| Definition | Streptococcus pneumoniae 70585, complete genome. |
|---|---|
| Accession | NC_012468 |
| Length | 2,184,682 |
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The map label for this gene is licR [H]
Identifier: 225859904
GI number: 225859904
Start: 2064827
End: 2066857
Strand: Reverse
Name: licR [H]
Synonym: SP70585_2257
Alternate gene names: 225859904
Gene position: 2066857-2064827 (Counterclockwise)
Preceding gene: 225859909
Following gene: 225859903
Centisome position: 94.61
GC content: 33.28
Gene sequence:
>2031_bases ATGTTTGATTATAGAGCACTAGTTATTTTGATGACTTTGATGGATCATTGTGAGGTATCATTATATGAGTTATCTGTTAA GGTGAGCTTACCTATAAAGGAAGTCAAAGAAGGAATAGATTATTTAGTGCCTTATTTAGCTAATAAAGGGATAGTGCTGG ATAAAAAGCAAGGTCGCTATAGTTTATCAAATCGTACGAAGCAGTCTTTGACAGATATTATTAAGTCGGATGAATTGGTT TTACCAAAGTCGACTCGCTTAGCTTTAATCTATCTTTACACTTTTTGCCGATTAGATTTTATATCGAATAATCATTACCA AGACTTTTTGAAAGTAAGTAAGAATACAACCTTATCTGATATTCAATCATTAAGAAAGATTATGTTAGATAATGATTTGG AGCTAGGGTACAGTAGAGCAAAAGGTTATACTTTACACGGTTCAGAGTGGAATAAGCACCGTTTAGCTTTTCAAATGGTT AGTGAGTTGCTGGAATCCTCCATAGGGATTTGGGGTTTGGATTATGTTTTATCCAGTTGGGGGTATTCATTAACTTATGA TTTGATTGATCAGGTAGTTAAAGATTATTATGAGAAGCTACAGCTAGTACCTATTGTTAATCAATTAAAAGTTTACCTTT TCGGTTTAGTATTCATTCTGTGTAGGTATCAAAGGGATGTTGAAAGAGTATGTCTTTCAGAGACATTAGTATCTCCTGTT ATTCAAGATATAACGACTATTTTATTGGATACAGTGGTTGATTTGGGAATTATAGATACGGTGTTTTCTGAGGATGATTA TCGCTATATCACCGTTTTATTATCAAGTTGCTTTGAAGGTGAAGTAGATGTTGCTCCGGTTTACTTTAATCAATTAACAG AGGCTATTATAAGTAGAATGGAAGATATTTCTTTGTTACATTTTAAACAAAGGGAAGGATTGAGAGAAAATCTTCGCCGC CACCTTATACCGGCTTACTATAGATTAAAGTTCGGCCTACCTAGTTCAAATGAATATGTATTGCATGTTAAAGAACATTA TCCTGATTTATTTGAATTAGTCAAAGATTCTTTGATGCCCTTGATGGACGCTATTGACAATCCCATACCTGATAGTGAAA CAGCATATTTTGTTATCCATTTCGGAGGTTATTTAAAGAAAGCAGATACTTTGCCTCAAAAATGCTATAAAGCAGCAATC ATTTGTCCTAATGGTGTTAGTTCTTCATTGATGTTAAAAGAGAATCTATTAGCATTATTTCCTCAAATTGAGTTTATAGG AACCTCAAAGATTGATGATTTACAGGTGAAAGCTAGTAGTGACTATGATATGGTTTTTTCTACCATAAAGGTGGAGACAG AAAAGCCAAATTATCTAGTTTCGGTTATGATGACTGAAGAGCAAGCAATACAACTAGTAGAACTAGTGTTAAAAGATTTT CCGAATTTAGAGTATGGGGATTTTGAGATTGAACAAATCCTGAATATTGTCAAAAGATATGGAATTATTACACAAGAATT GGAATTAAGATTGGCGTTAAAGAATTATCTTTACCAAAAAAATGATAGAAAGGAAATTGTACCAGTGCTAGAACAACTCA TTACCAAAGAAACCTATCAGGTTAGTTCGCAAAAATTAGGATGGAAGGAGGCGATTCGTTTAGCAGCTAAACCGCTTTTG GATCAAGATAAGATAACTGAGAACTACCCTGAGGCAATGATTCAAAAAGTAGAAGAGTTTGGGCCTTTTATTAATTTAGG GAAGGGAGTAGCAATTCCTCACGCTCGGCCAGATGAAGGTGTGAATGAAATAGGAATGTCAATGTTAGTTTTGGAAGAAC CGATTTATTTATTGGATAATCCAGAACAAGAGGTAAGATTGTTGATTTGTATTGCAGCCATTGATAATGAGAGTCATTTA AAGGCTTTGTCACATTTAACAACAATTTTAAGAGATAAAAATCATGTTCAAACTTTAATATCATCAAAAAACTATGATGA CATTAAAATGATAATTAAACAGGAGGATTAG
Upstream 100 bases:
>100_bases AGCCCAATAATTTCTTTTAAAAGGTGAGATTATATTGTGCTCAAATACTCTTTTATTCTTATAACTTTTACACTATAATT GTAGTTAGAAAGGAAGAGAA
Downstream 100 bases:
>100_bases ATAATGTTAAAAATTGGTACAGCTTGTGGTTCAGGATTAGGTTCAAGTTTTATGGTACAGATGAATATTGAATCTGTATT GAGTGATTTGAATGTTTCGG
Product: transcriptional regulator, BglG family protein
Products: NA
Alternate protein names: Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]
Number of amino acids: Translated: 676; Mature: 676
Protein sequence:
>676_residues MFDYRALVILMTLMDHCEVSLYELSVKVSLPIKEVKEGIDYLVPYLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELV LPKSTRLALIYLYTFCRLDFISNNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVFILCRYQRDVERVCLSETLVSPV IQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSSCFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRR HLIPAYYRLKFGLPSSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLPQKCYKAAI ICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIKVETEKPNYLVSVMMTEEQAIQLVELVLKDF PNLEYGDFEIEQILNIVKRYGIITQELELRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLL DQDKITENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQEVRLLICIAAIDNESHL KALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED
Sequences:
>Translated_676_residues MFDYRALVILMTLMDHCEVSLYELSVKVSLPIKEVKEGIDYLVPYLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELV LPKSTRLALIYLYTFCRLDFISNNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVFILCRYQRDVERVCLSETLVSPV IQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSSCFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRR HLIPAYYRLKFGLPSSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLPQKCYKAAI ICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIKVETEKPNYLVSVMMTEEQAIQLVELVLKDF PNLEYGDFEIEQILNIVKRYGIITQELELRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLL DQDKITENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQEVRLLICIAAIDNESHL KALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED >Mature_676_residues MFDYRALVILMTLMDHCEVSLYELSVKVSLPIKEVKEGIDYLVPYLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELV LPKSTRLALIYLYTFCRLDFISNNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVFILCRYQRDVERVCLSETLVSPV IQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSSCFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRR HLIPAYYRLKFGLPSSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLPQKCYKAAI ICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIKVETEKPNYLVSVMMTEEQAIQLVELVLKDF PNLEYGDFEIEQILNIVKRYGIITQELELRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLL DQDKITENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQEVRLLICIAAIDNESHL KALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED
Specific function: Positive regulator of the licABCH operon [H]
COG id: COG3711
COG function: function code K; Transcriptional antiterminator
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIB type-2 domain [H]
Homologues:
Organism=Escherichia coli, GI1789302, Length=96, Percent_Identity=41.6666666666667, Blast_Score=79, Evalue=1e-15, Organism=Escherichia coli, GI2367359, Length=147, Percent_Identity=24.4897959183673, Blast_Score=79, Evalue=1e-15, Organism=Escherichia coli, GI1790755, Length=128, Percent_Identity=25.78125, Blast_Score=71, Evalue=2e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013196 - InterPro: IPR007737 - InterPro: IPR011608 - InterPro: IPR016152 - InterPro: IPR002178 - InterPro: IPR013011 - InterPro: IPR003501 - InterPro: IPR011991 [H]
Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF00359 PTS_EIIA_2; PF02302 PTS_IIB [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 77849; Mature: 77849
Theoretical pI: Translated: 4.85; Mature: 4.85
Prosite motif: PS00372 PTS_EIIA_TYPE_2_HIS ; PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFDYRALVILMTLMDHCEVSLYELSVKVSLPIKEVKEGIDYLVPYLANKGIVLDKKQGRY CCCHHHHHHHHHHHHHCCEEEEEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCCC SLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFISNNHYQDFLKVSKNTTLSD CHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHH IQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMVSELLESSIGIWGLDYVLSSW HHHHHHHHCCCCCCCCHHHCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHC GYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVFILCRYQRDVERVCLSETLVSPV CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH IQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSSCFEGEVDVAPVYFNQLTEAIISRM HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH EDISLLHFKQREGLRENLRRHLIPAYYRLKFGLPSSNEYVLHVKEHYPDLFELVKDSLMP HHHHHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCCEEEEEHHHCCHHHHHHHHHHHH LMDAIDNPIPDSETAYFVIHFGGYLKKADTLPQKCYKAAIICPNGVSSSLMLKENLLALF HHHHHCCCCCCCCCEEEEEEECCHHHHHHCCHHHHHHEEEECCCCCCCHHHHHHHHHHHC PQIEFIGTSKIDDLQVKASSDYDMVFSTIKVETEKPNYLVSVMMTEEQAIQLVELVLKDF CCCEEECCCCCCCEEEECCCCHHHEEEEEEEEECCCCEEEEEEECHHHHHHHHHHHHHHC PNLEYGDFEIEQILNIVKRYGIITQELELRLALKNYLYQKNDRKEIVPVLEQLITKETYQ CCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH VSSQKLGWKEAIRLAAKPLLDQDKITENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEG HHHHCCCHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCCEECCCCCCCCCCCCCCC VNEIGMSMLVLEEPIYLLDNPEQEVRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLI HHHHCCHHHHHHCCEEEECCCHHHEEEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHH SSKNYDDIKMIIKQED CCCCCCCEEEEEECCC >Mature Secondary Structure MFDYRALVILMTLMDHCEVSLYELSVKVSLPIKEVKEGIDYLVPYLANKGIVLDKKQGRY CCCHHHHHHHHHHHHHCCEEEEEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCCC SLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFISNNHYQDFLKVSKNTTLSD CHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHH IQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMVSELLESSIGIWGLDYVLSSW HHHHHHHHCCCCCCCCHHHCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHC GYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVFILCRYQRDVERVCLSETLVSPV CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH IQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSSCFEGEVDVAPVYFNQLTEAIISRM HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH EDISLLHFKQREGLRENLRRHLIPAYYRLKFGLPSSNEYVLHVKEHYPDLFELVKDSLMP HHHHHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCCEEEEEHHHCCHHHHHHHHHHHH LMDAIDNPIPDSETAYFVIHFGGYLKKADTLPQKCYKAAIICPNGVSSSLMLKENLLALF HHHHHCCCCCCCCCEEEEEEECCHHHHHHCCHHHHHHEEEECCCCCCCHHHHHHHHHHHC PQIEFIGTSKIDDLQVKASSDYDMVFSTIKVETEKPNYLVSVMMTEEQAIQLVELVLKDF CCCEEECCCCCCCEEEECCCCHHHEEEEEEEEECCCCEEEEEEECHHHHHHHHHHHHHHC PNLEYGDFEIEQILNIVKRYGIITQELELRLALKNYLYQKNDRKEIVPVLEQLITKETYQ CCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH VSSQKLGWKEAIRLAAKPLLDQDKITENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEG HHHHCCCHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCCEECCCCCCCCCCCCCCC VNEIGMSMLVLEEPIYLLDNPEQEVRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLI HHHHCCHHHHHHCCEEEECCCHHHEEEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHH SSKNYDDIKMIIKQED CCCCCCCEEEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8990303; 8969509; 9384377; 10438772 [H]