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The map label for this gene is fucA [H]

Identifier: 225859931

GI number: 225859931

Start: 2096611

End: 2097339

Strand: Reverse

Name: fucA [H]

Synonym: SP70585_2285

Alternate gene names: 225859931

Gene position: 2097339-2096611 (Counterclockwise)

Preceding gene: 225859932

Following gene: 225859930

Centisome position: 96.0

GC content: 40.33

Gene sequence:

>729_bases
ATGTCTCAAGATGAAAAATTAATTCGTGAACAGATTTGTGATGTTTGTCATAAGATGTGGCAACTTGGTTGGGTTGCTGC
TAACGATGGGAATGTATCTGTTCGATTAGATGAGGATACCATTCTTGCAACACCTACTGGTATCAGCAAAAGTTTTATTA
CACCAGAAAAGCTGGTGAAGTTAAATCTTAAAGGAGAGATTTTAGAAGCAGAAGGTGATTACTGTCCTTCTAGTGAAATT
AAAATGCACATTCGGTGCTACGAAGAACGTGAGGATGTTCGTTCAGTTGTTCACGCGCATCCACCGATTGCAACAGGATT
TGCTCTTGCACACATTCCTTTAGATACTTATTCACTAATTGAGAGCGCGATTGTGGTAGGGGCAATTCCTATAACGCCAT
TTGGAGTTCCGTCTACAATGGAAGTGCCAGAAGCAATTACACCTTATCTGCCCGATCATGATGTCATGCTATTAGAAAAT
CATGGAGCTCTGACTGTCGGAAGCGATGTAATTACAGCATACTACCGTATGGAAACTTTAGAATTAGTCGCAAAGACAAC
CTTCCACGGAAGAATGTTACTTTCTACAAAGGGCATTGAGGAGCAAGAAATTGCTCGTCCGACTTTAGAACGTCTATTCT
CAATGCGAGAAAATTATAAGGTTACAGGTCGTCACCCAGGCTACCGTAAATATAATGGCGATGGTAGTATGAAAGAAACA
GAAAAATAA

Upstream 100 bases:

>100_bases
CATCTCTCAATTTTGATCAGAAAAATCATATGGTTACTATTACCATTAACAGTAACGGAAATCTTGAATTCGAACTTCAT
TTTTAGAAAGGAGTGAGTTT

Downstream 100 bases:

>100_bases
GAGGAAAATAGTATGATTCAACATCCACGTATTGGTATTCGTCCGACTATTGATGGTCGTCGTCAAGGTGTACGCGAATC
ACTTGAAGTACAAACAATGA

Product: L-fuculose phosphate aldolase

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSQDEKLIREQICDVCHKMWQLGWVAANDGNVSVRLDEDTILATPTGISKSFITPEKLVKLNLKGEILEAEGDYCPSSEI
KMHIRCYEEREDVRSVVHAHPPIATGFALAHIPLDTYSLIESAIVVGAIPITPFGVPSTMEVPEAITPYLPDHDVMLLEN
HGALTVGSDVITAYYRMETLELVAKTTFHGRMLLSTKGIEEQEIARPTLERLFSMRENYKVTGRHPGYRKYNGDGSMKET
EK

Sequences:

>Translated_242_residues
MSQDEKLIREQICDVCHKMWQLGWVAANDGNVSVRLDEDTILATPTGISKSFITPEKLVKLNLKGEILEAEGDYCPSSEI
KMHIRCYEEREDVRSVVHAHPPIATGFALAHIPLDTYSLIESAIVVGAIPITPFGVPSTMEVPEAITPYLPDHDVMLLEN
HGALTVGSDVITAYYRMETLELVAKTTFHGRMLLSTKGIEEQEIARPTLERLFSMRENYKVTGRHPGYRKYNGDGSMKET
EK
>Mature_241_residues
SQDEKLIREQICDVCHKMWQLGWVAANDGNVSVRLDEDTILATPTGISKSFITPEKLVKLNLKGEILEAEGDYCPSSEIK
MHIRCYEEREDVRSVVHAHPPIATGFALAHIPLDTYSLIESAIVVGAIPITPFGVPSTMEVPEAITPYLPDHDVMLLENH
GALTVGSDVITAYYRMETLELVAKTTFHGRMLLSTKGIEEQEIARPTLERLFSMRENYKVTGRHPGYRKYNGDGSMKETE
K

Specific function: Catalyzes the reversible aldol cleavage of L-fuculose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde [H]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Homo sapiens, GI9257190, Length=219, Percent_Identity=27.3972602739726, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI89276787, Length=219, Percent_Identity=27.3972602739726, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI297307160, Length=219, Percent_Identity=27.3972602739726, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI297307158, Length=219, Percent_Identity=27.3972602739726, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI9257192, Length=219, Percent_Identity=27.3972602739726, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI29826325, Length=238, Percent_Identity=26.890756302521, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI29826323, Length=238, Percent_Identity=26.890756302521, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI29826321, Length=238, Percent_Identity=26.890756302521, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI29826319, Length=238, Percent_Identity=26.890756302521, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1789094, Length=189, Percent_Identity=28.042328042328, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789164, Length=183, Percent_Identity=30.0546448087432, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 27116; Mature: 26985

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQDEKLIREQICDVCHKMWQLGWVAANDGNVSVRLDEDTILATPTGISKSFITPEKLVK
CCHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEEECCCEEEECCCCCCCCCCCHHHEEE
LNLKGEILEAEGDYCPSSEIKMHIRCYEEREDVRSVVHAHPPIATGFALAHIPLDTYSLI
ECCCCEEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCHHCEEEEECCCHHHHHH
ESAIVVGAIPITPFGVPSTMEVPEAITPYLPDHDVMLLENHGALTVGSDVITAYYRMETL
HHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEECCCCEEECHHHHHHHHHHHHH
ELVAKTTFHGRMLLSTKGIEEQEIARPTLERLFSMRENYKVTGRHPGYRKYNGDGSMKET
HHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCEECCCCCCCEEECCCCCCCCC
EK
CC
>Mature Secondary Structure 
SQDEKLIREQICDVCHKMWQLGWVAANDGNVSVRLDEDTILATPTGISKSFITPEKLVK
CHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEEECCCEEEECCCCCCCCCCCHHHEEE
LNLKGEILEAEGDYCPSSEIKMHIRCYEEREDVRSVVHAHPPIATGFALAHIPLDTYSLI
ECCCCEEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCHHCEEEEECCCHHHHHH
ESAIVVGAIPITPFGVPSTMEVPEAITPYLPDHDVMLLENHGALTVGSDVITAYYRMETL
HHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEECCCCEEECHHHHHHHHHHHHH
ELVAKTTFHGRMLLSTKGIEEQEIARPTLERLFSMRENYKVTGRHPGYRKYNGDGSMKET
HHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCEECCCCCCCEEECCCCCCCCC
EK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA