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The map label for this gene is rnhC [H]

Identifier: 225860427

GI number: 225860427

Start: 408237

End: 409118

Strand: Reverse

Name: rnhC [H]

Synonym: SPT_0441

Alternate gene names: 225860427

Gene position: 409118-408237 (Counterclockwise)

Preceding gene: 225860434

Following gene: 225860426

Centisome position: 19.37

GC content: 44.67

Gene sequence:

>882_bases
ATGGCAAGTATCACACTCACACCAAGCGAAAAGGATATTCAGGCTTTTCTTGAACACTATCAAACCAGTCTGGCTCCTAG
CAAGAATCCCTATATCCGCTACTTTTTGAAACTACCTCAAGCAACGGTTTCTATCTATACTTCTGGAAAAATCTTGCTTC
AGGGTGAAGGGGCTGAAAAATACGCCAGTTTCTTTGGCTATCAAGCTGTAGAGCAAACCAGCGGACAAAATCTTCCTTTA
ATTGGGACAGATGAGGTGGGAAATGGTTCCTACTTTGGTGGGCTTGCAGTTGTGGCTGCCTTTGTCACACCTGACCAGCA
CGACTTTTTACGAAAACTCGGTGTGGGGGATTCTAAGACTCTGACCGACCAAAAGATCCGTCAGATTGCTCCTATTCTCA
AGGAAAAAATCCAGCACCAGGCACTCCTTCTCTCACCCAGCAAGTACAACGAGGTCATCGGAAACCGCTACAATGCTGTT
TCGGTTAAGGTTGCCCTCCATAATCAGGCTATCTATCTCCTCCTTCAAAAAGGTGTTCAGCCTGAGAAAATTGTGATTGA
TGCCTTTACCAGTGCTAAAAATTATGACAAGTACTTGGCACAAGAGACCAATCGTTTCAGCAATCCTATCAGCTTAGAAG
AAAAGGCTGAGGGCAAATACTTGGCTGTCGCAGTTTCTTCTGTCATTGCGCGTGATCTCTTTCTGGAAAATCTTGAAAAT
TTGGGACGAGAACTGGGTTATCAGCTTCCAAGTGGAGCTGGAACGGCTTCTGACAAGGTGGCTAGCCAGATTTTGCAAGC
CTATGGTATGCAGGGACTCAACTTCTGCGCCAAATTGCACTTTAAAAACACTGAAAAAGCGAAAAAACGCTTAGAAAGGT
AA

Upstream 100 bases:

>100_bases
TTTAGATTTGCCATAAAATTCACCTCACGATATTATACCAAAATTCGCTAATTTTGTCAGTTTTTACAAATTTTACTGCT
TTTGTGGTACAATAGAAACT

Downstream 100 bases:

>100_bases
GTTATGAATTCATTTAAAAATTTCTTGAAAGAGTGGGGACTGTTCCTCCTAATTCTGTCATTACTAGCTTTAAGTCGTAT
CTTTTTTTGGAGCAATGTTC

Product: ribonuclease HIII

Products: NA

Alternate protein names: RNase HIII [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVSIYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPL
IGTDEVGNGSYFGGLAVVAAFVTPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGNRYNAV
SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEGKYLAVAVSSVIARDLFLENLEN
LGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFCAKLHFKNTEKAKKRLER

Sequences:

>Translated_293_residues
MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVSIYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPL
IGTDEVGNGSYFGGLAVVAAFVTPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGNRYNAV
SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEGKYLAVAVSSVIARDLFLENLEN
LGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFCAKLHFKNTEKAKKRLER
>Mature_292_residues
ASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVSIYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLI
GTDEVGNGSYFGGLAVVAAFVTPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGNRYNAVS
VKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEGKYLAVAVSSVIARDLFLENLENL
GRELGYQLPSGAGTASDKVASQILQAYGMQGLNFCAKLHFKNTEKAKKRLER

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG1039

COG function: function code L; Ribonuclease HIII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family. RnhC subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001352
- InterPro:   IPR004641
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 32357; Mature: 32226

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVSIYTSGKILLQGEGAEK
CCEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEECCEEEEECCCHHH
YASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFVTPDQHDFLRKLGVGDSKT
HHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
LTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGNRYNAVSVKVALHNQAIYLLLQKGVQ
HHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHCCCCCEEEEEEEECCHHHHHHHHCCCC
PEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEGKYLAVAVSSVIARDLFLENLEN
CCEEEEECHHCHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEHHHHHHHHHHHHHHHHHHH
LGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFCAKLHFKNTEKAKKRLER
HHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure 
ASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVSIYTSGKILLQGEGAEK
CEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEECCEEEEECCCHHH
YASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFVTPDQHDFLRKLGVGDSKT
HHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
LTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGNRYNAVSVKVALHNQAIYLLLQKGVQ
HHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHCCCCCEEEEEEEECCHHHHHHHHCCCC
PEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEGKYLAVAVSSVIARDLFLENLEN
CCEEEEECHHCHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEHHHHHHHHHHHHHHHHHHH
LGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFCAKLHFKNTEKAKKRLER
HHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11442348 [H]