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The map label for this gene is yfnA [H]

Identifier: 225861114

GI number: 225861114

Start: 1148628

End: 1150019

Strand: Reverse

Name: yfnA [H]

Synonym: SPT_1200

Alternate gene names: 225861114

Gene position: 1150019-1148628 (Counterclockwise)

Preceding gene: 225861115

Following gene: 225861113

Centisome position: 54.45

GC content: 40.95

Gene sequence:

>1392_bases
ATGAATATATTTAGAACAAAGAATGTTAGTTTAGATAAAACAGAGATGCATAGGCATTTGAAGTTATGGGATTTGATTTT
GCTGGGTATCGGAGCCATGGTAGGGACAGGCGTCTTTACAATCACAGGTACTGCAGCTGCAACACTTGCTGGCCCAGCCC
TAGTGATTTCAATCGTTATTTCTGCCTTGTGTGTGGGATTATCAGCCCTCTTTTTTGCAGAATTTGCCTCGCGAGTACCC
GCTACAGGAGGTGCCTATAGTTACCTCTATGCTATCTTAGGAGAATTCCCTGCCTGGTTGGCTGGTTGGTTAACCATGAT
GGAGTTCATGACAGCCATATCAGGCGTAGCTTCGGGTTGGGCAGCTTATTTTAAAGGCTTGCTCTCTCAATACGGGATAG
CCCTTCCTCAGGCTTTAAATGGTACCTTTAATCCTCAAGCAGGGATATTTGTTGATTTATTGCCTATTCTTGTCTTGGTC
TTGGTGACTTCGCTTGTTTTACTAAATGCCAAGGCAGCCTTACGCTTTAATTCGATTCTAGTTATTTTGAAATTTTCCGC
TTTAGCTCTCTTTGTTTTAGTAGGAATTTGGAATATTAAGTTTGATAATTGGAGCAATTTTGCTCCTTACGGTTTTGGAC
AAATCTATGGAGCTAGTACTGGTATTATGGCTGGTGCGTCTTTGATGTTCTTCGGTTTTTTGGGATTTGAATCCATCTCT
ATGGCTGTAGATGAAGTCAAGACTCCTCAAAAAAATATTCCTAGAGGGATTGTCTTATCGCTTTCTATCGTAACCATTCT
CTATGCCTTGGTGACCCTTGTTTTGACTGGTGTGGTTCACTATAGTCATTTAAATGTCGATGATGCCGTTGCCTTTGCCC
TTCGTAGTGTTGGGATTAGTTGGGCAGCCAACTATGTGTCATTAGTGGCTATCTTGACCTTGATTACAGTTTGTATTTCG
ATGACCTATGCCCTATCGCGTATGATTTACAGTTTAGCACGTGACGGCTTAGTGCCTGCTGCCTTTAAGGAACTGACGAA
GACTAGCAAGATACCAAAGAATGCTACTATCTTGACAGGTCTAGCTTCAGCAGTAGCAGCAGGAATGTTCCCACTAGCCA
GTATTGCAGCCTTTTTAAATATTTGTACCTTAGCCTACTTGATCATGTTGGCTTATGGTCTGATTCGCTTACGGAAAGAA
AAAGGAATGCCCAAAGCTGGGGAATTTAAAACACCATTGGTACCTCTGTTACCAATTTTATCGATCATCATTTGTTTATC
CTTCATGTTACAGTATAATATGAATACCTGGATTGCTTTCCTAGTTGCGTTGTTAGTAGGAAGTATTATTTACTTCACTT
ATGGCTATAAGCATTCTACCATAGAAGAATAA

Upstream 100 bases:

>100_bases
TTACGGTAGTCAGATTTTTTTAGAAAAACATTTTATAAATATTCACATATCTCCTATATTTATGGTAAAATAGAATTATC
AGTTTATTTTGGAGTCAAAG

Downstream 100 bases:

>100_bases
AGTGAAAGTCTATTGAGTTGTTGACACTCAGCAGATTTTTATATGTGAAAGAAATTTCAAATTTTTTCTAAAAATATCTT
GACAGATTAAATTTTCAGGA

Product: amino acid permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGTAAATLAGPALVISIVISALCVGLSALFFAEFASRVP
ATGGAYSYLYAILGEFPAWLAGWLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGIFVDLLPILVLV
LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGASTGIMAGASLMFFGFLGFESIS
MAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLTGVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCIS
MTYALSRMIYSLARDGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAYGLIRLRKE
KGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSIIYFTYGYKHSTIEE

Sequences:

>Translated_463_residues
MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGTAAATLAGPALVISIVISALCVGLSALFFAEFASRVP
ATGGAYSYLYAILGEFPAWLAGWLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGIFVDLLPILVLV
LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGASTGIMAGASLMFFGFLGFESIS
MAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLTGVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCIS
MTYALSRMIYSLARDGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAYGLIRLRKE
KGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSIIYFTYGYKHSTIEE
>Mature_463_residues
MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGTAAATLAGPALVISIVISALCVGLSALFFAEFASRVP
ATGGAYSYLYAILGEFPAWLAGWLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGIFVDLLPILVLV
LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGASTGIMAGASLMFFGFLGFESIS
MAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLTGVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCIS
MTYALSRMIYSLARDGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAYGLIRLRKE
KGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSIIYFTYGYKHSTIEE

Specific function: Transporter For The Intake Of S-Methylmethionine. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI110347453, Length=406, Percent_Identity=32.0197044334975, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI4507047, Length=437, Percent_Identity=29.5194508009153, Blast_Score=172, Evalue=8e-43,
Organism=Homo sapiens, GI258614003, Length=447, Percent_Identity=30.6487695749441, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI258614005, Length=447, Percent_Identity=30.6487695749441, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI258645169, Length=449, Percent_Identity=31.4031180400891, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI181337167, Length=389, Percent_Identity=30.0771208226221, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI114326544, Length=423, Percent_Identity=27.4231678486998, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI114326550, Length=423, Percent_Identity=27.4231678486998, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI7657683, Length=414, Percent_Identity=24.8792270531401, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI33286428, Length=391, Percent_Identity=24.8081841432225, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI115648063, Length=344, Percent_Identity=22.9651162790698, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI115648022, Length=344, Percent_Identity=22.9651162790698, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI187423910, Length=459, Percent_Identity=22.2222222222222, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI7657591, Length=459, Percent_Identity=22.2222222222222, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI71979932, Length=430, Percent_Identity=24.4186046511628, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI87081708, Length=457, Percent_Identity=22.5382932166302, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI87082250, Length=361, Percent_Identity=25.4847645429363, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788480, Length=468, Percent_Identity=23.5042735042735, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1786302, Length=445, Percent_Identity=22.0224719101124, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789017, Length=412, Percent_Identity=24.5145631067961, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786694, Length=285, Percent_Identity=27.0175438596491, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1790653, Length=448, Percent_Identity=24.1071428571429, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1786789, Length=447, Percent_Identity=22.8187919463087, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87081869, Length=435, Percent_Identity=20.2298850574713, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=418, Percent_Identity=31.5789473684211, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17533459, Length=413, Percent_Identity=31.9612590799031, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17531343, Length=483, Percent_Identity=28.9855072463768, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17568033, Length=419, Percent_Identity=26.2529832935561, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17540018, Length=417, Percent_Identity=25.1798561151079, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI32566699, Length=341, Percent_Identity=24.633431085044, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17537453, Length=422, Percent_Identity=21.8009478672986, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71982612, Length=443, Percent_Identity=23.0248306997743, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71982608, Length=443, Percent_Identity=23.0248306997743, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24667468, Length=439, Percent_Identity=32.5740318906606, Blast_Score=229, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24668806, Length=424, Percent_Identity=31.3679245283019, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI21356285, Length=424, Percent_Identity=31.3679245283019, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI24668802, Length=424, Percent_Identity=31.3679245283019, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI221512776, Length=416, Percent_Identity=30.0480769230769, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24666159, Length=416, Percent_Identity=30.0480769230769, Blast_Score=192, Evalue=4e-49,
Organism=Drosophila melanogaster, GI281366235, Length=412, Percent_Identity=31.5533980582524, Blast_Score=165, Evalue=6e-41,
Organism=Drosophila melanogaster, GI116007820, Length=412, Percent_Identity=31.5533980582524, Blast_Score=165, Evalue=6e-41,
Organism=Drosophila melanogaster, GI161077963, Length=418, Percent_Identity=30.3827751196172, Blast_Score=165, Evalue=7e-41,
Organism=Drosophila melanogaster, GI116007818, Length=412, Percent_Identity=31.5533980582524, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI85725152, Length=412, Percent_Identity=31.5533980582524, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI221331183, Length=424, Percent_Identity=22.4056603773585, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI17647653, Length=424, Percent_Identity=22.4056603773585, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24664379, Length=424, Percent_Identity=22.4056603773585, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI21357367, Length=363, Percent_Identity=23.6914600550964, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45550968, Length=355, Percent_Identity=24.5070422535211, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19921172, Length=355, Percent_Identity=24.5070422535211, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24651635, Length=346, Percent_Identity=22.8323699421965, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24651633, Length=346, Percent_Identity=22.8323699421965, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49879; Mature: 49879

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGTAAATLAGPALVISIVI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHH
SALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAGWLTMMEFMTAISGVASGW
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAYFKGLLSQYGIALPQALNGTFNPQAGIFVDLLPILVLVLVTSLVLLNAKAALRFNSIL
HHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGASTGIMAGASLMFFGFLGFESIS
HHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
MAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLTGVVHYSHLNVDDAVAFALRSVGIS
HHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
WAANYVSLVAILTLITVCISMTYALSRMIYSLARDGLVPAAFKELTKTSKIPKNATILTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHH
LASAVAAGMFPLASIAAFLNICTLAYLIMLAYGLIRLRKEKGMPKAGEFKTPLVPLLPIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
SIIICLSFMLQYNMNTWIAFLVALLVGSIIYFTYGYKHSTIEE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGTAAATLAGPALVISIVI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHH
SALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAGWLTMMEFMTAISGVASGW
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAYFKGLLSQYGIALPQALNGTFNPQAGIFVDLLPILVLVLVTSLVLLNAKAALRFNSIL
HHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGASTGIMAGASLMFFGFLGFESIS
HHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
MAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLTGVVHYSHLNVDDAVAFALRSVGIS
HHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
WAANYVSLVAILTLITVCISMTYALSRMIYSLARDGLVPAAFKELTKTSKIPKNATILTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHH
LASAVAAGMFPLASIAAFLNICTLAYLIMLAYGLIRLRKEKGMPKAGEFKTPLVPLLPIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
SIIICLSFMLQYNMNTWIAFLVALLVGSIIYFTYGYKHSTIEE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]