Click here to switch to the map view.

The map label for this gene is desK [H]

Identifier: 225859758

GI number: 225859758

Start: 1909144

End: 1910241

Strand: Reverse

Name: desK [H]

Synonym: SP70585_2074

Alternate gene names: 225859758

Gene position: 1910241-1909144 (Counterclockwise)

Preceding gene: 225859759

Following gene: 225859757

Centisome position: 87.44

GC content: 39.07

Gene sequence:

>1098_bases
ATGCTTGAAAGACTGAAAAGCATACACTATATGTTTTGGACCAGTTTGATTTTTATGCTTTTTCCCATCCTACCTGTAGT
GATTGGGGAGCTTCCTGCTTGGCATTTATTGGTTGATATTCTATTTGTAGTGACGTATTTGGGTGTTTTAATAACTAAGA
ACCAGCGCCTATCTTGGCTTTTCTGGGGGCTCATGCTGGTCTATGTAGCTGGGAATACCGCCTTTGTTGCTGGGAATTAT
ATCTGGTTTTTCTTTTTCCTTTCCAATCTCTTAATTTATCATTTTGGCGTACGTAGTTTAAAGTCTTTACATGTATGGAC
ATTTCTCCTTGCTCAAGTCCTTGTTGTGGGGCGACTTTTGATTTTTCAGAGAATCGAAGTTGAGTTTCTAGTCTATATGC
TTGTAATTCTTACTTTTGTCGATTTGATGACTTTGGGCTCGGTTCGAATTCGCCTTGTCGAGGATTTGAAAGAAGCTCAG
GTCAAGCAAAATACCCAGATAAATCTATTGCTAGCAGAAAATGAGCGCAATCGTATCGGTCAGGATTTGCATGATAGTCT
GGGACATACCTTTGCTATGCTTAGTGTCAAGACAGATCTAGCCTTGCAGCTATTTCAAATGCAGGCTTATCCACAAGTGG
AAAAGGAATTAAGAGAAATACAGCAAATTAGCAAAGAATCAATGTGTGAAGTTCGAACCATTGTGGAAAATCTTAAGTCT
AGAACTTTGACATCCGAACTAGAGACTGTGAAAAAGATGTTAGAAATTGCTGGAATTGAGGTGGAAACAGATAACCAACT
AGATACTGCTAGCCTTACTCAAGAATTGGATTCAATGGCTTCTATGATTTTGCTTGAGTTGGTGACCAATGTCATCAAAC
ATGCCAAAGCGTCTAAAGCTTACTTAAAATTAGAACGGACAGAGAAGGAACTCATTTTAACAGTAAGTGATGATGGCTGC
GGCTTTGCTTTTCTAAAAGGAGATGAGCTCCATACAGTCCGAGATCGTGTTTTTCCATTTTCAGGAGAAGTAAGTGTAAT
CAGTCAGAAACATCCAACGGAAGTGCAAGTTCGACTACCTTATAAGGAGAGAAACTAA

Upstream 100 bases:

>100_bases
AGGGGGACATCAATCTATCAGCCACAGTTTATTTACTTGTTTTTTCAGCAGTTTTATTTGGTTTGACTATTTACCTTCAA
GGTCATAAGGAGAATGCTTA

Downstream 100 bases:

>100_bases
GATGAAAGTATTAGTCGCAGAAGATCAAAGTATGTTGCGAGATGCCATGTGTCAATTGCTCACGCTTCAACCAGATGTGG
AGTCTGTCCTTCAAGCCAAG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVVTYLGVLITKNQRLSWLFWGLMLVYVAGNTAFVAGNY
IWFFFFLSNLLIYHFGVRSLKSLHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELREIQQISKESMCEVRTIVENLKS
RTLTSELETVKKMLEIAGIEVETDNQLDTASLTQELDSMASMILLELVTNVIKHAKASKAYLKLERTEKELILTVSDDGC
GFAFLKGDELHTVRDRVFPFSGEVSVISQKHPTEVQVRLPYKERN

Sequences:

>Translated_365_residues
MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVVTYLGVLITKNQRLSWLFWGLMLVYVAGNTAFVAGNY
IWFFFFLSNLLIYHFGVRSLKSLHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELREIQQISKESMCEVRTIVENLKS
RTLTSELETVKKMLEIAGIEVETDNQLDTASLTQELDSMASMILLELVTNVIKHAKASKAYLKLERTEKELILTVSDDGC
GFAFLKGDELHTVRDRVFPFSGEVSVISQKHPTEVQVRLPYKERN
>Mature_365_residues
MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVVTYLGVLITKNQRLSWLFWGLMLVYVAGNTAFVAGNY
IWFFFFLSNLLIYHFGVRSLKSLHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELREIQQISKESMCEVRTIVENLKS
RTLTSELETVKKMLEIAGIEVETDNQLDTASLTQELDSMASMILLELVTNVIKHAKASKAYLKLERTEKELILTVSDDGC
GFAFLKGDELHTVRDRVFPFSGEVSVISQKHPTEVQVRLPYKERN

Specific function: Member of the two-component regulatory system desR/desK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase. Acts as a sensor of the membrane fluidity. Probably activates desR by phosphorylation [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011712 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42104; Mature: 42104

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVVTYLGVLITKNQRLSWL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHH
FWGLMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKSLHVWTFLLAQVLVVGRLL
HHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQVKQNTQINLLLAENERNRIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHCC
QDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELREIQQISKESMCEVRTIVENLKS
HHHHHHHCHHEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTLTSELETVKKMLEIAGIEVETDNQLDTASLTQELDSMASMILLELVTNVIKHAKASKA
HHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLKLERTEKELILTVSDDGCGFAFLKGDELHTVRDRVFPFSGEVSVISQKHPTEVQVRLP
HHHHCCCCEEEEEEECCCCCCEEEEECCCHHHHHHHCCCCCCCEEEECCCCCCEEEEECC
YKERN
CCCCC
>Mature Secondary Structure
MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVVTYLGVLITKNQRLSWL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHH
FWGLMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKSLHVWTFLLAQVLVVGRLL
HHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQVKQNTQINLLLAENERNRIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHCC
QDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELREIQQISKESMCEVRTIVENLKS
HHHHHHHCHHEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTLTSELETVKKMLEIAGIEVETDNQLDTASLTQELDSMASMILLELVTNVIKHAKASKA
HHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLKLERTEKELILTVSDDGCGFAFLKGDELHTVRDRVFPFSGEVSVISQKHPTEVQVRLP
HHHHCCCCEEEEEEECCCCCCEEEEECCCHHHHHHHCCCCCCCEEEECCCCCCEEEEECC
YKERN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]