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The map label for this gene is clpX [H]

Identifier: 225861402

GI number: 225861402

Start: 1439828

End: 1441036

Strand: Reverse

Name: clpX [H]

Synonym: SPT_1509

Alternate gene names: 225861402

Gene position: 1441036-1439828 (Counterclockwise)

Preceding gene: 225861403

Following gene: 225861401

Centisome position: 68.23

GC content: 44.5

Gene sequence:

>1209_bases
ATGATGGTTTATTGCTCATTTTGTGGCAAAAGCCAAGAAGAAGTACAAAAAATAATCGCTGGGAACAACGCCTTTATCTG
TAATGAATGTGTGGAGTTGGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAGTCTTGGCAGACTTGTCTGAGGTGC
CAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATCGGTCAAGATCGTGCCAAGCGTGCCTTGGCAGTGGCA
GTTTACAACCACTACAAACGCATCAATTTCCACGATACGCGTGAAGAGTCAGAAGATGTGGATTTGCAGAAGTCAAACAT
TTTGATGATTGGGCCAACTGGTTCAGGGAAAACTTTCCTTGCTCAGACCTTGGCTAAGAGCTTGAATGTGCCTTTTGCGA
TTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGACGTGGAAAATATCCTCCTTAAACTCTTGCAGGCT
GCTGACTTTAACATTGAGCGCGCAGAGCGTGGGATTATCTATGTGGATGAAATTGACAAGATTGCCAAGAAGAGCGAGAA
CGTGTCTATCACACGGGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGATTATCGAAGGAACAGTTGCTAGCG
TACCACCTCAAGGTGGACGCAAACATCCGCAACAAGAGATGATTCAAGTAGATACCAAGAATATCCTCTTCATTGTTGGT
GGTGCCTTTGATGGTATTGAAGAAATTGTCAAGCAACGTCTGGGTGAAAAAGTCATCGGATTTGGTCAAAACAATAAGGC
GATTGACGAAAACAGCTCTTACATGCAAGAAATCATCGCTGAAGATATTCAAAAATTTGGGATTATCCCTGAGTTGATTG
GACGCTTGCCTGTCTTTGCGGCTCTTGAGCAATTAACAGTCGATGACTTGGTTCGTATTTTGAAAGAACCAAGAAATGCC
TTGGTCAAACAGTACCAAACCTTGCTTTCTTATGATGATGTCGAGTTGGAATTTGACGACGAAGCCCTTCAGGAAATTGC
CAATAAGGCCATCGAACGGAAGACAGGGGCGCGTGGTCTTCGCTCGATTATCGAGGAAACCATGCTAGATGTCATGTTTG
AAGTACCGAGTCAGGAAAATGTGAAATTGGTCCGCATCACTAAAGAAGCTGTCGATGGAACGGATAAACCAATCCTAGAA
ACAGCCTAG

Upstream 100 bases:

>100_bases
GGTCAATAGTATCCATGCTTTTTACATGACCTTATTTTAGATAGAATGACAGTATAGAATAGAACGGAAGGAAATCATGC
CTACAACTAGGAATAATGAT

Downstream 100 bases:

>100_bases
AGGTGACTATGGAACTGAATACACACAATGCTGAAATCTTGCTCAGTGCGGCTAACAAGTCCCACTATCCGCAGGATGAA
CTACCAGAGATTGCCCTTGC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVA
VYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENILLKLLQA
ADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTKNILFIVG
GAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNA
LVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKEAVDGTDKPILE
TA

Sequences:

>Translated_402_residues
MMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVA
VYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENILLKLLQA
ADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTKNILFIVG
GAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNA
LVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKEAVDGTDKPILE
TA
>Mature_402_residues
MMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVA
VYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENILLKLLQA
ADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTKNILFIVG
GAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNA
LVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKEAVDGTDKPILE
TA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=324, Percent_Identity=48.7654320987654, Blast_Score=307, Evalue=1e-83,
Organism=Escherichia coli, GI1786642, Length=404, Percent_Identity=59.9009900990099, Blast_Score=485, Evalue=1e-138,
Organism=Escherichia coli, GI1790366, Length=211, Percent_Identity=33.175355450237, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982905, Length=320, Percent_Identity=45.3125, Blast_Score=280, Evalue=7e-76,
Organism=Caenorhabditis elegans, GI71982908, Length=320, Percent_Identity=45.3125, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI71988663, Length=403, Percent_Identity=37.2208436724566, Blast_Score=243, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI71988660, Length=253, Percent_Identity=39.1304347826087, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6319704, Length=430, Percent_Identity=39.5348837209302, Blast_Score=265, Evalue=7e-72,
Organism=Drosophila melanogaster, GI24648291, Length=320, Percent_Identity=48.75, Blast_Score=308, Evalue=3e-84,
Organism=Drosophila melanogaster, GI24648289, Length=320, Percent_Identity=48.75, Blast_Score=308, Evalue=4e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 44767; Mature: 44767

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELL
CEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
HILNHYVIGQDRAKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFL
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHH
AQTLAKSLNVPFAIADATALTEAGYVGEDVENILLKLLQAADFNIERAERGIIYVDEIDK
HHHHHHHCCCCEEEECHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHCCEEEHHHHHH
IAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTKNILFIVG
HHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEEC
GAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFA
CCHHHHHHHHHHHHCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCHHHH
ALEQLTVDDLVRILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHH
RSIIEETMLDVMFEVPSQENVKLVRITKEAVDGTDKPILETA
HHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHCCCCCCCCCCC
>Mature Secondary Structure
MMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELL
CEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
HILNHYVIGQDRAKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFL
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHH
AQTLAKSLNVPFAIADATALTEAGYVGEDVENILLKLLQAADFNIERAERGIIYVDEIDK
HHHHHHHCCCCEEEECHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHCCEEEHHHHHH
IAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTKNILFIVG
HHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEEC
GAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFA
CCHHHHHHHHHHHHCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCHHHH
ALEQLTVDDLVRILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHH
RSIIEETMLDVMFEVPSQENVKLVRITKEAVDGTDKPILETA
HHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA