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The map label for this gene is recU [H]

Identifier: 225860400

GI number: 225860400

Start: 382632

End: 383228

Strand: Reverse

Name: recU [H]

Synonym: SPT_0413

Alternate gene names: 225860400

Gene position: 383228-382632 (Counterclockwise)

Preceding gene: 225860409

Following gene: 225860399

Centisome position: 18.14

GC content: 38.19

Gene sequence:

>597_bases
ATGGTCAACTATCCACATAAACTTTCATCACAAAAAAGACAACCATCTCTTTCTCAACCCAAAAATTTCGCAAATCGAGG
AATGTCTTTTGAAAAGATGATCAATGCTACCAACGACTACTATTTGTCTCAGGGCTTGGCTGTTATACACAAGAAACCAA
CTCCTATTCAAATCGTACGAGTGGACTATCCACAACGAAGTCGTGCCAAGATTGTTGAAGCCTATTTTCGACAAGCTTCA
ACGACGGACTATTCTGGCGTTTATAATGGATATTACATCGACTTTGAAGCCAAGGAAACAAAACAAAAACGTGCGATTCC
GATGAAAAATTTCCATCCACATCAGATTCAGCATATGGAACAAATCCTTGCTCAACAAGGAATCTGCTTTGTCCTTCTTC
ACTTTTCTTCTCAGCAAGAAACCTACTTATTACCGGCATATGATTTGATTCGCTTCTATCATCAAGATAAGGGGCAAAAA
TCAATGCCACTTGGATATATTCGAGAATATGGATATGAAATCAAGGCTGGTGCCTTCCCTCAAATTCCCTATCTCAATGT
TATCAAAGAACATTTATTAGGTGGTAAAACAAGATGA

Upstream 100 bases:

>100_bases
AAGCAGAATAGCCCAAAACCAAAGCTGTAGCCATTTTTAACCCTTTCTGTGCAAATTTATGGTATAATAGAGTGATGTTA
TTGTACCAATAAGGAGAATT

Downstream 100 bases:

>100_bases
ACAAACAAACTATCCTGCGAATAGCTAAGTATGTGAGTATCTGCTTCTTAACTTTATTTATCACAGCAGTTATGCTGGGA
GGAGGCATATTTCTCTATTA

Product: Holliday junction-specific endonuclease

Products: NA

Alternate protein names: Recombination protein U homolog [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MVNYPHKLSSQKRQPSLSQPKNFANRGMSFEKMINATNDYYLSQGLAVIHKKPTPIQIVRVDYPQRSRAKIVEAYFRQAS
TTDYSGVYNGYYIDFEAKETKQKRAIPMKNFHPHQIQHMEQILAQQGICFVLLHFSSQQETYLLPAYDLIRFYHQDKGQK
SMPLGYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR

Sequences:

>Translated_198_residues
MVNYPHKLSSQKRQPSLSQPKNFANRGMSFEKMINATNDYYLSQGLAVIHKKPTPIQIVRVDYPQRSRAKIVEAYFRQAS
TTDYSGVYNGYYIDFEAKETKQKRAIPMKNFHPHQIQHMEQILAQQGICFVLLHFSSQQETYLLPAYDLIRFYHQDKGQK
SMPLGYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR
>Mature_198_residues
MVNYPHKLSSQKRQPSLSQPKNFANRGMSFEKMINATNDYYLSQGLAVIHKKPTPIQIVRVDYPQRSRAKIVEAYFRQAS
TTDYSGVYNGYYIDFEAKETKQKRAIPMKNFHPHQIQHMEQILAQQGICFVLLHFSSQQETYLLPAYDLIRFYHQDKGQK
SMPLGYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR

Specific function: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair

COG id: COG3331

COG function: function code R; Penicillin-binding protein-related factor A, putative recombinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recU family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004612
- InterPro:   IPR011335 [H]

Pfam domain/function: PF03838 RecU [H]

EC number: NA

Molecular weight: Translated: 23099; Mature: 23099

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNYPHKLSSQKRQPSLSQPKNFANRGMSFEKMINATNDYYLSQGLAVIHKKPTPIQIVR
CCCCCCHHHHHHCCCCCCCCHHHHHCCCCHHHHHCCCCHHHHHCCEEEEECCCCCEEEEE
VDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEAKETKQKRAIPMKNFHPHQIQHME
ECCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHCCCCCCCCHHHHHHHH
QILAQQGICFVLLHFSSQQETYLLPAYDLIRFYHQDKGQKSMPLGYIREYGYEIKAGAFP
HHHHHCCCEEEEEEECCCCCEEECHHHHHHHHHHHCCCCCCCCHHHHHHCCCEECCCCCC
QIPYLNVIKEHLLGGKTR
CCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVNYPHKLSSQKRQPSLSQPKNFANRGMSFEKMINATNDYYLSQGLAVIHKKPTPIQIVR
CCCCCCHHHHHHCCCCCCCCHHHHHCCCCHHHHHCCCCHHHHHCCEEEEECCCCCEEEEE
VDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEAKETKQKRAIPMKNFHPHQIQHME
ECCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHCCCCCCCCHHHHHHHH
QILAQQGICFVLLHFSSQQETYLLPAYDLIRFYHQDKGQKSMPLGYIREYGYEIKAGAFP
HHHHHCCCEEEEEEECCCCCEEECHHHHHHHHHHHCCCCCCCCHHHHHHCCCEECCCCCC
QIPYLNVIKEHLLGGKTR
CCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA