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The map label for this gene is tehB [H]

Identifier: 225861136

GI number: 225861136

Start: 1169807

End: 1170667

Strand: Reverse

Name: tehB [H]

Synonym: SPT_1226

Alternate gene names: 225861136

Gene position: 1170667-1169807 (Counterclockwise)

Preceding gene: 225861137

Following gene: 225861135

Centisome position: 55.43

GC content: 42.16

Gene sequence:

>861_bases
ATGGAAAAATTAGTTGCCTATAAACGCATGCCTTTGTGGAATAAACAAACAATGCCTGAAGCTGTTCAGCAAAAGCACAA
TACAAAAGTTGGGACTTGGGGGAAAATTACTGTCTTGAAGGGAGCTCTCAAGTTTATTGAATTGACAGAAGAAGGGGAAG
TTCTAGCTGAACACCTCTTTGAAGCAGGGGCAGACAATCCAATGGCCCAGCCTCAAGCCTGGCACCGAGTGGAAGCTGCC
ACAGATGATGTGGAATGGTACTTGGAATTTTATTGTAAACCTGAGGATTATTTTGCTAAAAAATACAATACCAAACCTGT
TCATTCAGAGGTCCTAGAGGCCATGCAGACAGTGAAACAAGGGAAAGCTTTGGATTTGGGTTGTGGTCAGGGGCGTAATT
CTCTTTTTCTAGCCCAGCAAGATTTTGATGTGACGGCTGTAGATCAAAATGGACTGGCTCTTGAAATCTTGCAAAGCATT
GTGGAGCAGGAAGATTTGGACATACCTGTTGACCTTTACGATATCAATTCAGCTAGCATTGGACAAGAATATGATTTTAT
CGTTTCAACAGTTGTTCTCATGTTTCTACAAGCGGACCGCATTCCAGCTATTATTCAAAATATGCAGGAGAAAACCAGTG
TTGGTGGTTACAACCTTATCGTTTGTGCCATGGACACGGAGGACTATCCTTGCTCGGTTAACTTCCCATTCACCTTTAAA
GAAGGAGAACTGGCAGACTATTACAAGGATTGGGAATTGGTTAAGTACAATGAAAATCCAGGCCATTTGCATCGTCGCGA
TGAGAATGGCAATCGTATTCAACTACGCTTTGCGACCTTACTAGCTAAGAAAATCAAGTAA

Upstream 100 bases:

>100_bases
TGACTATGACAAACGGGAGTCTATCAAACGTCGTGAGCAAAATCGAGATATCGCGCGTGTGATGAAAGCTGTTAATCAGC
GATAAAAAGAGGAATTGAAA

Downstream 100 bases:

>100_bases
ACACACATGAAGATTAGGAATTTTCCTGATCTTTTTTCTTTTTTACGAATGATATAGAAAAGGAGGGAATTCATGTTTGT
TGCGAGAGATGCTAGGGGAG

Product: tellurite resistance protein TehB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALKFIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAA
TDDVEWYLEFYCKPEDYFAKKYNTKPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
VEQEDLDIPVDLYDINSASIGQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYNLIVCAMDTEDYPCSVNFPFTFK
EGELADYYKDWELVKYNENPGHLHRRDENGNRIQLRFATLLAKKIK

Sequences:

>Translated_286_residues
MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALKFIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAA
TDDVEWYLEFYCKPEDYFAKKYNTKPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
VEQEDLDIPVDLYDINSASIGQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYNLIVCAMDTEDYPCSVNFPFTFK
EGELADYYKDWELVKYNENPGHLHRRDENGNRIQLRFATLLAKKIK
>Mature_286_residues
MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALKFIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAA
TDDVEWYLEFYCKPEDYFAKKYNTKPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
VEQEDLDIPVDLYDINSASIGQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYNLIVCAMDTEDYPCSVNFPFTFK
EGELADYYKDWELVKYNENPGHLHRRDENGNRIQLRFATLLAKKIK

Specific function: Probable S-adenosyl-L-methionine dependent methyltransferase that is responsible for tellurite resistance when present in high copy number. Binds tellurite and S-adenosyl- L-methionine [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm. Note=Probably a peripheral membrane protein that interacts with TehA (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TehB family [H]

Homologues:

Organism=Escherichia coli, GI1787700, Length=193, Percent_Identity=58.0310880829015, Blast_Score=235, Evalue=3e-63,
Organism=Escherichia coli, GI1788098, Length=113, Percent_Identity=28.3185840707965, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015392
- InterPro:   IPR014710
- InterPro:   IPR004537
- InterPro:   IPR014431
- InterPro:   IPR015985 [H]

Pfam domain/function: PF09313 DUF1971; PF03848 TehB [H]

EC number: NA

Molecular weight: Translated: 32667; Mature: 32667

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALKFIELTEEGEVLAEHLF
CCCHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCEEHHHHHHHHHHEEECCCHHHHHHHHH
EAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKYNTKPVHSEVLEAMQTVKQ
HCCCCCCCCCCHHHHHHHHCCCHHEEEEHEEECCHHHHHHHCCCCCHHHHHHHHHHHHHC
GKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSIVEQEDLDIPVDLYDINSASI
CCEEECCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCC
GQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYNLIVCAMDTEDYPCSVNFPFTFK
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEECCCEEEC
EGELADYYKDWELVKYNENPGHLHRRDENGNRIQLRFATLLAKKIK
CCCHHHHHCCCEEEEECCCCCCCEECCCCCCEEEEEHHHHHHHHCC
>Mature Secondary Structure
MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALKFIELTEEGEVLAEHLF
CCCHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCEEHHHHHHHHHHEEECCCHHHHHHHHH
EAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKYNTKPVHSEVLEAMQTVKQ
HCCCCCCCCCCHHHHHHHHCCCHHEEEEHEEECCHHHHHHHCCCCCHHHHHHHHHHHHHC
GKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSIVEQEDLDIPVDLYDINSASI
CCEEECCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCC
GQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYNLIVCAMDTEDYPCSVNFPFTFK
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEECCCEEEC
EGELADYYKDWELVKYNENPGHLHRRDENGNRIQLRFATLLAKKIK
CCCHHHHHCCCEEEEECCCCCCCEECCCCCCEEEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]