Click here to switch to the map view.

The map label for this gene is treC

Identifier: 225859645

GI number: 225859645

Start: 1797212

End: 1798837

Strand: Reverse

Name: treC

Synonym: SP70585_1938

Alternate gene names: 225859645

Gene position: 1798837-1797212 (Counterclockwise)

Preceding gene: 225859646

Following gene: 225859644

Centisome position: 82.34

GC content: 41.57

Gene sequence:

>1626_bases
ATGACACTTGATAAAGGAAAAGTAGTCTATCAAATCTATCCAAAATCTTACAAAGACACCACTGAAAACGGTATTGGGGA
TTTCCGTGGGATTATCGAAAAAATTCCCTATTTAGCCAAACTAGGTGTGGATATGGTCTGGCTCAATCCATTCTATCCAA
GCCCTCAACGGGATAATGGTTACGATATTTCAGATTATATGGCAGTGGATCCTCTTTTTGGTGATATGGCTGATTTTGAG
GAAATGGTGTGTGTCGGTAAAGAGCACAAGATTGACTTTATGCTGGACATGGTACTTAATCATTGTTCGACAGAGCATGA
ATGGTTTCAGAAAGCCCTAGCTGGTGATAAGTATTATCAAGACTTTTTCTTCATCCAAGACCAATCAACAGATTGGCAGT
CTAAGTTTGGTGGTTCTGCATGGGCGCCTTTCGGGGATACTGGGAAATACTATCTTCACCTATTTGATGAGACCCAGGCT
GACCTTAACTGGCGCAATCCCAATGTCCGTAAGGAGCTTTTCAAGGTTGTTAATTTCTGGCGCGACAAGGGTGTCAAAGG
TTTTCGATTTGATGTGATCAATTTGATCGGTAAGGACGAGGTTTCAGTGGACTGTCCTGAAAATGAAGGGAAGCCAGCTT
ATACAGACAAACCCATCGTTCATAACTATTTGCGTATGATGAACCAAGCCACTTTTGGATCTGACGATAGCTTTATGACA
GTTGGGGAAATGTCTTCTACCACCATGGAAAACTGTGTCCTTTATTCGTCGCCTGATCGTCAGGAATTATCCATGACCTT
TAATTTTCATCACCTCAAGGTGGACTATAAGGATGGACAAAAGTGGACCTTGGCTCCCTTTGATTTTGAAGAGTTGAAGA
GTCTTTACCATAGTTGGGGTAAGGAAATGAGTGATAAAGACGGTTGGAGTGCCCTCTTTTGGAACAATCACGATCAACCA
CGTGCCTTGAACCGTTTTGTCGATATTCAAAACTTCCGCAAGGAAGGAGCCACCATGCTAGCAGCCAGCATTCACCTGTC
ACGTGGGACACCTTATATCTACATGGGTGAGGAAATCGGGATGATTGACCCAGACTATGATTCTATGGCTGATTATGTGG
ATGTCGAATCGCTTAATGCCTATCAGATGCTCTTAGAAGAAGGAAAGAGTCAGCAAGAAGCCTTCCAGATTATTCAAGCT
AAGTCGCGTGATAATTCACGCATTCCCATGCAGTGGGATGCTTCGGAAAATGCAGGATTTTCAACAGGCACTCCTTGGTT
GAAAGCTGGTAAATCCTATAAATACATCAATGTAGAAAATGAAATCCAGGGTCCGATTTTTACCTTCTATCAAGACTTGA
TTCGACTGCGTAAGGAAATGCCAATCATTTCAGAAGGAAGTTACAAACCAGCCTTTGAAGATAGCAAACAAGTCTACGCT
TTTGAACGCCAGTTTGAGGATCAAAAGTTACTAGTGCTCAATAACTTTTATGCTAAAGAAGTGGAAATCGACTTGCCAGC
AGTCTACCAAAATGGACAGATTTTGATATCAAACTATGAAGATGCAGAAGTGTCTGAGAAAATTCTACTCAAACCCTATC
AAACACTGGCTATTTATGTAAATTAA

Upstream 100 bases:

>100_bases
GCTTCCTAGTTTGTTCTTTGATTTTCATTGAGTATAATTGAAATAGCACAAATAGGGACGGAAGACTGCTTCCTCCCTTT
TATCAGAAAAGGAGAAACAG

Downstream 100 bases:

>100_bases
TACTCTTCGAAAATCTCTTCAAACCACGTCAGTTTTATCTGCAACCTCAAAGCGGTGCTTTGAGCAACCTGTGGCTAGCT
TCCTAGTTTGCTCTTTGATT

Product: alpha,alpha-phosphotrehalase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVDMVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFE
EMVCVGKEHKIDFMLDMVLNHCSTEHEWFQKALAGDKYYQDFFFIQDQSTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKPIVHNYLRMMNQATFGSDDSFMT
VGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDYKDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQP
RALNRFVDIQNFRKEGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQEAFQIIQA
KSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFYQDLIRLRKEMPIISEGSYKPAFEDSKQVYA
FERQFEDQKLLVLNNFYAKEVEIDLPAVYQNGQILISNYEDAEVSEKILLKPYQTLAIYVN

Sequences:

>Translated_541_residues
MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVDMVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFE
EMVCVGKEHKIDFMLDMVLNHCSTEHEWFQKALAGDKYYQDFFFIQDQSTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKPIVHNYLRMMNQATFGSDDSFMT
VGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDYKDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQP
RALNRFVDIQNFRKEGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQEAFQIIQA
KSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFYQDLIRLRKEMPIISEGSYKPAFEDSKQVYA
FERQFEDQKLLVLNNFYAKEVEIDLPAVYQNGQILISNYEDAEVSEKILLKPYQTLAIYVN
>Mature_540_residues
TLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVDMVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEE
MVCVGKEHKIDFMLDMVLNHCSTEHEWFQKALAGDKYYQDFFFIQDQSTDWQSKFGGSAWAPFGDTGKYYLHLFDETQAD
LNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKPIVHNYLRMMNQATFGSDDSFMTV
GEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDYKDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPR
ALNRFVDIQNFRKEGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQEAFQIIQAK
SRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFYQDLIRLRKEMPIISEGSYKPAFEDSKQVYAF
ERQFEDQKLLVLNNFYAKEVEIDLPAVYQNGQILISNYEDAEVSEKILLKPYQTLAIYVN

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=524, Percent_Identity=27.8625954198473, Blast_Score=186, Evalue=7e-47,
Organism=Escherichia coli, GI1790687, Length=537, Percent_Identity=46.927374301676, Blast_Score=507, Evalue=1e-145,
Organism=Escherichia coli, GI1786604, Length=179, Percent_Identity=27.9329608938547, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI87081873, Length=160, Percent_Identity=30, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32565753, Length=196, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25147709, Length=197, Percent_Identity=28.4263959390863, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321726, Length=576, Percent_Identity=34.375, Blast_Score=304, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6322241, Length=576, Percent_Identity=34.375, Blast_Score=301, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6322021, Length=576, Percent_Identity=34.375, Blast_Score=301, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6324416, Length=576, Percent_Identity=34.375, Blast_Score=300, Evalue=3e-82,
Organism=Saccharomyces cerevisiae, GI6321731, Length=568, Percent_Identity=34.1549295774648, Blast_Score=295, Evalue=1e-80,
Organism=Saccharomyces cerevisiae, GI6319776, Length=568, Percent_Identity=33.9788732394366, Blast_Score=293, Evalue=5e-80,
Organism=Saccharomyces cerevisiae, GI6322245, Length=562, Percent_Identity=31.6725978647687, Blast_Score=275, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24586591, Length=567, Percent_Identity=32.8042328042328, Blast_Score=231, Evalue=9e-61,
Organism=Drosophila melanogaster, GI24586593, Length=530, Percent_Identity=31.8867924528302, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24583747, Length=537, Percent_Identity=33.147113594041, Blast_Score=225, Evalue=5e-59,
Organism=Drosophila melanogaster, GI24583749, Length=537, Percent_Identity=33.147113594041, Blast_Score=225, Evalue=6e-59,
Organism=Drosophila melanogaster, GI24583745, Length=579, Percent_Identity=30.0518134715026, Blast_Score=224, Evalue=8e-59,
Organism=Drosophila melanogaster, GI221330053, Length=585, Percent_Identity=30.4273504273504, Blast_Score=220, Evalue=2e-57,
Organism=Drosophila melanogaster, GI45549022, Length=573, Percent_Identity=31.413612565445, Blast_Score=219, Evalue=5e-57,
Organism=Drosophila melanogaster, GI24586589, Length=541, Percent_Identity=31.2384473197782, Blast_Score=217, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24586599, Length=537, Percent_Identity=30.7262569832402, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24586597, Length=532, Percent_Identity=30.2631578947368, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24586587, Length=583, Percent_Identity=26.2435677530017, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI281360393, Length=482, Percent_Identity=30.0829875518672, Blast_Score=168, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 62818; Mature: 62687

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVDMVWLNPFYPSPQRDNG
CCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCEEEECCCCCCCCCCCC
YDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHCSTEHEWFQKALAGDKYYQ
CCHHHHEEECCHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHC
DFFFIQDQSTDWQSKFGGSAWAPFGDTGKYYLHLFDETQADLNWRNPNVRKELFKVVNFW
EEEEEECCCCCHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
RDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKPIVHNYLRMMNQATFGSDDSFMT
HHCCCCCEEEHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
VGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDYKDGQKWTLAPFDFEELKSLYHSWG
ECCCCCCCHHCEEEECCCCCCEEEEEEEEEEEEEEECCCCEEEECCCCHHHHHHHHHHHC
KEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRKEGATMLAASIHLSRGTPYIYMGEEIG
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEECCCCC
MIDPDYDSMADYVDVESLNAYQMLLEEGKSQQEAFQIIQAKSRDNSRIPMQWDASENAGF
CCCCCHHHHHHHHCHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCCC
STGTPWLKAGKSYKYINVENEIQGPIFTFYQDLIRLRKEMPIISEGSYKPAFEDSKQVYA
CCCCHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHEEH
FERQFEDQKLLVLNNFYAKEVEIDLPAVYQNGQILISNYEDAEVSEKILLKPYQTLAIYV
HHHCCCCCEEEEEECCEEEEEEEECCEEECCCEEEEECCCCCHHHHHHHCCCCEEEEEEE
N
C
>Mature Secondary Structure 
TLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVDMVWLNPFYPSPQRDNG
CCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCEEEECCCCCCCCCCCC
YDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHCSTEHEWFQKALAGDKYYQ
CCHHHHEEECCHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHC
DFFFIQDQSTDWQSKFGGSAWAPFGDTGKYYLHLFDETQADLNWRNPNVRKELFKVVNFW
EEEEEECCCCCHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
RDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKPIVHNYLRMMNQATFGSDDSFMT
HHCCCCCEEEHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
VGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDYKDGQKWTLAPFDFEELKSLYHSWG
ECCCCCCCHHCEEEECCCCCCEEEEEEEEEEEEEEECCCCEEEECCCCHHHHHHHHHHHC
KEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRKEGATMLAASIHLSRGTPYIYMGEEIG
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEECCCCC
MIDPDYDSMADYVDVESLNAYQMLLEEGKSQQEAFQIIQAKSRDNSRIPMQWDASENAGF
CCCCCHHHHHHHHCHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCCC
STGTPWLKAGKSYKYINVENEIQGPIFTFYQDLIRLRKEMPIISEGSYKPAFEDSKQVYA
CCCCHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHEEH
FERQFEDQKLLVLNNFYAKEVEIDLPAVYQNGQILISNYEDAEVSEKILLKPYQTLAIYV
HHHCCCCCEEEEEECCEEEEEEEECCEEECCCEEEEECCCCCHHHHHHHCCCCEEEEEEE
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7651129; 8969503; 9384377; 7751281 [H]