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The map label for this gene is endA [H]

Identifier: 225859892

GI number: 225859892

Start: 2055598

End: 2056155

Strand: Reverse

Name: endA [H]

Synonym: SP70585_2245

Alternate gene names: 225859892

Gene position: 2056155-2055598 (Counterclockwise)

Preceding gene: 225859893

Following gene: 225859891

Centisome position: 94.12

GC content: 43.19

Gene sequence:

>558_bases
ATGGCGAAGAAAAATTTGAAAAAACAGGCAATGAGCTTACTGGTGACTATAATTGCAGTAGCGGGTGGTTATCTTTTAAG
TGATAGCCAGAGTAGCACTCCTGCCAATTATTCCTATTATGTCAATCAGTCTAAGGCGAGTGAAGGGACTCCTAGTCAGG
AACTAGCTAGTTCGGTATTGACAGAAGAAGTCAAAAAGCAACTGGGGAATTCTATTGAATGGAATGGTGCTGGAGCCTTT
ATTATTAACGATAATCAGACGGATTTAAATGCCTCTGTTGCAAGTGTTCCTTACGGAGACAACAAGACAAAAACGGTGCA
GGGAGAAACTATTCCGACAGTAGCCAATGCGCTTTTAGCAAAATCTACACGTCAGTATAAGGATCGTGAAGAAACTAGAA
ATGGTCGGACTTCTTGGACACCTGCTGGTTGGCATCAGGTCCATGACTTAACTGGAGAATATGACCATGCAGTGGACCGA
GGTCACCTTCTGGGCTATGCCTTGATTGGTGGACTTTCAGGTTTTGATGCTTCGACCAGCAATCCTATAGTAGATTGA

Upstream 100 bases:

>100_bases
GTGACAATGTATTTGCGGTATTGTCACCTGCTAAGTGGCAGGAATTAATCGGTAAATTTACAGGAAAGTAGGCTGGTCCT
GCTTTTTTGATGGAGAGAAA

Downstream 100 bases:

>100_bases
AACTAGAATAGTACACATCTACTTCTAAAACATTGTTAGAAATCGATTTGACTGTCCTGATTGATTTGTCCTATTCTTAT
TTCACTTTACTATAAAAACA

Product: hypothetical protein

Products: NA

Alternate protein names: Competence-specific nuclease [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MAKKNLKKQAMSLLVTIIAVAGGYLLSDSQSSTPANYSYYVNQSKASEGTPSQELASSVLTEEVKKQLGNSIEWNGAGAF
IINDNQTDLNASVASVPYGDNKTKTVQGETIPTVANALLAKSTRQYKDREETRNGRTSWTPAGWHQVHDLTGEYDHAVDR
GHLLGYALIGGLSGFDASTSNPIVD

Sequences:

>Translated_185_residues
MAKKNLKKQAMSLLVTIIAVAGGYLLSDSQSSTPANYSYYVNQSKASEGTPSQELASSVLTEEVKKQLGNSIEWNGAGAF
IINDNQTDLNASVASVPYGDNKTKTVQGETIPTVANALLAKSTRQYKDREETRNGRTSWTPAGWHQVHDLTGEYDHAVDR
GHLLGYALIGGLSGFDASTSNPIVD
>Mature_184_residues
AKKNLKKQAMSLLVTIIAVAGGYLLSDSQSSTPANYSYYVNQSKASEGTPSQELASSVLTEEVKKQLGNSIEWNGAGAFI
INDNQTDLNASVASVPYGDNKTKTVQGETIPTVANALLAKSTRQYKDREETRNGRTSWTPAGWHQVHDLTGEYDHAVDRG
HLLGYALIGGLSGFDASTSNPIVD

Specific function: By degrading DNA that enters the cell, plays a role in the competence of cells to be transformed [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA/RNA non-specific endonuclease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018524
- InterPro:   IPR001604 [H]

Pfam domain/function: PF01223 Endonuclease_NS [H]

EC number: NA

Molecular weight: Translated: 19865; Mature: 19734

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS01070 NUCLEASE_NON_SPEC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKNLKKQAMSLLVTIIAVAGGYLLSDSQSSTPANYSYYVNQSKASEGTPSQELASSVL
CCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHH
TEEVKKQLGNSIEWNGAGAFIINDNQTDLNASVASVPYGDNKTKTVQGETIPTVANALLA
HHHHHHHHCCCCEECCCEEEEECCCCCCCCCEEEECCCCCCCCEEECCCCHHHHHHHHHH
KSTRQYKDREETRNGRTSWTPAGWHQVHDLTGEYDHAVDRGHLLGYALIGGLSGFDASTS
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCHHHHHCCHHHHHHHHHCCCCCCCCCCC
NPIVD
CCCCC
>Mature Secondary Structure 
AKKNLKKQAMSLLVTIIAVAGGYLLSDSQSSTPANYSYYVNQSKASEGTPSQELASSVL
CCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHH
TEEVKKQLGNSIEWNGAGAFIINDNQTDLNASVASVPYGDNKTKTVQGETIPTVANALLA
HHHHHHHHCCCCEECCCEEEEECCCCCCCCCEEEECCCCCCCCEEECCCCHHHHHHHHHH
KSTRQYKDREETRNGRTSWTPAGWHQVHDLTGEYDHAVDRGHLLGYALIGGLSGFDASTS
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCHHHHHCCHHHHHHHHHCCCCCCCCCCC
NPIVD
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2359120; 11463916 [H]