Click here to switch to the map view.

The map label for this gene is opuCB [H]

Identifier: 225859623

GI number: 225859623

Start: 1779790

End: 1781310

Strand: Reverse

Name: opuCB [H]

Synonym: SP70585_1916

Alternate gene names: 225859623

Gene position: 1781310-1779790 (Counterclockwise)

Preceding gene: 225859624

Following gene: 225859622

Centisome position: 81.54

GC content: 43.46

Gene sequence:

>1521_bases
ATGACTAATTTAATTGCAACTTTTCAGGATCGTTTTAGTGATTGGTTGACAGCTCTATCTCAACATTTGCAGTTGTCACT
TTTGACCTTGTTACTAGCTATTTTGCTTGCGATTCCCTTGGCTGTTTTTCTTCGCTATCATGAGAAGCTGGCTGACTGGG
TCTTGCAGATTGCAGGTATTTTCCAGACCATCCCGTCTCTGGCCTTGTTGGGGCTCTTTATCCCTTTGATGGGAATTGGG
ACCTTGCCGGCTTTGACAGCTCTAGTGATTTATGCGATTTTCCCTATTTTGCAAAATACTATCACTGGGCTGAAGGGAAT
TGATCCGAACCTGCAAGAGGCTGGGATTGCCTTTGGGATGACCAGATGGGAACGTCTCAAGAAATTTGAAATTCCACTCG
CCATGCCTGTTATCATGTCTGGGATTCGGACGGCAGCTGTTTTGATTATCGGTACGGCAACCTTGGCGGCCTTGATTGGA
GCAGGGGGACTGGGTTCCTTTATCCTGTTGGGAATTGACCGTAATAATGCCAGTTTGATTTTGATTGGGGCCCTTTCTTC
TGCAGTGCTTGCTATTGCCTTTAACTTCCTACTAAAAGTAATGGAAAAAGCAAAATTACGGACGATTTTCTCAGGTTTTG
CCTTGGTGACGGTATTGCTGGGTCTATCTTATAGTCCAGCCCTCTTGGTTCAAAAAGAGAAGGAAAACTTGATTATTGCT
GGGAAAATAGGCCCAGAACCAGAAATTTTGGCTAATATGTATAAATTGCTGATTGAAGAAAATACCAGCATGACTGCGAC
TGTTAAACCGAATTTTGGGACGACAAGTTTCCTTTATGAAGCTCTGAAAAAAGGTGATATTGACATTTATCCTGAATTTA
CCGGTACGGTGACTGAAAGTTTGCTTCAACCATCACCCAAGGTGAGTCATGAGCCAGAGCAGGTTTATCAAGTGGCGCGT
GATGGCATTGCCAAGCAGGATCATCTAGCCTATCTCAAACCTATGTCTTATCAAAATACCTATGCTGTAGCTGTTCCGAA
AAAGATTGCTCAAGAATATGGCTTGAAGACCATTTCGGATTTGAAAAAAGTGGAAGGGCAGCTGAAGGCAGGCTTTACGC
TTGAGTTTAACGACCGTGAAGATGGAAATAAGGGCTTGCAATCAATGTATGGTCTCAATCTCAATGTGGCGACTATGCAG
CCAGCTCTTCGTTATCAGGCAATTCAGTCAGGGGATATTCAAATCACGGATGCCTATTCGACTGATGCGGAATTGGAGCG
TTATGATTTACAGGTCTTGGAAGATGACAAGCAACTCTTCCCACCTTATCAAGGGGCTCCACTCATGAAAGAAGCTCTTC
TCAAGAAACACCCAGAGTTGGAAAGAGTTCTTAATAAATTGGCTGGTAAGATTACAGAAAGTCAGATGAGCCAACTTAAC
TATCAAGTGGGTGTCGAAGGCAAGTCAGCAAAGCAAGTAGCCAAGGAGTTTCTCCAAGAACAAGGTTTGTTGAAGAAATG
A

Upstream 100 bases:

>100_bases
GTCTTGCAGGATGGAGAAATTCGCCAGGTAGCGAATCCCGAGACAATTTTAAAAGCGCCTGCAACAGACTTTGTAGCAGA
CTTGTTTGGAGGTAGTGTTC

Downstream 100 bases:

>100_bases
TGGGACAGAGACTTTAAACATACTGAACTCAACTTCCTTAAACGACTAGATAAAAGAATGCTCAGACAATTTCGTCTGGG
CTTTTTTGATGTGAGAATGA

Product: choline transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFLRYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIG
TLPALTALVIYAIFPILQNTITGLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVTVLLGLSYSPALLVQKEKENLIIA
GKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTSFLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVAR
DGIAKQDHLAYLKPMSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGLNLNVATMQ
PALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMKEALLKKHPELERVLNKLAGKITESQMSQLN
YQVGVEGKSAKQVAKEFLQEQGLLKK

Sequences:

>Translated_506_residues
MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFLRYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIG
TLPALTALVIYAIFPILQNTITGLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVTVLLGLSYSPALLVQKEKENLIIA
GKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTSFLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVAR
DGIAKQDHLAYLKPMSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGLNLNVATMQ
PALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMKEALLKKHPELERVLNKLAGKITESQMSQLN
YQVGVEGKSAKQVAKEFLQEQGLLKK
>Mature_505_residues
TNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFLRYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGT
LPALTALVIYAIFPILQNTITGLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIGA
GGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVTVLLGLSYSPALLVQKEKENLIIAG
KIGPEPEILANMYKLLIEENTSMTATVKPNFGTTSFLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARD
GIAKQDHLAYLKPMSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGLNLNVATMQP
ALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMKEALLKKHPELERVLNKLAGKITESQMSQLNY
QVGVEGKSAKQVAKEFLQEQGLLKK

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1732

COG function: function code M; Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=148, Percent_Identity=40.5405405405405, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788452, Length=278, Percent_Identity=26.6187050359712, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1788451, Length=203, Percent_Identity=34.4827586206897, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1789033, Length=172, Percent_Identity=30.8139534883721, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 55586; Mature: 55455

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFLRYHEKLADWVLQIAGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTITGLKGIDPNLQEAGIAFGM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
TRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIGAGGLGSFILLGIDRNNASLI
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEE
LIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVTVLLGLSYSPALLVQKEKENLIIA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEE
GKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTSFLYEALKKGDIDIYPEFTGTVTES
ECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCEECCCCCHHHHHH
LLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKPMSYQNTYAVAVPKKIAQEYGLKTISD
HHCCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCCCCEEEECCHHHHHHHCCHHHHH
LKKVEGQLKAGFTLEFNDREDGNKGLQSMYGLNLNVATMQPALRYQAIQSGDIQITDAYS
HHHHHHHHHCCEEEEECCCCCCHHHHHHHHCCCCCHHHHCHHHHHHHHCCCCEEEEECCC
TDAELERYDLQVLEDDKQLFPPYQGAPLMKEALLKKHPELERVLNKLAGKITESQMSQLN
CCCHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
YQVGVEGKSAKQVAKEFLQEQGLLKK
CEECCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFLRYHEKLADWVLQIAGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTITGLKGIDPNLQEAGIAFGM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
TRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIGAGGLGSFILLGIDRNNASLI
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEE
LIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVTVLLGLSYSPALLVQKEKENLIIA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEE
GKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTSFLYEALKKGDIDIYPEFTGTVTES
ECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCEECCCCCHHHHHH
LLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKPMSYQNTYAVAVPKKIAQEYGLKTISD
HHCCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCCCCEEEECCHHHHHHHCCHHHHH
LKKVEGQLKAGFTLEFNDREDGNKGLQSMYGLNLNVATMQPALRYQAIQSGDIQITDAYS
HHHHHHHHHCCEEEEECCCCCCHHHHHHHHCCCCCHHHHCHHHHHHHHCCCCEEEEECCC
TDAELERYDLQVLEDDKQLFPPYQGAPLMKEALLKKHPELERVLNKLAGKITESQMSQLN
CCCHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
YQVGVEGKSAKQVAKEFLQEQGLLKK
CEECCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]