym: SPT_1516

Alternate gene names: 225861409

Gene position: 1446959-1446015 (Counterclockwise)

Preceding gene: 225861411

Following gene: 225861408

Centisome position: 68.51

GC content: 42.01

Gene sequence:

>945_bases
ATGCCGATTCGAATTGATAAAAAATTGCCAGCTGTTGAGATTTTACGGACAGAGAACATCTTTGTTATGGATGATCAACG
TGCTGCCCACCAAGATATCCGTCCCTTGAAGATTTTAATCTTAAATCTTATGCCACAAAAAATGGTGACAGAGACTCAAT
TGTTGCGCCATTTGGCCAATACACCCCTGCAACTGGATATTGATTTCCTCTATATGGAGAGTCACCGTTCTAAAACAACT
CGTTCAGAGCACATGGAGACTTTTTATAAAACCTTTCCAGAAGTCAAGGATGAGTATTTTGATGGGATGATTATCACAGG
TGCTCCAGTTGAACATTTACCATTTGAGGAAGTGGACTACTGGGAGGAATTTACTCAGGTGCTTGAGTGGTCTAAGACCC
ATGTCTATTCGACCCTTCATATCTGTTGGGGAGCTCAGGCGGGACTCTATCTGCGTTATGGGGTGGAAAAATACCAGATG
GACAGTAAGTTATCGGGTATCTATCCTCAGGACACCTTAAAGGAAGGGCACCTTCTCTTTAGAGGCTTTGACGATAGCTA
CGTTTCCCCTCATTCTCGGCACACGGAGATTTCTAAGGAAGAGATTCTGAATAAGACCAATCTCGAGATTTTGTCAGAAG
GTCCTCAGGTTGGGGTTTCGATTTTGGCCAGTCGTGATTTGCGAGAAATTTATAGTTTTGGGCATTTGGAATATGACCGT
GATACCTTGGCAAAAGAGTATTTCAGAGATTGTGATGCAGGTTTAGCTCCTCATATTCCAGAAAATTATTTTAAGGATGA
TGATGTTAATCAGACCCCTTGTCTTTGTTGGTCTTCATCGGCAGCCCTCTTTTTCAGTAACTGGGTGAACTATGCGGTCT
ATCAGGAAACACCTTTTGACTGGAGAAAGATAGAAGATGATGCATCTGCATATGGGTATTTATAA

Upstream 100 bases:

>100_bases
CTTGAGTACGGCAAGGCAACGTTGACGCAGTTTGAAGAGATTTTCGAAGAGTTTCAAACATATGCAATGATTCCTGAAAG
AATACAGTTAGGAGAGGGTT

Downstream 100 bases:

>100_bases
GAGGAATTATGACATATTTAGACGCTTTTAAATCAGGGAACTTGGTTTTACCGAGTGCCCTGCTCTTGCATTTTAAGGAA
CTCTTTCCTTCTAGCGACGA

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLMPQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTT
RSEHMETFYKTFPEVKDEYFDGMIITGAPVEHLPFEEVDYWEEFTQVLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEILNKTNLEILSEGPQVGVSILASRDLREIYSFGHLEYDR
DTLAKEYFRDCDAGLAPHIPENYFKDDDVNQTPCLCWSSSAALFFSNWVNYAVYQETPFDWRKIEDDASAYGYL

Sequences:

>Translated_314_residues
MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLMPQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTT
RSEHMETFYKTFPEVKDEYFDGMIITGAPVEHLPFEEVDYWEEFTQVLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEILNKTNLEILSEGPQVGVSILASRDLREIYSFGHLEYDR
DTLAKEYFRDCDAGLAPHIPENYFKDDDVNQTPCLCWSSSAALFFSNWVNYAVYQETPFDWRKIEDDASAYGYL
>Mature_313_residues
PIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLMPQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTR
SEHMETFYKTFPEVKDEYFDGMIITGAPVEHLPFEEVDYWEEFTQVLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQMD
SKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEILNKTNLEILSEGPQVGVSILASRDLREIYSFGHLEYDRD
TLAKEYFRDCDAGLAPHIPENYFKDDDVNQTPCLCWSSSAALFFSNWVNYAVYQETPFDWRKIEDDASAYGYL

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=304, Percent_Identity=50, Blast_Score=318, Evalue=4e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 36750; Mature: 36619

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLMPQKMVTETQLLRHLAN
CCEECCCCCCCEEEEECCCEEEEECCHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHC
TPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDGMIITGAPVEHLPFEEVDY
CCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHH
WEEFTQVLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQMDSKLSGIYPQDTLKEGHLLF
HHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCHHHHHHHHHCCCCCHHHHCCCCEEE
RGFDDSYVSPHSRHTEISKEEILNKTNLEILSEGPQVGVSILASRDLREIYSFGHLEYDR
EECCCCCCCCCCCCCCCCHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCH
DTLAKEYFRDCDAGLAPHIPENYFKDDDVNQTPCLCWSSSAALFFSNWVNYAVYQETPFD
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHCEEEEECCCCC
WRKIEDDASAYGYL
HHHCCCCCHHCCCC
>Mature Secondary Structure 
PIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLMPQKMVTETQLLRHLAN
CEECCCCCCCEEEEECCCEEEEECCHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHC
TPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDGMIITGAPVEHLPFEEVDY
CCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHH
WEEFTQVLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQMDSKLSGIYPQDTLKEGHLLF
HHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCHHHHHHHHHCCCCCHHHHCCCCEEE
RGFDDSYVSPHSRHTEISKEEILNKTNLEILSEGPQVGVSILASRDLREIYSFGHLEYDR
EECCCCCCCCCCCCCCCCHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCH
DTLAKEYFRDCDAGLAPHIPENYFKDDDVNQTPCLCWSSSAALFFSNWVNYAVYQETPFD
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHCEEEEECCCCC
WRKIEDDASAYGYL
HHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA