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The map label for this gene is luxS [H]

Identifier: 225860378

GI number: 225860378

Start: 351196

End: 351678

Strand: Reverse

Name: luxS [H]

Synonym: SPT_0389

Alternate gene names: 225860378

Gene position: 351678-351196 (Counterclockwise)

Preceding gene: 225860379

Following gene: 225860372

Centisome position: 16.65

GC content: 45.76

Gene sequence:

>483_bases
ATGTCAAAAGAAGTTATTGTCGAAAGTTTTGAACTTGACCACACCATTGTCAAAGCACCCTATGTTCGCTTGATTGGGGA
AGAAACAGGACCAAAAGGAGACATCATCTCCAATTATGATATTCGCTTGGTGCAACCAAACGAAGACTCTATCCCTACCG
CCGGCCTTCACACTATCGAGCACCTCTTAGCCAAACTCATCCGTACCCGCATTGACGGCATGATTGACTGTTCACCATTT
GGTTGCCGCACAGGCTTCCACATGATTATGTGGGGACGTCACACCAGTGCTAAAATCGCAGCTGTTATCAAGGATTCGCT
CAAGGAAATCGCTGAAACTACTACTTGGGAAGATGTCCCAGGGACAACCATCGAATCTTGCGGAAACTACAAGGACCACA
GCCTCTTCTCTGCTAAAGAATGGGCAAAACTCATCTTGGAACAAGGGATTTCAGATGATGCCTTTGAACGTCATGTGATT
TAA

Upstream 100 bases:

>100_bases
AAGTAAAGATTTCAACCTCTCCAGCCTCGGAGAGGTTTTCTCTCTGTCTCAGGAGCAACCTTTATGATATAATGAGAGAA
GAAAACTGAAAGGATTTACC

Downstream 100 bases:

>100_bases
AATCGAGTAGGGGATAATCTCTAGCCCCTCTCACACCACCGTACGTGCTGTTCGGCATACGGCGGTTCAACTAACTTTTA
ACGCATGTCGTTCAAGGTAA

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLVQPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPF
GCRTGFHMIMWGRHTSAKIAAVIKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI

Sequences:

>Translated_160_residues
MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLVQPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPF
GCRTGFHMIMWGRHTSAKIAAVIKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
>Mature_159_residues
SKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLVQPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFG
CRTGFHMIMWGRHTSAKIAAVIKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=155, Percent_Identity=34.8387096774194, Blast_Score=116, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 17924; Mature: 17792

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLVQPNEDSIPTAGLHTIE
CCCCHHHHHHCCCHHHHHCCHHHEECCCCCCCCCEECCCCEEEECCCCCCCCCHHHHHHH
HLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAVIKDSLKEIAETTTWEDVP
HHHHHHHHHHHCCEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCC
GTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
CCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCC
>Mature Secondary Structure 
SKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLVQPNEDSIPTAGLHTIE
CCCHHHHHHCCCHHHHHCCHHHEECCCCCCCCCEECCCCEEEECCCCCCCCCHHHHHHH
HLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAVIKDSLKEIAETTTWEDVP
HHHHHHHHHHHCCEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCC
GTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
CCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA