Click here to switch to the map view.

The map label for this gene is yabD [H]

Identifier: 225859747

GI number: 225859747

Start: 1899663

End: 1900436

Strand: Reverse

Name: yabD [H]

Synonym: SP70585_2063

Alternate gene names: 225859747

Gene position: 1900436-1899663 (Counterclockwise)

Preceding gene: 225859748

Following gene: 225859746

Centisome position: 86.99

GC content: 45.48

Gene sequence:

>774_bases
ATGATTTTTGATACACATACACACTTGAATGTAGAAGAATTTGCAGGTCGTGAGGCAGAAGAAATTGCCTTGGCTGATGA
GATGGGTGTGACACAGATGAATATTGTTGGTTTTGATAAACCGACGATTGAGCATGCCTTGGAGTTGGTAGATGAGTATG
AGCAGCTCTATGCGACTATTGGTTGGCATCCTACAGAAGCTGGTACTTATACAGAGGAAGTTGAGGCTTACTTGTTGGAT
AAGTTAAAACATTCCAAGGTTGTGGCTTTAGGTGAAATTGGCTTAGACTACCATTGGATGACAGCGCCCAAAGAGGTGCA
GGAGCAGGTTTTTCGCCGTCAGATTCAGCTATCTAAGGACTTGGATTTGCCTTTTGTTGTCCATACCCGTGATGCGCTGG
AAGATACCTATGAGATTATCAAGAGTGAGGGCGTTGGTCCTCGTGGTGGTATCATGCATTCATTTTCAGGGACGCTTGAG
TGGGCAGAGAAGTTTGTGGATCTTGGTATGACCATTTCCTTCTCAGGAGTGGTGACTTTCAAGAAGGCAACTGACCTCCA
AGAAGCAGCTAAAGAGTTACCTTTGGACAAGATGTTGGTGGAAACAGATGCGCCTTACTTAGCACCTGTACCCAAGCGTG
GTCGTGAAAATAAAACAGCCTATACTCGCTATGTGGTCGACTTTATCGCTGACTTGCGTGGTATGACGACAGAAGAGCTA
GCGGCGGCAACGACTGCAAATGCAGAACGCATTTTTGGATTGGACAGCAAGTAA

Upstream 100 bases:

>100_bases
CAGAATAGCTCTCTATTGAAGAGAGGAGGGGAAACCGAAAAATTAGGTGCCCCTCCTCTTTTTTGGTATAATAGAAGGAT
AGAAAACGAGGTTAGAAGAG

Downstream 100 bases:

>100_bases
TGAAAGAGAAAATTTCCCAAGTAATTGTGGTTGAAGGGCGTGATGATACGGTCAATCTCAAACGTTATTTCGATGTGGAG
ACCTATGAGACTCGAGGTTC

Product: deoxyribonuclease TatD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIEHALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLD
KLKHSKVVALGEIGLDYHWMTAPKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENKTAYTRYVVDFIADLRGMTTEEL
AAATTANAERIFGLDSK

Sequences:

>Translated_257_residues
MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIEHALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLD
KLKHSKVVALGEIGLDYHWMTAPKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENKTAYTRYVVDFIADLRGMTTEEL
AAATTANAERIFGLDSK
>Mature_257_residues
MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIEHALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLD
KLKHSKVVALGEIGLDYHWMTAPKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENKTAYTRYVVDFIADLRGMTTEEL
AAATTANAERIFGLDSK

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=272, Percent_Identity=34.1911764705882, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI14042943, Length=194, Percent_Identity=33.5051546391753, Blast_Score=110, Evalue=9e-25,
Organism=Homo sapiens, GI225903439, Length=181, Percent_Identity=33.1491712707182, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI110349730, Length=265, Percent_Identity=27.9245283018868, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI110349734, Length=265, Percent_Identity=27.9245283018868, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI226061853, Length=270, Percent_Identity=27.7777777777778, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI226061614, Length=256, Percent_Identity=27.34375, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI226061595, Length=227, Percent_Identity=28.1938325991189, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1787342, Length=264, Percent_Identity=39.0151515151515, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI48994985, Length=258, Percent_Identity=31.3953488372093, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI87082439, Length=255, Percent_Identity=30.9803921568627, Blast_Score=134, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17559024, Length=258, Percent_Identity=27.1317829457364, Blast_Score=116, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI71980746, Length=264, Percent_Identity=27.6515151515151, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17543026, Length=218, Percent_Identity=28.4403669724771, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17565396, Length=179, Percent_Identity=30.1675977653631, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI221330018, Length=181, Percent_Identity=35.3591160220994, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24586117, Length=181, Percent_Identity=35.3591160220994, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24648690, Length=285, Percent_Identity=29.4736842105263, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28891; Mature: 28891

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIEHALELVDEYEQLYATI
CEECCCCCCCHHHHCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
GWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTAPKEVQEQVFRRQIQLSKD
CCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHCC
LDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLEWAEKFVDLGMTISFSGVVTF
CCCCEEEECHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHCCCEEEECCEEEE
KKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENKTAYTRYVVDFIADLRGMTTEEL
HHHCCHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHH
AAATTANAERIFGLDSK
HHHHCCCHHHEECCCCC
>Mature Secondary Structure
MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIEHALELVDEYEQLYATI
CEECCCCCCCHHHHCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
GWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTAPKEVQEQVFRRQIQLSKD
CCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHCC
LDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLEWAEKFVDLGMTISFSGVVTF
CCCCEEEECHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHCCCEEEECCEEEE
KKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENKTAYTRYVVDFIADLRGMTTEEL
HHHCCHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHH
AAATTANAERIFGLDSK
HHHHCCCHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]