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The map label for this gene is ctsR [H]

Identifier: 225859967

GI number: 225859967

Start: 2141858

End: 2142316

Strand: Reverse

Name: ctsR [H]

Synonym: SP70585_2323

Alternate gene names: 225859967

Gene position: 2142316-2141858 (Counterclockwise)

Preceding gene: 225859968

Following gene: 225859966

Centisome position: 98.06

GC content: 43.14

Gene sequence:

>459_bases
ATGAGATTTAAAAATACATCGGATCATATTGAGGCCTACATCAAGGCGATTTTAGATCAATCTGGTATCGTGGAGTTGCA
ACGGAGTCAGTTGGCAGATACCTTTCAGGTTGTTCCTAGTCAGATTAACTACGTGATCAAGACACGCTTTACGGAAAGTA
GAGGCTACTTGGTTGAAAGTAAGCGTGGTGGCGGAGGCTACATTCGTATAGGACGGATTGAGTTTTCTAGTCATCATGAA
ATGCTCCGGGAGCTGCTTTACTCGATTGGTGAGCGAGTCAGTCAAGAAATTTATGAGGATATTCTCCAGCTTTTGGTTGA
GCAGGAATTGATGACCAAGCAGGAGATGAATTTGCTAGAATCAGTAGCTTTGGATCGCGTTTTAGGAGAAGAAGCTCCAG
TTGTTCGAGCAAACATGCTACGTCAGGTCATACAAGAGGTAGATAGAAAAGGGAAGTAA

Upstream 100 bases:

>100_bases
AAGATTATCCTTTACCAGCGCCCTTTTTCTTTTAAAAATGAGAAAATTTCGGTATAATAGTCAAACAAGGTCAAGGTTTA
AAGAGAGAGGTGGGTTTGTT

Downstream 100 bases:

>100_bases
GATGAACTATTCAAAAGCATTGAATGAATGTATCGAAAGTGCCTACATGGTTGCTGGACATTTTGGAGCTCGTTATCTAG
AGTCGTGGCACTTGTTGATT

Product: transcriptional regulator CtsR

Products: NA

Alternate protein names: Class three stress gene repressor [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINYVIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHE
MLRELLYSIGERVSQEIYEDILQLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK

Sequences:

>Translated_152_residues
MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINYVIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHE
MLRELLYSIGERVSQEIYEDILQLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK
>Mature_152_residues
MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINYVIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHE
MLRELLYSIGERVSQEIYEDILQLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK

Specific function: Controls the expression of the cellular protein quality control genes clpC, clpE and clpP. Acts as a repressor of these class III stress genes by binding to a directly repeated heptanucleotide operator sequence (A/GGTCAAA NAN A/GGTCAAA). After heat shock,

COG id: COG4463

COG function: function code K; Transcriptional repressor of class III stress genes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CtsR family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008463 [H]

Pfam domain/function: PF05848 CtsR [H]

EC number: NA

Molecular weight: Translated: 17557; Mature: 17557

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINYVIKTRFTESRGYLVES
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEC
KRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDILQLLVEQELMTKQEMNLLE
CCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVALDRVLGEEAPVVRANMLRQVIQEVDRKGK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINYVIKTRFTESRGYLVES
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEC
KRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDILQLLVEQELMTKQEMNLLE
CCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVALDRVLGEEAPVVRANMLRQVIQEVDRKGK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]