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The map label for this gene is adcA [H]

Identifier: 225861113

GI number: 225861113

Start: 1147568

End: 1148485

Strand: Reverse

Name: adcA [H]

Synonym: SPT_1199

Alternate gene names: 225861113

Gene position: 1148485-1147568 (Counterclockwise)

Preceding gene: 225861114

Following gene: 225861112

Centisome position: 54.38

GC content: 38.45

Gene sequence:

>918_bases
ATGAAGAAACAAAATTTATTTTTAGTCCTGTTAAGTGTCTTTCTTTTGTGCTTGGGGGCTTGTGGTCAAAAGGAAAGTCA
GACAGGAAAGGGGATGAAAATTGTGACCAGTTTTTATCCTATCTACGCTATGGTTAAGGAAGTATCTGGTGACTTGAATG
ATGTTCGGATGATTCAGTCAAGTAGTGGTATTCACTCCTTTGAACCTTCGGCAAATGATATCGCAGCCATCTATGATGCA
GATGTCTTTGTTTACCATTCTCATACACTCGAATCTTGGGCAGGAAGTCTGGATCCAAATCTAAAAAAATCCAAAGTGAA
GGTCTTAGAGGCTTCTGAGGGAATGACCTTGGAACGTGTCCCTGGACTAGAGGATGTGGAAGCAGGGGATGGAGTTGATG
AAAAAACGCTCTATGACCCTCACACATGGCTAGATCCTGAAAAAGCTGGAGAAGAAGCCCAAATTATCGCTGATAAACTT
TCAGAGGTGGATAGTGAGCATAAAGAGACTTATCAAAAAAATGCGCAAGCCTTTATCAAAAAAGCTCAGGAATTGACTAA
GAAATTCCAACCAAAATTTGAAAAAGCGACTCAGAAAACATTTGTAACACAACATACAGCCTTTTCTTATCTAGCGAAGA
GATTTGGGCTTAATCAACTTGGTATTGCAGGTATCTCTCCTGAACAAGAACCAAGTCCACGACAACTAACAGAAATTCAG
GAATTTGTTAAGACCTATAAGGTTAAAACGATTTTTACAGAAAGTAATGCTTCTTCAAAAGTAGCTGAAACTCTTGTCAA
ATCAACAGGTGTGGGTCTTAAAACTCTGAATCCTTTAGAGTCAGACCCACAAAATGACAAGACCTATTTAGAAAATCTTG
AAGAAAATATGAGTATTCTAGCAGAAGAATTAAAGTGA

Upstream 100 bases:

>100_bases
ATGTGAAAGAAATTTCAAATTTTTTCTAAAAATATCTTGACAGATTAAATTTTCAGGAGTAGAATATTTACTAGTTAATT
AAATGGTTAAGGAGTTGTTC

Downstream 100 bases:

>100_bases
GGAAAGAATGAAAATTAATAAAAAATATCTAGCAGGTTCAGTGGCAGTCCTTGCCCTAAGTGTTTGTTCCTATGAGCTTG
GACGTTACCAAGCTGGTCAG

Product: zinc-binding lipoprotein AdcA

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAMVKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDA
DVFVYHSHTLESWAGSLDPNLKKSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLNQLGIAGISPEQEPSPRQLTEIQ
EFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTLNPLESDPQNDKTYLENLEENMSILAEELK

Sequences:

>Translated_305_residues
MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAMVKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDA
DVFVYHSHTLESWAGSLDPNLKKSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLNQLGIAGISPEQEPSPRQLTEIQ
EFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTLNPLESDPQNDKTYLENLEENMSILAEELK
>Mature_305_residues
MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAMVKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDA
DVFVYHSHTLESWAGSLDPNLKKSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLNQLGIAGISPEQEPSPRQLTEIQ
EFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTLNPLESDPQNDKTYLENLEENMSILAEELK

Specific function: Part of the ATP-driven transport system AdcABC for zinc. Required for transformability [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=288, Percent_Identity=23.2638888888889, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR012674
- InterPro:   IPR011038
- InterPro:   IPR006128
- InterPro:   IPR015304 [H]

Pfam domain/function: PF01297 SBP_bac_9; PF09223 YodA [H]

EC number: NA

Molecular weight: Translated: 33952; Mature: 33952

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAMVKEVSGDLNDVRMIQS
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
SSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLKKSKVKVLEASEGMTLERV
CCCCCCCCCCCCCEEEEEECEEEEEECCHHHHHCCCCCCCCCHHHHHEEECCCCCCHHHC
PGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKLSEVDSEHKETYQKNAQAFIK
CCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLNQLGIAGISPEQEPSPRQLTEIQ
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
EFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTLNPLESDPQNDKTYLENLEENMSIL
HHHHHHHHHEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AEELK
HHHCC
>Mature Secondary Structure
MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAMVKEVSGDLNDVRMIQS
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
SSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLKKSKVKVLEASEGMTLERV
CCCCCCCCCCCCCEEEEEECEEEEEECCHHHHHCCCCCCCCCHHHHHEEECCCCCCHHHC
PGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKLSEVDSEHKETYQKNAQAFIK
CCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLNQLGIAGISPEQEPSPRQLTEIQ
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
EFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTLNPLESDPQNDKTYLENLEENMSIL
HHHHHHHHHEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AEELK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]