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The map label for this gene is ykrA [H]

Identifier: 225859753

GI number: 225859753

Start: 1904261

End: 1905649

Strand: Reverse

Name: ykrA [H]

Synonym: SP70585_2069

Alternate gene names: 225859753

Gene position: 1905649-1904261 (Counterclockwise)

Preceding gene: 225859755

Following gene: 225859751

Centisome position: 87.23

GC content: 43.63

Gene sequence:

>1389_bases
ATGGAAGTCAAAGCTGTTTTTTTTGATATCGATGGAACCTTGGTCAACAATCGCAAGAGTGTTTTGAAATCCACTAAGGA
TGCGATTAAGATTGTCAAAGAACAAGGGGTACTAGTTGGCGTAGCGACAGGGCGAGGACCTTTTTTTGTTAAGGAATTGA
TGGACGATTTGGATCTGGATTTTGCGGTAACCTATAATGGCCAGTATATCTTTAGTAAAGACAGAGTCTTGTTCACGAGC
CCTATTTCCAAGTTACATTTGCGCCATCTAATTAGCTATGCTAAAAAAGAGGGCACGGAGATTGCCCTAGGGACCAAGGA
TGCCATGTTGGGTTCTAAAATCATGTCCTTTGGTCTGGGTTCTTTTTCCCAACGAATTAGTCGCTTCGTTCCCTCTGTTT
TAACTCGGACGGTGAGTCAGTCTTTTAATCGCATGGTCAGCAAGGTTGTTCCCCAAAAGGAAGAGGACCTGCTTCACCTG
ATGAATCAGCCTATCTACCAAGTTTTGATGCTGATGACACCAGAAGAATCTGAGAAGGCGGCAGCTGATTTTGAAGACTT
GAAATTGACACGTAGCAATCCTTTTGCATCGGATGTCATCAATCAGGGAAATTCTAAATTAGAAGGCATTCGCCGAGTTG
GGAAAGAATATGGCTTTGACCTCAATCAAGTCATGGCTTTTGGTGACTCAGATAATGACCTTGAAATGCTGGCTGGCGTC
GGTATGTCGGTCGCTATGGGAAATGGTAGTAGCAGTGTCAAGGAAGCTGCCAAGCACATTACCACTAGCAATCAACAAGA
TGGGATCCACAAGGCCTTGGAACATTTTGGTGTTTTGTCTTCAGAAAAAGTCTTTGTCAGCCGTGACTATCATTTCAATA
AGGTCAAGACCTTCCACCACATGATGGATGAACGAACCCAAGAAGAACCTCGAGCTTGGGATTTAGAGGGTGCAACCCAT
AGGGCTGGTTTTAAAATAGAAGAATTGGTGGAGTTTGTTCGAGCAGCCAGTCCTTCTGAAGAAGATTTTGGTCAAGCTGT
ATCGCAACTTCATCAGGCCCTTGATAAGGCAGCAGATAAAGTAGCCAAGAAGACACCTGCTCAGCAAGATTTGATAGGGC
AAGTGGATGCCTTGATTGACACGCTTTACTTCACCTACGGCAGTTTTGTCTTGATGGGGGTGGACCCAGAACGTATTTTT
GATATTGTCCATCAGGCCAATATGGGGAAAATTTTTCCAGATGGCAAGGCTCATTTTGATCCAGTGACCCATAAAATCTT
AAAACCAGATAATTGGGAAGAAAAATATGCTCCAGAACCTGCTATTAAAAAGGAACTGCAGCGCCAGCTCAAGGCTTACG
AACGCCATAAAGAGAGAAATAAATCGTAA

Upstream 100 bases:

>100_bases
CCACCCGTATGTAAAACAAGGATTTTCTTAGGCATGATTTACTAACTCTTTCTGAAATGTGGTATAATCATTGTATCACA
AAAGGGGAGATTGGGATAGG

Downstream 100 bases:

>100_bases
ACAAAAAGGAGCTAGGGGCTCCTTTTCTTTGTGATTATAAGGTTTTTTCTTGTTCTCTCACAACCAGCAAATCGACCTTA
GCATGGCGGAGTATGTATTC

Product: Cof family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATGRGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTS
PISKLHLRHLISYAKKEGTEIALGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYGFDLNQVMAFGDSDNDLEMLAGV
GMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHFGVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATH
RAGFKIEELVEFVRAASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLMGVDPERIF
DIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQLKAYERHKERNKS

Sequences:

>Translated_462_residues
MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATGRGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTS
PISKLHLRHLISYAKKEGTEIALGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYGFDLNQVMAFGDSDNDLEMLAGV
GMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHFGVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATH
RAGFKIEELVEFVRAASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLMGVDPERIF
DIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQLKAYERHKERNKS
>Mature_462_residues
MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATGRGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTS
PISKLHLRHLISYAKKEGTEIALGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYGFDLNQVMAFGDSDNDLEMLAGV
GMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHFGVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATH
RAGFKIEELVEFVRAASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLMGVDPERIF
DIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQLKAYERHKERNKS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI2367265, Length=293, Percent_Identity=26.962457337884, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787043, Length=277, Percent_Identity=25.9927797833935, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081790, Length=289, Percent_Identity=25.6055363321799, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 51899; Mature: 51899

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS01228 COF_1 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATGRGPFFVKELMDDLDLD
CCCEEEEEECCCCEECCHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCC
FAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIALGTKDAMLGSKIMSFGLG
EEEEECCEEEEECCCEEEECCHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHCCC
SFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHLMNQPIYQVLMLMTPEESEKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
AADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYGFDLNQVMAFGDSDNDLEMLAGV
HCCHHHHEECCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHCC
GMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHFGVLSSEKVFVSRDYHFNKVKTFHH
CCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHH
MMDERTQEEPRAWDLEGATHRAGFKIEELVEFVRAASPSEEDFGQAVSQLHQALDKAADK
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VAKKTPAQQDLIGQVDALIDTLYFTYGSFVLMGVDPERIFDIVHQANMGKIFPDGKAHFD
HHHHCCCHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCC
PVTHKILKPDNWEEKYAPEPAIKKELQRQLKAYERHKERNKS
HHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATGRGPFFVKELMDDLDLD
CCCEEEEEECCCCEECCHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCC
FAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIALGTKDAMLGSKIMSFGLG
EEEEECCEEEEECCCEEEECCHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHCCC
SFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHLMNQPIYQVLMLMTPEESEKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
AADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYGFDLNQVMAFGDSDNDLEMLAGV
HCCHHHHEECCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHCC
GMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHFGVLSSEKVFVSRDYHFNKVKTFHH
CCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHH
MMDERTQEEPRAWDLEGATHRAGFKIEELVEFVRAASPSEEDFGQAVSQLHQALDKAADK
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VAKKTPAQQDLIGQVDALIDTLYFTYGSFVLMGVDPERIFDIVHQANMGKIFPDGKAHFD
HHHHCCCHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCC
PVTHKILKPDNWEEKYAPEPAIKKELQRQLKAYERHKERNKS
HHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]